S. J. Mackenzie

Publication List Details

Period

1993 - 2004

Number

22

Co-Authors

COMPARISON OF RECOVERY FROM ANAESTHESIA INDUCED IN CHILDREN WITH EITHER PROPOFOL OR THIOPENTONE (1993)

RUNCIE, C. J., MACKENZIE, S. J., ARTHUR, D. S., MORTON, N. S.

We studied 102 children undergoing day-case surgery, allocated randomly to receive either thio-pentone 5mgkg-1 or propofol 3mgkg-1 i.v. at induction of anaesthesia. They then inhaled nitrous oxide...

Acid--base responses to high-volume haemofiltration in the critically ill (1993)

Nimmo, G. R., Mackenzie, S. J., Walker, S., Nicol, M., Grant, I. S.

We have studied the acid-base and cardiorespiratory effects of intermittent pumped high-volume venovenous haemofiltration (HVHF) using replacement fluid containing lactate as the source of...

IgM monoclonal antibodies recognizing Fc alpha R but not Fc gamma RIII trigger a respiratory burst in neutrophils although both trigger an increase in intracellular calcium levels and degranulation.

Mackenzie, S J, Kerr, M A

The role of IgG receptor, Fc gamma RIII, in the triggering of neutrophil functions has been controversial. Here we show that IgM monoclonal antibodies, Leu 11b and 1D3, recognizing Fc gamma RIII,...

The MAP kinase ERK2 inhibits the cyclic AMP-specific phosphodiesterase HSPDE4D3 by phosphorylating it at Ser579.

Hoffmann, R, Baillie, G S, MacKenzie, S J, Yarwood, S J, Houslay, M D

The extracellular receptor stimulated kinase ERK2 (p42(MAPK))-phosphorylated human cAMP-specific phosphodiesterase PDE4D3 at Ser579 and profoundly reduced ( approximately 75%) its activity. These...

Protein kinase C isoforms play differential roles in the regulation of adipocyte differentiation.

Fleming, I, MacKenzie, S J, Vernon, R G, Anderson, N G, Houslay, M D, Kilgour, E

In this study we first established, by immunoblotting with specific antibodies, the temporal changes in cellular levels of protein kinase C (PKC) isoforms during differentiation of 3T3-F442A...

Action of rolipram on specific PDE4 cAMP phosphodiesterase isoforms and on the phosphorylation of cAMP-response-element-binding protein (CREB) and p38 mitogen-activated protein (MAP) kinase in U937 monocytic cells.

MacKenzie, S J, Houslay, M D

U937 monocytic cells are shown here to express a range of PDE4, cAMP-specific phosphodiesterase (PDE) isoenzymes: the long isoenzymes, PDE4A4, PDE4D5 and PDE4D3, plus the short isoenzyme, PDE4B2....

IgM monoclonal antibodies recognizing Fc alpha R but not Fc gamma RIII trigger a respiratory burst in neutrophils although both trigger an increase in intracellular calcium levels and degranulation.

Mackenzie, S J, Kerr, M A

The role of IgG receptor, Fc gamma RIII, in the triggering of neutrophil functions has been controversial. Here we show that IgM monoclonal antibodies, Leu 11b and 1D3, recognizing Fc gamma RIII,...

The MAP kinase ERK2 inhibits the cyclic AMP-specific phosphodiesterase HSPDE4D3 by phosphorylating it at Ser579.

Hoffmann, R, Baillie, G S, MacKenzie, S J, Yarwood, S J, Houslay, M D

The extracellular receptor stimulated kinase ERK2 (p42(MAPK))-phosphorylated human cAMP-specific phosphodiesterase PDE4D3 at Ser579 and profoundly reduced ( approximately 75%) its activity. These...

Protein kinase C isoforms play differential roles in the regulation of adipocyte differentiation.

Fleming, I, MacKenzie, S J, Vernon, R G, Anderson, N G, Houslay, M D, Kilgour, E

In this study we first established, by immunoblotting with specific antibodies, the temporal changes in cellular levels of protein kinase C (PKC) isoforms during differentiation of 3T3-F442A...

Action of rolipram on specific PDE4 cAMP phosphodiesterase isoforms and on the phosphorylation of cAMP-response-element-binding protein (CREB) and p38 mitogen-activated protein (MAP) kinase in U937 monocytic cells.

MacKenzie, S J, Houslay, M D

U937 monocytic cells are shown here to express a range of PDE4, cAMP-specific phosphodiesterase (PDE) isoenzymes: the long isoenzymes, PDE4A4, PDE4D5 and PDE4D3, plus the short isoenzyme, PDE4B2....