Activation of c-myc and c-K-ras oncogenes in primary rat tumors induced by ionizing radiation.
Sawey, M J, Hood, A T, Burns, F J, Garte, S J
An activated K-ras oncogene was detected by transfection in NIH 3T3 cells and by Southern blot analysis in 6 of 12 rat skin tumors induced by ionizing radiation. The DNA from 10 of the 12 tumors also...
Transforming gene in human atherosclerotic plaque DNA.
Penn, A, Garte, S J, Warren, L, Nesta, D, Mindich, B
The monoclonal hypothesis equates atherosclerotic plaques with benign smooth muscle cell tumors and proposes that plaques can arise via mutational or viral events. Here, we provide direct evidence...
Relationship between ambient air pollution and DNA damage in Polish mothers and newborns.
Whyatt, R M, Santella, R M, Jedrychowski, W, Garte, S J, Bell, D A, Ottman, R, ...
Industrialized regions in Poland are characterized by high ambient pollution, including polycyclic aromatic hydrocarbons (PAHs) from coal burning for industry and home heating. In experimental...
Oncogene activation in experimental carcinogenesis: the role of carcinogen and tissue specificity.
Techniques of molecular biology have been used to determine the relationship of cellular oncogenes to mechanisms of experimental carcinogenesis. Model systems involving three direct-acting alkylating...
Multiple stages in radiation carcinogenesis of rat skin.
Burns, F J, Albert, R E, Garte, S J
Epithelial cell cancers are induced in rat skin by ionizing radiation in a manner that is consistent with the dual action (i.e., two alterations) hypothesis of radiation effects on DNA. This...
Oncogenes and radiation carcinogenesis.
Current research indicates a role for several oncogenes in radiation-induced carcinogenesis in vivo and cell transformation in vitro. Certain oncogenes are probably also involved in some cases of...
Activation of c-myc and c-K-ras oncogenes in primary rat tumors induced by ionizing radiation.
Sawey, M J, Hood, A T, Burns, F J, Garte, S J
An activated K-ras oncogene was detected by transfection in NIH 3T3 cells and by Southern blot analysis in 6 of 12 rat skin tumors induced by ionizing radiation. The DNA from 10 of the 12 tumors also...
Transforming gene in human atherosclerotic plaque DNA.
Penn, A, Garte, S J, Warren, L, Nesta, D, Mindich, B
The monoclonal hypothesis equates atherosclerotic plaques with benign smooth muscle cell tumors and proposes that plaques can arise via mutational or viral events. Here, we provide direct evidence...
Relationship between ambient air pollution and DNA damage in Polish mothers and newborns.
Whyatt, R M, Santella, R M, Jedrychowski, W, Garte, S J, Bell, D A, Ottman, R, ...
Industrialized regions in Poland are characterized by high ambient pollution, including polycyclic aromatic hydrocarbons (PAHs) from coal burning for industry and home heating. In experimental...
Oncogene activation in experimental carcinogenesis: the role of carcinogen and tissue specificity.
Techniques of molecular biology have been used to determine the relationship of cellular oncogenes to mechanisms of experimental carcinogenesis. Model systems involving three direct-acting alkylating...
Multiple stages in radiation carcinogenesis of rat skin.
Burns, F J, Albert, R E, Garte, S J
Epithelial cell cancers are induced in rat skin by ionizing radiation in a manner that is consistent with the dual action (i.e., two alterations) hypothesis of radiation effects on DNA. This...
Oncogenes and radiation carcinogenesis.
Current research indicates a role for several oncogenes in radiation-induced carcinogenesis in vivo and cell transformation in vitro. Certain oncogenes are probably also involved in some cases of...