Significance of human testicular mast cells and their subtypes in male infertility (2000)
Yamanaka, K., Fujisawa, M., Tanaka, H., Okada, H., Arakawa, S., Kamidono, S.
The mast cell populations in the human testis were examined using immunohistochemical techniques in five fertile volunteers and 12 patients with obstructive azoospermia, seven patients with...
Telomerase activity in the testis of infertile patients with selected causes (1998)
Fujisawa, M, Tanaka, H, Tatsumi, N, Okada, H, Arakawa, S, Kamidono, S
Maeda, H, Fujii, A, Nakata, K, Arakawa, S, Kamidono, S
The in vitro activities of three newly developed quinolone drugs (T-3262, NY-198, and fleroxacin [AM-833; RO 23-6240]) against 10 strains of clinically isolated Chlamydia trachomatis were assessed...
Nakata, K, Maeda, H, Fujii, A, Arakawa, S, Umezu, K, Kamidono, S
Sparfloxacin was more potent than other quinolones (tosufloxacin, lomefloxacin, ciprofloxacin, ofloxacin, fleroxacin, enoxacin, and norfloxacin) and as potent as minocycline and doxycycline in...
Maeda, H, Fujii, A, Nakata, K, Arakawa, S, Kamidono, S
The in vitro activities of three newly developed quinolone drugs (T-3262, NY-198, and fleroxacin [AM-833; RO 23-6240]) against 10 strains of clinically isolated Chlamydia trachomatis were assessed...
Nakata, K, Maeda, H, Fujii, A, Arakawa, S, Umezu, K, Kamidono, S
Sparfloxacin was more potent than other quinolones (tosufloxacin, lomefloxacin, ciprofloxacin, ofloxacin, fleroxacin, enoxacin, and norfloxacin) and as potent as minocycline and doxycycline in...
Gohji, K., Nakajima, M., Boyd, D., Dinney, C. P., Bucana, C. D., Kitazana, S., ...
We examined the role of urokinase-type plasminogen activator (u-PA) in the metastasis of the human renal cell carcinoma (HRCC) implanted in athymic nude mice. Cells from a HRCC KG-2 line were...
Expression patterns of CD44 adhesion molecule in testicular germ cell tumors and normal testes.
Miyake, H., Hara, I., Yamanaka, K., Gohji, K., Arakawa, S., Kamidono, S.
Despite recent extensive immunohistochemical studies, the expression patterns of CD44 in testicular germ cell tumors are still controversial. In the present study, we investigated the CD44 gene...
Shirakawa, J., Nakanishi, T., Taniyama, K., Kamidono, S., Tanaka, C.
1. The action of substance P (SP) on the release of gamma-aminobutyric acid (GABA) and acetylcholine (ACh) and on contraction were studied in strips of the guinea-pig urinary bladder. Substance P...
Shigemura, K, Okada, H, Shirakawa, T, Tanaka, K, Arakawa, S, Kinoshita, S, ...
Objectives: Decreasing susceptibility of Neisseria gonorrhoeae to fluoroquinolones has been reported in several countries. Knowledge of local N gonorrhoeae susceptibilities to various antimicrobials...
Overexpression of Bcl-2 enhances metastatic potential of human bladder cancer cells
Miyake, H, Hara, I, Yamanaka, K, Gohji, K, Arakawa, S, Kamidono, S
We investigated the effect of Bcl-2 expression on the metastatic process of bladder cancer cells by using the Bcl-2-transfected human bladder cancer cell lines (KoTCC-1/BH) and the control vector...
Miyake, H, Hara, S, Arakawa, S, Kamidono, S, Hara, I
Although numerous chemotherapeutic agents have been evaluated for patients with advanced prostate cancer, none have demonstrated improved survival benefits. Here, in order to determine whether the...