S. Janssens

and Process Control, (2009)

S. Janssens, Coupure Links, B. De Baets, H. De Meyer

Several meta-theorems are proposed which state that certain inequalities satisfied by cardinalities of ordinary sets, are preserved under fuzzification.

and Process Control, (2009)

H. De Meyer, B. De Baets, Coupure Links, S. Janssens

We outline a method for measuring in an efficient way an overall degree of similarity between different leaf-labelled trees. In particular, we consider rooted trees, either unordered or ordered and...

Emerging patterns of cryptic chromosomal imbalances in patients with idiopathic mental retardation and multiple congenital anomalies: a new series of 140 patients and review of the literature (2006)

Menten, B, Buysse, K, Vandesompele, Joke, ...

BACKGROUND: Chromosomal abnormalities are a major cause of mental retardation and multiple congenital anomalies (MCA/MR). Screening for these chromosomal imbalances has mainly been done by standard...

Signals from within: the DNA-damage-induced NF-kappaB response (2006)

Janssens, S, Tschopp, J

An appropriate response to genotoxic stress is essential for maintenance of genome stability and avoiding the passage to neoplasia. Nuclear factor kappaB (NF-kappaB) is activated as part of the DNA...

Autosomal dominant pseudohypoaldosteronism type 1: Mechanisms, evidence for neonatal lethality, and phenotypic expression in adults (2006)

Geller, DS, Zhang, JH, Zennaro, MC, Vallo-Boado, A, Rodriguez-Soriano, J, Furu, L, ...

Autosomal dominant pseudohypoaldosteronism type 1 (adPHA1) is a rare condition that is characterized by renal resistance to aldosterone, with salt wasting, hyperkalemia, and metabolic acidosis. It is...

Cardiomyocyte-restricted nitric oxide synthase 3 overexpression attenuates left ventricular remodeling in mice with chronic pressure overload (2005)

Jassal, DS, Buys, E, Neilan, TG, Raher, MJ, Ichinose, F, Janssens, S, ...

Increased cardiac expression of TIMP-1 and TIMP-2 is related to cardiac fibrosis and dysfunction in the chronic pressure-overloaded human heart (2005)

Heymans, Stephane; U0011145, Schroen, B, Milting, H, Herijgers, Paul; U0010444, Carmeliet, Peter; U0021003, Van De Werf, Frans; U0009589, ...

Increased cardiac expression of tissue inhibitor of metalloproteinase-1 and tissue inhibitor of metalloproteinase-2 is related to cardiac fibrosis and dysfunction in the chronic pressure-overloaded human heart (2005)

Heymans, Stephane; U0011145, Schroen, B, Vermeersch, Pieter; U0035259, Milting, H, Gao, FY, Kassner, A, ...

Background - Alterations in the balance of matrix metalloproteinases ( MMPs) and their specific tissue inhibitors (TIMPs) are involved in left ventricular (LV) remodeling. Whether their expression is...

Cardiomyocyte-restricted overexpression of the human eNOS gene significantly attenuates myocardial ischemia reperfusion injury (2005)

Elrod, JW, Greer, JJ, Wright, DG, Janssens, S, Lefer, DJ

Novel roles of plasmin, uPAR and suPAR in mobilization and retention of HSC/HPCs (2005)

Sidenius, N, Moura, R, Janssens, S, ...

Transplantation of autologous bone marrow-derived stem cells in patients with ST-segment elevation myocardial infarction (2005)

Janssens, S, Dubois, CL, Bogaert, Jan; U0008711, Theunissen, Koen; U0032192, Derooze, C, Kalantzis, M, ...

Cytochrome P450 Epoxygenase inhibition attenuates hypoxic pulmonary vasoconstriction and pulmonary vascular remodeling (2005)

Pokreisz, Peter; U0032789, Fleming, I, Kiss, L, Barbosa-Sicard, E, Fisslthaler, B, Falck, JR, ...

Cytochrone P450 epoxygenase inhibition attenuates hypoxia-induced pulmonary vasoconstriction and vascular remodeling in mice (2005)

Vermeersch, Pieter; U0035259, Szelid, Z, Falck, JR, Hammock, BD, Fleming, I, ...

Novel roles of plasmin, uPAR and suPAR in mobilization and retention of HSC/HPCs (2005)

Sidenius, N., Theunissen, Koen, Moura, R., Janssens, S., ...

Bell-type inequalities for quasi-copulas (2004)

Janssens, S, De Baets, B, De Meyer, H

We present all Bell-type inequalities regarding at most four random events of which not more than two are intersected at the same time. Reformulating these inequalities in the context of fuzzy...

Novel role of plasmin in mobilization and of uPAR in retention of hematopoietic stem/progenitor cells in the bone marrow niche: Therapeutic implications (2004)

Sidenius, N, Theunissen, K, Moura, R, Janssens, S, ...

Responsiveness to inhaled nitric oxide is a predictor for mid-term survival in adult patients with congenital heart defects and pulmonary arterial hypertension (2004)

Post, M C, Janssens, S, Van De Werf, Frans; U0009589, Budts, Werner; U0037749

BACKGROUND: It was previously demonstrated that in adults with congenital heart disease and pulmonary arterial hypertension and/or the Eisenmenger syndrome, the pulmonary circulation remained...

Conflicting phylogenies of balsaminoid families and the polytomy in Ericales: combining data in a Bayesian framework (2004)

Geuten, Koen; U0039927, Smets, Eric; U0012224, Schols, P, Yuan, Y-M, Janssens, S, Küpfer, P, ...

The balsaminoid Ericales, namely Balsaminaceae, Marcgraviaceae, Tetrameristaceae, and Pellicieraceae have been confidently placed at the base of Ericales, but the relations among these families have...

Cardiomyocyte-specific overexpression of nitric oxide synthase 3 improves left ventricular performance and reduces compensatory hypertrophy after myocardial infarction (2004)

Janssens, S, Schoonjans, Luc; U0009528, Pellens, Marijke; U0033117, Vermeersch, Pieter; U0035259, Tjwa, Marc; U0034792, ...

Nitric oxide ( NO) is an important modulator of cardiac performance and left ventricular (LV) remodeling after myocardial infarction (MI). We tested the effect of cardiomyocyte-restricted...

Responsiveness to inhaled nitric oxide is a predictor for mid-term survival in adult patients with congenital heart defects and pulmonary arterial hypertension (2004)

Post, M.C., Janssens, S., Budts, W.

Background It was previously demonstrated that in adults with congenital heart disease and pulmonary arterial hypertension and/or the Eisenmenger syndrome, the pulmonary circulation remained...

Cardiomyocyte-specific NOS3 Overexpression Protects Against Chronic Pressure Overload-induced LV Hypertrophy and Dysfunction (2004)

Janssens, S, Pellens, Marijke; U0033117, Vermeersch, Pieter; U0035259, Jans, P, Gillijns, Hilde; U0001751, ...

Novel role of plasmin in mobilization and of uPAR in retention of hematopoietic stem/progenitor cells in the bone marrow niche: therapeutic implications (2004)

Sidenius, N., Theunissen, K., Janssens, S., ...

Cardiomyocyte-restricted endothelial nitric oxide synthase overexpression impairs right ventricular remodeling in transgenic mice exposed to chronic hypoxia (2003)

Vermeersch, Pieter; U0035259, Szelid, Z, Gillijns, H, Pellens, Marijke; U0033117, Collen, Desire; U0016103, ...

Cardioselective nitric oxide synthase 3 gene transfer reduces endothelial activation, neutrophil infiltration and infarct size following myocardial ischemia-reperfusion injury in pigs (2003)

Szelid, Z, Vermeersch, Pieter; U0035259, Gillijns, H, Pellens, Marijke; U0033117, Sinnaeve, Peter; U0011642, ...

MyD88(S), a splice variant of MyD88, differentially modulates NF-kappa B- and AP-1-dependent gene expression (2003)

Janssens, S, Burns, K, Vercammen, E, Tschopp, J, Beyaert, R

MyD88 is an adapter protein that is involved in Toll-like receptor (TLR)- and interleukin-1 receptor (IL-1R)-induced activation of nuclear factor-kappaB (NF-kappaB) and c-Jun N-terminal kinase (JNK)....

Cardioselective nitric oxide synthase 3 gene transfer protects against myocardial ischemia-reperfusion injury in pigs (2003)

Szelid, Z, Sinnaeve, Peter; U0011642, Vermeersch, Pieter; U0035259, Gillijns, H, Pellens, Marijke; U0033117, Van Pelt, N, ...

Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members (2003)

Janssens, S, Beyaert, R

Interleukin-1 receptor-associated kinase (IRAK) was first described as a signal transducer for the proinflammatory cytokine interleukin-1 (IL-1) and was later implicated in signal transduction of...

Inhibition of interleukin 1 receptor/toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4 (2003)

Burns, K, Janssens, S, Brissoni, B, Olivos, N, Beyaert, R, Tschopp, J

Toll-like receptors (TLRs) and members of the proinflammatory interleukin 1 receptor (IL-1R) family are dependent on the presence of MyD88 for efficient signal transduction. The bipartite nature of...

A universal role for MyD88 in TLR/IL-1R-mediated signaling (2002)

Janssens, S, Beyaert, R

The MyD88 adapter protein links members of the toll-like receptor (TLR) and interleukin-1 receptor (IL-1R) superfamily to the downstream activation of nuclear factor-kappaB and mitogen-activated...

In vivo gene transfer of endothelial nitric oxide synthase decreases portal pressure in anaesthetised carbon tetrachloride cirrhotic rats (2002)

Van De Casteele, Marc; U0004468, Omasta, A, Janssens, S, Roskams, Tania; U0007204, Desmet, Valeer; U0011957, ...

BACKGROUND: Portal hypertension in cirrhosis results from enhanced intrahepatic resistance to an augmented inflow. The former is partly due to an imbalance between intrahepatic vasoconstriction and...

Regulation of interleukin-1-and lipopolysaccharide-induced NF-kappa B activation by alternative splicing of MyD88 (2002)

Janssens, S, Burns, K, Tschopp, J, Beyaert, R

MyD88 is an adaptor protein that is involved in interleukin-1 receptor (IL-1 R)- and Toll-like receptor (TLR)-induced activation of NF-kappaB [1-3]. It is composed of a C-terminal Toll/IL-IR homology...

Nitric Oxide and Apoptosis in Heart Failure (2002)

Janssens, S, Schoonjans, Luc; U0009528, Vermeersch, Pieter; U0035259, Tjwa, Marc; U0034792, Pellens, Marijke; U0033117, ...

Residual pulmonary vasoreactivity to inhaled nitric oxide in patients with severe obstructive pulmonary hypertension and Eisenmenger syndrome (2001)

Van Pelt, N, Gillyns, H, Gewillig, M, Janssens, S

OBJECTIVE: To determine whether inhaled NO (iNO) can reduce pulmonary vascular resistance in adults with congenital heart disease and obstructive pulmonary hypertension or Eisenmenger syndrome....

Overexpression of cytochrome P4502C9, an epoxygenase with hyperpolarizing activity, modulates pulmonary vascular tone in murine lungs (2001)

Vermeersch, Pieter; U0035259, Fisslthaler, B, Busse, R, Pellens, Marijke; U0033117, Van Pelt, N, ...

Overexpression of a mutant, cGMP-independent protein kinase reduces restenosis in stented porcine coronary arteries (2001)

Sinnaeve, Peter; U0011642, Gillijns, H, Van Pelt, N, Chiche, JD, Bloch, K, Collen, Desire; U0016103, ...

Hardware/Software Co-design of an elliptic curve public-key cryptosystem (2001)

Janssens, S, Thomas, J, Borremans, W, Gijsels, P, ...

\emph{IEEE 2001 Workshop on Signal Processing Systems : Design and Implementation (F. Catthoor, M. Moonen, eds.), (SIPS 2001)}, Antwerp, Belgium, Sep. 2001

Aerosol gene transfer with inducible nitric oxide synthase reduces hypoxic pulmonary hypertension and pulmonary vascular remodeling in rats (2000)

Budts, Werner; U0037749, Nong, ZX, Van Pelt, N, Gillijns, H, Gerard, R, ...

BACKGROUND: Nitric oxide (NO) is a potent vasodilator with an important role in the regulation of pulmonary vascular tone. The effects of NO synthase (NOS) gene transfer on pulmonary vascular...

Nitric oxide inhalation detects residual pulmonary vasoreactivity in patients with severe obstructive pulmonary hypertension and Eisenmenger syndrome (2000)

Budts, Werner; U0037749, Van Pelt, N, Gillyns, H, Van De Werf, Frans; U0009589, Janssens, S

Biological activity of hexitol nucleic acids targeted at Ha-ras and intracellular adhesion molecule-1 mRNA (2000)

Préveral, S, Janssens, S, Geysen, J, Saison-Behmoaras, E, ...

Hexitol nucleic acid (HNA) is a new steric blocking oligonucleotide, hybridizing sequence selectively with RNA. The biological activity of HNA was evaluated in an in vitro translation arrest system...

Gene therapy in the cardiovascular system: an update (1999)

Varenne, O, Janssens, S

This update reviews the remarkable progression in several cardiovascular gene transfer domains. The first chemical gene therapy protocols to stimulate angiogenesis in ischemic myocardium are...

Single bolus administration of polyethylene glycol-derivated cysteine-substitution variants of recombinant staphylokinase in acute myocardial infarction (1999)

Sinnaeve, Peter; U0011642, Janssens, S, Van De Werf, Frans; U0009589, Collen, Desire; U0016103

Overexpression of a constitutively-active cGMP-independent protein kinase mutant reduces neointima formation following balloon-injury in rat carotid arteries via an antiproliferative and antimigratory effect (1999)

Sinnaeve, Peter; U0011642, Gillijns, H, Van Peit, N, Chiche, JD, Collen, Desire; U0016103, Bloch, K, ...

Over-expression of nitric oxide synthase-3 (NOS-3) and free-radical injury cause apoptosis and phospho-tau accumulation in neuronal cells (1999)

De La Monte, SM, Ganju, N, Luong, T, Janssens, S, Bloch, KD, Feroz, N, ...

Adenovirus-mediated transfer of soluble guanylayte cyclase alpha 1 and beta 1 subunits increases nitric oxide responsiveness and reduces neointima formation in balloon-injured rat carotid arteries (1998)

Sinnaeve, Peter; U0011642, Chiche, JD, Nong, ZX, Varenne, O, Van Pelt, N, Gerard, RD, ...

Reduction of in-stent restenosis by adenoviral-mediated NOS3 gene transfer in porcine coronary arteries (1998)

Varenne, O, Gillijns, H, Gold, HK, Van De Werf, Frans; U0009589, Gerard, RD, Collen, Desire; U0016103, ...

Comparison of local delivery catheters for intracoronary gene transfer in pigs (1998)

Varenne, O, Gerard, RD, Sinnaeve, Peter; U0011642, Gillijns, H, Wauterickx, K, Van Pelt, N, ...

NO synthase in the liver: prospects of in vivo gene transfer (1998)

Janssens, S, ...

Laboratories of Hepatology, University Hospitals, Leuven, Belgium.

One more wage curve: the case of Belgium (1998)

Janssens, S, Konings, Jozef; U0017520

This paper estimates a wage curve for Belgium. We find an unemployment elasticity of pay close to - 0.1 for males, but none for females. This may indicate that the female workforce, unlike the male,...

Retinoic acid potentiates TNF-alpha-induced, but not IFN-gamma-induced ICAM-1 in both differentiated and undifferentiated keratinocytes (1998)

Janssens, S, Bols, L, Daneels, G, Vandermeeren, M, Borgers, M, Geysen, J

Comparison of recombinant adenovirus vectors expressing antimigratory and antiproliferative proteins in a porcine coronary restenosis model (1998)

Varenne, O, Sinnaeve, Peter; U0011642, Gillijns, H, Laurysens, Veerle; U0022303, Bout, A, Meurrens, K, ...

Inhibitory role of plasminogen activator inhibitor-1 in arterial wound healing and neointima formation: a gene targeting and gene transfer study in mice (1997)

Janssens, S, Lupu, F, ...

BACKGROUND: Plasminogen-deficient mice display impaired vascular wound healing and reduced arterial neointima formation after arterial injury, suggesting that inhibition of plasmin generation might...

Nitric oxide inhalation inhibits platelet aggregation and platelet-mediated pulmonary thrombosis in rats (1997)

VanPelt, N, Janssens, S

Endothelium-derived nitric oxide (NO) inhibits in vitro platelet aggregation via a cGMP-dependent mechanism. The effect of inhaled NO an platelet-mediated pulmonary thrombosis following intravenous...

Aerosol nitric oxide synthase gene transfer in acute hypoxic pulmonary hypertension (1997)

Budts, Werner; U0037749, Nong, ZX, VanPelt, N, Lyons, R, Gerard, RD, Janssens, S

Inhibition of platelet activation by pulmonary nitric oxide reduces vascular response to injury (1997)

Nong, Z, Varenne, O, Gerard, R, Collen, Desire; U0016103, Janssens, S

Dimethylfumarate is an inhibitor of cytokine-induced VCAM-1, ICAM-1 and E-selectin expression on human endothelial cells (1997)

Vandermeeren, M, Janssens, S, Geysen, J, Borgers, M

In vivo gene transfer of NO synthase reduces portal pressure in experimental cirrhosis in rats (1996)

Van De Casteele, Marc; U0004468, Janssens, S, Roskams, Tania; U0007204, Desmet, Valeer; U0011957, Fevery, Johan; U0018702

Mechanism of theophylline-induced inotropic effects on foreshortened canine diaphragm (1996)

Janssens, S

The mechanisms of theophylline-induced inotropic effects at shorter diaphragm length have not yet been explored. We wondered whether the greater inotropic effects of the drug at shorter diaphragm...

Homogeneous myocardial expression of human constitutive nitric-oxide synthase by adenoviral gene-transfer during syngeneic heterotopic heart-transplantation (1995)

Janssens, S, Lin, Y, Nong, Zx, Zoldhelyi, P, Collen, Desire; U0016103, Waer, Mark; U0007319

Accelerated thrombin generation during conjunctive treatment of myocardial-infarction with t-pa and r-hirudin (cgp-39-393) (1995)

Zoldhelyi, P, Janssens, S, Lefevre, G, Collen, Desire; U0016103, Van De Werf, Frans; U0009589

Hypoxic pulmonary-hypertension in transgenic mice with loss of plasminogen-activator and plasminogen-activator inhibitor gene-function (1995)

Janssens, S, Nong, Zx, Stassen, Jm, Carmeliet, Peter; U0021003, Collen, Desire; U0016103

Inotropic effects of aminophylline on canine diaphragm are enhanced by hyperinflation (1994)

Palecek, F, Janssens, S

During acute hyperinflation, patients with chronic obstructive pulmonary disease are likely to have foreshortened inspiratory muscles. Because the effects of aminophylline on contractile properties...

Effects of theophylline (T) on diaphragmatic contractility in dogs (1990)

Janssens, S

Respiratory Division, University Hospitals, Katholieke Universiteit Leuven, Belgium.

Corticosteroid-induced myopathy and the respiratory muscles. Report of two cases (1989)

Janssens, S, Decramer, Marc; U0004666

Two women with connective tissue disease developed a characteristic steroid-induced myopathy. Reduced maximal transrespiratory pressures indicated reduced respiratory muscle strength. Gradual steroid...

Theophylline and the respiratory muscles - where are we (1989)

Decramer, Marc; U0004666, Janssens, S

Respiratory Division, University Hospitals, Katholieke Universiteit, Leuven, Belgium.