Scientific Commons: S. Kirchhoff

Cardiomyocyte-restricted deletion of Connexin43 during mouse development (2006)

Eckardt, D., Kirchhoff, S., Kim, J.S., Degen, J., Theis, M., Ott, T., ...

Although the gap junction protein Connexin43 (Cx43) is expressed in various cell types during embryonic development, mice with a global inactivation of Cx43 survive until birth but die perinatally...

Recent methodologies for in situ water quality monitoring associated with marine biotoxins and toxic algal blooms (2005)

Cembella, A. D., Quilliam, M., Lewis, N., Ibarra, D., Rafuse, C., Jellett, J., ...

Strategies for in situ detection of harmful algal blooms and their toxins in coastal waters (2003)

Cembella, A., Quilliam, M. A., Lewis, N., Ibarra, D., Rafuse, C., Jellett, J., ...

Viral IFN-regulatory factors inhibit activation-induced cell death via two positive regulatory IFN-Regulatory factor 1- dependent domains in the CD95 ligand promoter (2002)

Kirchhoff,S., Sebens,T., Baumann,S., Krueger,A., Zawatzky,R., Min,L. W., ...

The CD95 (also called APO-1/Fas) system plays a major role in the induction of apoptosis in lymphoid and nonlymphoid tissues. The CD95 ligand (CD95L) is induced in response to a variety of signals,...

Viral IFN-regulatory factors inhibit activation-induced cell death via two positive regulatory IFN-Regulatory factor 1- dependent domains in the CD95 ligand promoter (2002)

Kirchhoff, S., Sebens, T., Baumann, S., Krueger, A., Zawatzky, R., Min, L. W., ...

The CD95 (also called APO-1/Fas) system plays a major role in the induction of apoptosis in lymphoid and nonlymphoid tissues. The CD95 ligand (CD95L) is induced in response to a variety of signals,...

Defective vascular development in connexin 45-deficient mice (2000)

Kruger, O., Plum, A., Kim, J.S., Winterhager, E., Maxeiner, S., Hallas, G., ...

Abnormal cardiac conduction and morphogenesis in Connexin40 and Connexin43 double-deficient mice (2000)

Kirchhoff, S., Kim, J.S., Hagendorff, A., Thonnissen, E., Kruger, O., Lamers, W.H., ...

Interferon regulatory factor 1 (IRF-1) mediates cell growth inhibition by transactivation of downstream target genes.

Kirchhoff, S, Schaper, F, Hauser, H

Interferon regulatory factor 1 (IRF-1) is a DNA-binding factor which recognizes regulatory elements in the promoters of interferon (IFN)-beta and some IFN-inducible genes. We observed that expression...

The protein sequence and some intron positions are conserved between the switching gene swi10 of Schizosaccharomyces pombe and the human excision repair gene ERCC1.

Rödel, C, Kirchhoff, S, Schmidt, H

The switching gene swi10+ has a function in mating-type switching as well as in the repair of radiation damages. We have cloned the genomic swi10+ gene by functional complementation of the switching...

The rad16 gene of Schizosaccharomyces pombe: a homolog of the RAD1 gene of Saccharomyces cerevisiae.

Carr, A M, Schmidt, H, Kirchhoff, S, Muriel, W J, Sheldrick, K S, Griffiths, D J, ...

The rad10, rad16, rad20, and swi9 mutants of the fission yeast Schizosaccharomyces pombe, isolated by their radiation sensitivity or abnormal mating-type switching, have been shown previously to be...

Physical association between STAT1 and the interferon-inducible protein kinase PKR and implications for interferon and double-stranded RNA signaling pathways.

Wong, A H, Tam, N W, Yang, Y L, Cuddihy, A R, Li, S, Kirchhoff, S, ...

The interferon-inducible double-stranded RNA protein kinase PKR controls protein synthesis through the phosphorylation of eukaryotic translation initiation factor (eIF)-2. In addition to its...

Functional domains of interferon regulatory factor I (IRF-1).

Schaper, F, Kirchhoff, S, Posern, G, Köster, M, Oumard, A, Sharf, R, ...

Interferon (IFN) regulatory factors (IRFs) are a family of transcription factors among which are IRF-1, IRF-2, and IFN consensus sequence binding protein (ICSBP). These factors share sequence...