Comparative biliary excretion of cephalosporins in normal and partially hepatectomized rats.
Humphries, N L, Tasker, D G, Karran, S J
The biliary excretion of six cephalosporins was examined in normal and partially hepatectomized rats. Cefamandole, cefazolin, cefuroxime, cefoxitin, and cephradine were excreted well in normal...
Mackie, I J, Walshe, K, Cohen, H, McCarthy, P, Shearer, M, Scott, S D, ...
Two patients with low random serum vitamin K1 concentrations but with normal prothrombin times and normal biological assays of the vitamin K dependent coagulation proteins were treated with an...
Mortality in a university surgical unit: what is an avoidable death?
McDonald, P J, Royle, G T, Taylor, I, Karran, S J
Between January 1978 and December 1987 there were 23,557 surgical admissions to the University Surgical Unit in Southampton. During this period there were 543 deaths, an overall death per admission...
Comparative biliary excretion of cephalosporins in normal and partially hepatectomized rats.
Humphries, N L, Tasker, D G, Karran, S J
The biliary excretion of six cephalosporins was examined in normal and partially hepatectomized rats. Cefamandole, cefazolin, cefuroxime, cefoxitin, and cephradine were excreted well in normal...
Mackie, I J, Walshe, K, Cohen, H, McCarthy, P, Shearer, M, Scott, S D, ...
Two patients with low random serum vitamin K1 concentrations but with normal prothrombin times and normal biological assays of the vitamin K dependent coagulation proteins were treated with an...
Mortality in a university surgical unit: what is an avoidable death?
McDonald, P J, Royle, G T, Taylor, I, Karran, S J
Between January 1978 and December 1987 there were 23,557 surgical admissions to the University Surgical Unit in Southampton. During this period there were 543 deaths, an overall death per admission...
Relation of anthropometric and dynamometric variables to serious postoperative complications.
Klidjian, A M, Foster, K J, Kammerling, R M, Cooper, A, Karran, S J
Prediction of serious postoperative complications by using standard anthropometric and biochemical nutritional variables was attempted in 225 patients admitted for major abdominal surgery. In 102 of...
Observations on liver regeneration after right hepatic lobectomy
Blumgart, L. H., Leach, K. G., Karran, S. J.
Restoration of liver mass has been studied in five patients after right hepatic lobectomy. The operation effects an approximate 50% resection of liver substance. Postmortem observations, measurements...
Community surveillance of complications after hernia surgery.
Bailey, I. S., Karran, S. E., Toyn, K., Brough, P., Ranaboldo, C., Karran, S. J.
OBJECTIVE--To assess the effect of a programme of postoperative community surveillance on the rate of detection of wound complications after operation for inguinal hernia. DESIGN--Prospective audit...
Moran, B. J., Sutton, G. L., Karran, S. J.
A new, long-term venous access catheter was evaluated in clinical practice and the insertion time, complication rate and prospective follow-up recorded. Fifty novel polyurethane catheters (Cuff-Cath)...
Postoperative complications: how much do they cost?
De La Hunt, M. N., Chan, A. Y., Karran, S. J.
Complications following major abdominal surgery incur considerable expense. The aims of this study were to analyse prospectively the costs of complications following major abdominal surgery and to...
The practical management of Fournier's gangrene.
Scott, S. D., Dawes, R. F., Tate, J. J., Royle, G. T., Karran, S. J.
Effective early treatment of this serious condition is necessary to prevent death. Urgent exploration by the most experienced surgeon available should include wide excision of all necrotic or dubious...
The metabolic effects of moderately severe upper gastrointestinal haemorrhage in man.
Foster, K. J., Alberti, K. G., Binder, C., Holdstock, G., Karran, S. J., Smith, C. L., ...
The metabolic effects of moderately severe gastrointestinal haemorrhage were investigated in man. Before resuscitation, patients had raised circulating concentrations of glucose, lactate, alanine,...