S. K. Sharma

Publication List Details

Period

1974 - 2008

Number

51

Co-Authors

Field Evaluation of a Previously Untested Strain of Biolarvicide (Bacillus thuringiensis israelensis H14) for Mosquito Control in an Urban Area of Orissa, India (2008)

S.K. Sharma, A.K. Upadhyay, M.A. Haque, K. Raghavendra, A.P. Dash

A previously untested strain of Bacillus thuringiensis israelensis (Bti) serotype H14 (ID No. VCRC B17) has been evaluated under field conditions in an urban area of Rourkela city, India for its...

Immune reconstitution inflammatory syndrome in a patient with cryptococcal lymphadenitis as the first presentation of acquired immunodeficiency syndrome (2008)

Tahir, M., Sharma, S.K., Sinha, S., Das, C.J.

Immune reconstitution inflammatory syndrome is commonly seen in acquired immunodeficiency syndrome (AIDS) patients having concomitant opportunistic infection, following initiation of highly active...

Clearance mechanism of a mannosylated antibody-enzyme fusion protein used in experimental cancer therapy (2007)

Kogelberg, H., Tolner, B., Sharma, S.K., Lowdell, M.W., Qureshi, U., Robson, M., ...

MFECP1 is a mannosylated antibody–enzyme fusion protein used in antibody-directed enzyme prodrug therapy (ADEPT). The antibody selectively targets tumor cells and the targeted enzyme converts a...

A phase I study of single administration of antibody-directed enzyme prodrug therapy with the recombinant anti-carcinoembryonic antigen antibody-enzyme fusion protein MFECP1 and a bis-iodo phenol mustard prodruga (2006)

Mayer, A., Francis, R.J., Sharma, S.K., Tolner, B., Springer, C.J., Martin, J., ...

Purpose: Antibody-directed enzyme prodrug therapy is a two-stage treatment whereby a tumor-targeted antibody-enzyme complex localizes in tumor for selective conversion of prodrug. The purpose of this...

Plate-concrete interfacial bond strength of FRP and metallic plated concrete specimens (2006)

Sharma, S. K., Goldar, D., Sikdar, P. K.

Bonding of steel or fibre reinforced polymer (FRP) plates by adhesive to the surface of concrete structural elements have become increasingly popular for improving their strength and stiffness....

Plate-concrete interfacial bond strength of FRP and metallic plated concrete specimens (2006)

Sharma, S. K., Goldar, D., Sikdar, P. K.

Bonding of steel or fibre reinforced polymer (FRP) plates by adhesive to the surface of concrete structural elements have become increasingly popular for improving their strength and stiffness....

Sustained tumor regression of human colorectal cancer xenografts using a multifunctional mannosylated fusion protein in antibody-directed enzyme prodrug therapy (2005)

Sharma, S.K., Pedley, R.B., Bhatia, J., Boxer, G.M., El-Emir, E., Qureshi, U., ...

Purpose: Antibody-directed enzyme prodrug therapy (ADEPT) requires highly selective antibody-mediated delivery of enzyme to tumor. MFE-CP, a multifunctional genetic fusion protein of antibody and...

Modifying an immunogenic epitope on a therapeutic protein: a step towards an improved system for antibody-directed enzyme prodrug therapy (ADEPT) (2004)

Mayer, A., Sharma, S.K., Tolner, B., Minton, N.P., Purdy, D., Amlot, P., ...

Carboxypeptidase G2 (CP) is a bacterial enzyme, which is targeted to tumours by an antitumour antibody for local prodrug activation in antibody-directed enzyme prodrug therapy (ADEPT). Repeated...

Glycoforms obtained by expression in Pichia pastoris improve cancer targeting potential of a recombinant antibody-enzyme fusion protein (2004)

Medzihradszky, K.F., Spencer, D.I.R., Sharma, S.K., Bhatia, J., Pedley, R.B., Read, D.A., ...

MFE-CP is a recombinant antibody-enzyme fusion protein used for antibody-mediated delivery of an enzyme to cancer deposits. After clearance from normal tissues, the tumortargeted enzyme is used to...

Diffusion in metallic glasses and supercooled melts (2003)

Faupel, F., Frank, W., Mehrer, H., Naundorf, V., Rätzke, K., ...

This version is available at the following Publisher URL: http://rmp.aps.org

A strategy for mapping and neutralizing conformational immunogenic sites on protein therapeutics (2002)

Spencer, D.I.R., Robson, L., Purdy, D., Whitelegg, N.R., Michael, N.P., Bhatia, J., ...

Antibodies are highly specific recognition molecules which are increasingly being applied to target therapy in patients. One type of developmental antibody-based therapy is antibody directed enzyme...

DNA sequence recognition in the minor groove by crosslinked polyamides: the effect of N-terminal head group and linker length on binding affinity and specificity (2002)

O'Hare, C.C., Mack, D., Tandon, M., Sharma, S.K., Lown, J.W., Kopka, M.L., ...

Development of sequence-reading polyamides or "lexitropsins" with comparable DNA-binding affinities to cellular proteins raises the possibility of artificially regulated gene expression. Covalent...

Adsorptive iron removal from groundwater (2001)

Sharma, S.K.

http://library.wur.nl/wda/abstracts/ab3119.html

Pachmarhi array of Cerenkov telescopes (2000)

Bhat, P. N, Acharya, B. S, Chitnis, V. R., D' Souza, A. I, Francis, P. J, Gothe, K. S, ...

Pachmarhi Array of Cerenkov Telescopes (PACT) consisting of 25 telescopes has been installed at Pachmarhi (longitude : 76d 26' E, latitude : 22d 28' N and altitude : 1075m) recently. The telescopes...

Serum adenosine deaminase (ADA) in differential diagnosis of pulmonary tuberculosis and no tubercular respiratory diseases (1988)

Jhamaria, J.H., Jenaw, R.K., Luhda, S.K., Mathur, D.K., Parihar, H.L., Sharma, S.K.

Serum adenosine deaminase (ADA) levels were determined in 20 healthy controls, 102 cases of pulmonary tuberculosis, 20 cases of suppurative lung diseases (Lung abscess and bronchiectasis 10 each) and...

Time-on-task in the learning process an empirical investigation of the effects of alterable variables on cognitive achievement (1981)

Sharma, S. K. (Surander Kumar)

Submitted to the Faculty of Education in candidacy for the degree of Doctor of Philosophy. Summary: leaves xviii-xx. Microreproduction of original issued: [Clayton, Vic.], 1981. xxii, 566 leaves....

Time-on-task in the learning process an empirical investigation of the effects of alterable variables on cognitive achievement (1981)

Sharma, S. K. (Surander Kumar)

A dissertation submitted to the Faculty of Education in candidacy for the degree of Doctor of Philosophy. Summary: p.xviii-xx. Typescript. Bibliography: p.539-566.

The effects of guidance and repetition on achievements, transfer and retention following programmed learning on the gas laws (1974)

Sharma, S. K. (Surander Kumar)

Submitted to the Faculty of Education in candidacy for the degree of Doctor of Philosophy. Summary: xviii-xx. Typescript. Includes bibliographical references (leaves 539-566)

Defined neurofilament, tau, and beta-amyloid precursor protein epitopes distinguish Alzheimer from non-Alzheimer senile plaques.

Arai, H, Lee, V M, Otvos, L, Greenberg, B D, Lowery, D E, Sharma, S K, ...

Eight antisera and one monoclonal antibody to synthetic peptides that corresponded to domains extending over the entire length of the beta-amyloid precursor protein (beta-APP), and an antiserum to...

Molecular Characterization of Multidrug-Resistant Isolates of Mycobacterium tuberculosis from Patients in North India

Siddiqi, Noman, Shamim, Mohammed, Hussain, Seema, Choudhary, Rakesh Kumar, Ahmed, Niyaz, ...

The World Health Organization has identified India as a major hot-spot region for Mycobacterium tuberculosis infection. We have characterized the sequences of the loci associated with multidrug...

Plasmodium falciparum Infection Elicits Both Variant-Specific and Cross-Reactive Antibodies against Variant Surface Antigens

Chattopadhyay, Rana, Sharma, Amit, Srivastava, Vinod K., Pati, Sudhanshu S., Sharma, S. K., Das, Bhabani S., ...

Naturally acquired antibodies to Plasmodium falciparum erythrocyte membrane protein-1 (PfEMP-1), the variant surface antigens expressed on the surface of infected erythrocytes, are thought to play a...

Identification of a cyclin-cdk2 recognition motif present in substrates and p21-like cyclin-dependent kinase inhibitors.

Adams, P D, Sellers, W R, Sharma, S K, Wu, A D, Nalin, C M, Kaelin, W G

Understanding how cyclin-cdk complexes recognize their substrates is a central problem in cell cycle biology. We identified an E2F1-derived eight-residue peptide which blocked the binding of cyclin A...

Opiate-dependent modulation of adenylate cyclase.

Sharma, S K, Klee, W A, Nirenberg, M

Reactions mediated by the opiate receptors that inhibit adenylate cyclase (EC 4.6.1.1) are closely coupled to subsequent reactions that gradually increase adenylate cyclase activity of neuroblastoma...

Morphine receptors as regulators of adenylate cyclase activity.

Sharma, S K, Nirenberg, M, Klee, W A

Morphine inhibits adenylate cyclase (EC 4.6.1.1) activity of neuroblastoma times glioma hybrid cells. The inhibition is stereospecific and is reversed by the antagonist, naloxone. The relative...

Dual regulation of adenylate cyclase accounts for narcotic dependence and tolerance.

Sharma, S K, Klee, W A, Nirenberg, M

Narcotics affect adenylate cyclase [ATP pyrophosphate-lyase (cyclizing), EC 4.6.1.1] in two opposing ways, both mediated by the opiate receptor. The first process is the readily reversible inhibition...

Molecular Genotyping of a Large, Multicentric Collection of Tubercle Bacilli Indicates Geographical Partitioning of Strain Variation and Has Implications for Global Epidemiology of Mycobacterium tuberculosis

Ahmed, Niyaz, Alam, Mahfooz, Rao, K. Rajender, Kauser, Farhana, Kumar, N. Ashok, Qazi, Nazia N., ...

Tuberculosis continues to be a major killer disease, despite an all-out effort launched against it in the postgenomic era. We describe here the population structure of Mycobacterium tuberculosis...

Studies on the effects of total nephrectomy in sheep.

Singh, J, Singh, A P, Peshin, P K, Singh, M, Sharma, S K

Effects of total nephrectomy were studied in six sheep. There was no marked deterioration in the clinical condition of the animals except anorexia and reduced water intake. Three sheep survived the...

A haemodynamic and radionuclide assessment of diltiazem in coronary heart disease.

Silke, B, Sharma, S K, Verma, S P, Midtbo, K A, Reynolds, G, Taylor, S H

To obtain multiple dose-response haemodynamic and radionuclide data on i.v. diltiazem, 12 ischaemic patients were studied during routine catheterization. At rest, following a 20 min stable control...

Human immunodeficiency virus type-1 reverse transcriptase and ribonuclease H as substrates of the viral protease.

Tomasselli, A. G., Sarcich, J. L., Barrett, L. J., Reardon, I. M., Howe, W. J., Evans, D. B., ...

A study has been made of the susceptibility of recombinant constructs of reverse transcriptase (RT) and ribonuclease H (RNase H) from human immunodeficiency virus type 1 (HIV-1) to digestion by the...

Post-Coital Antifertility Activity of Hibiscus rosa-sinensis Linn. roots

Vasudeva, Neeru, Sharma, S. K.

Ancient literature mentions the use of a number of plants/preparations for fertility regulation. Some local contraceptive agents have also been described in Ayurvedic and Unani texts. Documented...

Mediastinal paraganglioma presenting as an intracardiac mass with superior vena caval obstruction.

Sharma, S K, Sharma, S, Mukhopadhyay, S

A case of mediastinal paraganglioma presenting with superior vena caval obstruction is reported. The tumour extended into the right atrium and ventricle. Tru-Cut biopsy under ultrasonographic...

Subdural haematoma and the malfunctioning shunt.

Moussa, A H, Sharma, S K

Of 30 consecutive children with hydrocephalus treated by shunt implant, six developed subdural haematoma. Four of them presented with a malfunctioning shunt, and the diagnoses in all six cases were...

Atrial septal defect presenting as recurrent primary amoebic lung abscess.

Sharma, M., Mehta, H., Sharma, S. K.

A middle-aged female with an atrial septal defect (secundum type) presented with a primary pulmonary amoebic abscess. She was successfully treated with antiamoebic therapy. One year later she...

Mediastinal carcinoid tumour with unusual manifestations.

Aggarwal, P., Sharma, S. K., Chattopadhyay, T. K., Mukhopadhyay, A. K.

A rare case of mediastinal carcinoid tumour with superior vena cava obstruction, and osteolytic as well as osteoblastic secondaries in the bones is described. The relevant literature is reviewed.

Malignant fibrous histiocytoma of the mediastinum.

Aggarwal, P., Sharma, S. K., Dey, A. B., Chattopadhyay, T. K., Mathur, M.

A case of malignant fibrous histiocytoma of the mediastinum presenting with unusual features of fever and leucocytosis is reported. This is the youngest patient reported in the literature who had...