S. Kitano

Publication List Details

Period

1998 - 2006

Number

58

Co-Authors

Porphyromonas gingivalis fimbria-stimulated bone resorption in vitro is inhibited by a tyrosine kinase inhibitor.

Hanazawa, S, Kawata, Y, Murakami, Y, Naganuma, K, Amano, S, Miyata, Y, ...

Our previous study (Y. Kawata, S. Hanazawa, S. Amano, Y. Murakami, T. Matsumoto, K. Nishida, and S. Kitano, Infect. Immun. 62:3012-3016, 1994) showed that Porphyromonas gingivalis fimbriae stimulate...

Porphyromonas gingivalis fimbrillin is one of the fibronectin-binding proteins.

Murakami, Y, Iwahashi, H, Yasuda, H, Umemoto, T, Namikawa, I, Kitano, S, ...

In this study, we demonstrate that Porphyromonas gingivalis fimbrillin, a major component of bacterial fimbriae, is one of the fibronectin-binding proteins and that fibronectin is a potent inhibitor...

CD14-mediated signal pathway of Porphyromonas gingivalis lipopolysaccharide in human gingival fibroblasts.

Watanabe, A, Takeshita, A, Kitano, S, Hanazawa, S

Lipopolysaccharide (LPS) induces expression of inflammatory cytokines in monocytes/macrophages via CD14, one of the LPS receptors, which is expressed predominantly in these cells. It has been...

Porphyromonas gingivalis lipopolysaccharide-stimulated bone resorption via CD14 is inhibited by broad-spectrum antibiotics.

Miyata, Y, Takeda, H, Kitano, S, Hanazawa, S

In the present study, we examined mechanisms of Porphyromonas gingivalis lipopolysaccharide (P-LPS)-stimulated bone resorption via CD14, one of the lipopolysaccharide (LPS) receptors, and also...

Porphyromonas gingivalis fimbria-stimulated bone resorption is inhibited through binding of the fimbriae to fibronectin.

Kawata, Y, Iwasaka, H, Kitano, S, Hanazawa, S

Our most recent study demonstrated that fibronectin is one of the Porphyromonas gingivalis fimbria-binding proteins. In this present study, we demonstrate with mouse embryonic calvarial cells that P....

Porphyromonas gingivalis fimbriae induce expression of the neutrophil chemotactic factor KC gene of mouse peritoneal macrophages: role of protein kinase C.

Hanazawa, S, Murakami, Y, Takeshita, A, Kitami, H, Ohta, K, Amano, S, ...

To account for infiltration of the periodontal tissues by neutrophils, the present study was undertaken to examine whether Porphyromonas gingivalis fimbriae, important structures involved in...

Bacteroides (Porphyromonas) gingivalis fimbriae activate mouse peritoneal macrophages and induce gene expression and production of interleukin-1.

Hanazawa, S, Murakami, Y, Hirose, K, Amano, S, Ohmori, Y, Higuchi, H, ...

The purpose of this study was to examine whether Bacteroides (Porphyromonas) gingivalis fimbriae, an important structure involved in attachment of the bacteria to periodontal tissues, activate...

Monoclonal antibody against a serotype antigen of Porphyromonas (Bacteroides) endodontalis and characteristics of the antigen.

Hanazawa, S, Sagiya, T, Amano, S, Nishikawa, H, Kitano, S

Recent studies have demonstrated the presence of three serotypes (O1K1, O1K2, and O1K-) of Porphyromonas (Bacteroides) endodontalis. In the present study, a hybridoma cell line producing monoclonal...

Bacteroides gingivalis fimbriae stimulate production of thymocyte-activating factor by human gingival fibroblasts.

Hanazawa, S, Hirose, K, Ohmori, Y, Amano, S, Kitano, S

In a previous report (Y. Ohmori, S. Hanazawa, S. Amano, T. Miyoshi, K. Hirose, and S. Kitano, infect. Immun. 55:947-954, 1987), we showed that human gingival fibroblasts spontaneously produce...

Spontaneous production of thymocyte-activating factor by human gingival fibroblasts and its autoregulatory effect on their proliferation.

Ohmori, Y, Hanazawa, S, Amano, S, Miyoshi, T, Hirose, K, Kitano, S

The purpose of this study was to examine whether human gingival fibroblasts produce a cytokine which modulates in immune and inflammatory responses including alterations in connective tissue...

Humoral antibody response against Bacteroides gingivalis-specific antigen recognized by monoclonal antibody in adult periodontal patients.

Miyoshi, T, Hanazawa, S, Hirose, K, Saitoh, K, Amano, S, Ohmori, Y, ...

An antigen recognized by monoclonal antibody specific for Bacteroides gingivalis was purified in the presence of 0.5% (wt/vol) beta-octyl-glucoside by immunoadsorbent column chromatography. The...

Production of monoclonal antibodies that recognize specific and cross-reactive antigens of Bacteroides gingivalis.

Hanazawa, S, Saitoh, K, Ohmori, Y, Nishihara, H, Fujiwara, S, Kitano, S

Four monoclonal antibodies directed against Bacteroides gingivalis were established by hybridoma technology. Their reactivity against B. gingivalis, Bacteroides intermedius, and Bacteroides...

Functional role of interleukin 1 in periodontal disease: induction of interleukin 1 production by Bacteroides gingivalis lipopolysaccharide in peritoneal macrophages from C3H/HeN and C3H/HeJ mice.

Hanazawa, S, Nakada, K, Ohmori, Y, Miyoshi, T, Amano, S, Kitano, S

Hot phenol-water-extracted lipopolysaccharide (LPS) from Bacteroides gingivalis 381 was purified by Sephadex G-100 chromatography with Tris buffer supplemented with sodium deoxycholate and EDTA...

Application of monoclonal antibodies to the detection of black-pigmented Bacteroides spp. in subgingival plaques by immunoslot blot assay.

Hanazawa, S, Tanaka, S, Kin, M, Amano, S, Nakada, K, Masuda, T, ...

The aim of the present study was to assess the application of monoclonal antibodies to the detection of black-pigmented Bacteroides spp. in subgingival plaques by immunoslot blot assay. Subgingival...

Monoclonal antibody against Porphyromonas (Bacteroides) endodontalis lipopolysaccharide and application of the antibody for direct identification of the species.

Hanazawa, S, Sagiya, T, Kitami, H, Ohta, K, Nishikawa, H, Kitano, S

The aim of the present study was to develop a monoclonal antibody that recognizes the shared antigen of Porphyromonas endodontalis so that we could use the antibody in direct identification and...

Expression of monocyte chemoattractant protein 1 (MCP-1) in adult periodontal disease: increased monocyte chemotactic activity in crevicular fluids and induction of MCP-1 expression in gingival tissues.

Hanazawa, S, Kawata, Y, Takeshita, A, Kumada, H, Okithu, M, Tanaka, S, ...

The present study shows that monocyte chemotactic activity in crevicular fluids increases with severity of the disease and that a monocyte chemoattractant, monocyte chemoattractant protein 1 (MCP-1),...

Nitric oxide mediates cytotoxicity and basic fibroblast growth factor release in cultured vascular smooth muscle cells. A possible mechanism of neovascularization in atherosclerotic plaques.

Fukuo, K, Inoue, T, Morimoto, S, Nakahashi, T, Yasuda, O, Kitano, S, ...

To define the pathophysiological role of nitric oxide (NO) released from vascular smooth muscle cells (VSMC), we examined whether NO released from VSMC induces cytotoxicity in VSMC themselves and...

Porphyromonas gingivalis fimbriae stimulate bone resorption in vitro.

Kawata, Y, Hanazawa, S, Amano, S, Murakami, Y, Matsumoto, T, Nishida, K, ...

Our previous study demonstrated that Porphyromonas gingivalis fimbriae induce the expression of interleukin-1, a potent bone-resorbing cytokine, in macrophages. This demonstration suggested to use...

Porphyromonas gingivalis fimbriae induce a 68-kilodalton phosphorylated protein in macrophages.

Murakami, Y, Hanazawa, S, Watanabe, A, Naganuma, K, Iwasaka, H, Kawakami, K, ...

The present study was performed to examine whether Porphyromonas gingivalis fimbriae induce specifically a protein kinase-mediated phosphorylated protein that is involved in the mechanism of signal...

Nucleotides. VI. Syntheses and spectral properties of some deazaadenylyl-deazaadenosines (dinucleoside monophosphates with unusual CD-spectrum) and closely related dinucleoside monophosphates.

Mizuno, Y, Kitano, S, Nomura, A

Nine dinucleoside phosphates containing 1-deaza-(1A) and 3-deazaadenosine (3A) were prepared. Hypochromicity and CD spectra of these dimers were determined. It was found that varying degrees of...

Quality of life after laparoscopy-assisted Billroth I gastrectomy.

Adachi, Y, Suematsu, T, Shiraishi, N, Katsuta, T, Morimoto, A, Kitano, S, ...

OBJECTIVE: To evaluate the quality of life of patients who had undergone laparoscopy-assisted Billroth I gastrectomy (LAG) for cure of cancer. SUMMARY BACKGROUND DATA: In 1994, the authors reported...

Porphyromonas gingivalis fimbria-stimulated bone resorption in vitro is inhibited by a tyrosine kinase inhibitor.

Hanazawa, S, Kawata, Y, Murakami, Y, Naganuma, K, Amano, S, Miyata, Y, ...

Our previous study (Y. Kawata, S. Hanazawa, S. Amano, Y. Murakami, T. Matsumoto, K. Nishida, and S. Kitano, Infect. Immun. 62:3012-3016, 1994) showed that Porphyromonas gingivalis fimbriae stimulate...

Porphyromonas gingivalis fimbrillin is one of the fibronectin-binding proteins.

Murakami, Y, Iwahashi, H, Yasuda, H, Umemoto, T, Namikawa, I, Kitano, S, ...

In this study, we demonstrate that Porphyromonas gingivalis fimbrillin, a major component of bacterial fimbriae, is one of the fibronectin-binding proteins and that fibronectin is a potent inhibitor...

CD14-mediated signal pathway of Porphyromonas gingivalis lipopolysaccharide in human gingival fibroblasts.

Watanabe, A, Takeshita, A, Kitano, S, Hanazawa, S

Lipopolysaccharide (LPS) induces expression of inflammatory cytokines in monocytes/macrophages via CD14, one of the LPS receptors, which is expressed predominantly in these cells. It has been...

Porphyromonas gingivalis lipopolysaccharide-stimulated bone resorption via CD14 is inhibited by broad-spectrum antibiotics.

Miyata, Y, Takeda, H, Kitano, S, Hanazawa, S

In the present study, we examined mechanisms of Porphyromonas gingivalis lipopolysaccharide (P-LPS)-stimulated bone resorption via CD14, one of the lipopolysaccharide (LPS) receptors, and also...

Porphyromonas gingivalis fimbria-stimulated bone resorption is inhibited through binding of the fimbriae to fibronectin.

Kawata, Y, Iwasaka, H, Kitano, S, Hanazawa, S

Our most recent study demonstrated that fibronectin is one of the Porphyromonas gingivalis fimbria-binding proteins. In this present study, we demonstrate with mouse embryonic calvarial cells that P....

Porphyromonas gingivalis fimbriae induce expression of the neutrophil chemotactic factor KC gene of mouse peritoneal macrophages: role of protein kinase C.

Hanazawa, S, Murakami, Y, Takeshita, A, Kitami, H, Ohta, K, Amano, S, ...

To account for infiltration of the periodontal tissues by neutrophils, the present study was undertaken to examine whether Porphyromonas gingivalis fimbriae, important structures involved in...

Bacteroides (Porphyromonas) gingivalis fimbriae activate mouse peritoneal macrophages and induce gene expression and production of interleukin-1.

Hanazawa, S, Murakami, Y, Hirose, K, Amano, S, Ohmori, Y, Higuchi, H, ...

The purpose of this study was to examine whether Bacteroides (Porphyromonas) gingivalis fimbriae, an important structure involved in attachment of the bacteria to periodontal tissues, activate...

Monoclonal antibody against a serotype antigen of Porphyromonas (Bacteroides) endodontalis and characteristics of the antigen.

Hanazawa, S, Sagiya, T, Amano, S, Nishikawa, H, Kitano, S

Recent studies have demonstrated the presence of three serotypes (O1K1, O1K2, and O1K-) of Porphyromonas (Bacteroides) endodontalis. In the present study, a hybridoma cell line producing monoclonal...

Bacteroides gingivalis fimbriae stimulate production of thymocyte-activating factor by human gingival fibroblasts.

Hanazawa, S, Hirose, K, Ohmori, Y, Amano, S, Kitano, S

In a previous report (Y. Ohmori, S. Hanazawa, S. Amano, T. Miyoshi, K. Hirose, and S. Kitano, infect. Immun. 55:947-954, 1987), we showed that human gingival fibroblasts spontaneously produce...

Spontaneous production of thymocyte-activating factor by human gingival fibroblasts and its autoregulatory effect on their proliferation.

Ohmori, Y, Hanazawa, S, Amano, S, Miyoshi, T, Hirose, K, Kitano, S

The purpose of this study was to examine whether human gingival fibroblasts produce a cytokine which modulates in immune and inflammatory responses including alterations in connective tissue...

Humoral antibody response against Bacteroides gingivalis-specific antigen recognized by monoclonal antibody in adult periodontal patients.

Miyoshi, T, Hanazawa, S, Hirose, K, Saitoh, K, Amano, S, Ohmori, Y, ...

An antigen recognized by monoclonal antibody specific for Bacteroides gingivalis was purified in the presence of 0.5% (wt/vol) beta-octyl-glucoside by immunoadsorbent column chromatography. The...

Production of monoclonal antibodies that recognize specific and cross-reactive antigens of Bacteroides gingivalis.

Hanazawa, S, Saitoh, K, Ohmori, Y, Nishihara, H, Fujiwara, S, Kitano, S

Four monoclonal antibodies directed against Bacteroides gingivalis were established by hybridoma technology. Their reactivity against B. gingivalis, Bacteroides intermedius, and Bacteroides...

Functional role of interleukin 1 in periodontal disease: induction of interleukin 1 production by Bacteroides gingivalis lipopolysaccharide in peritoneal macrophages from C3H/HeN and C3H/HeJ mice.

Hanazawa, S, Nakada, K, Ohmori, Y, Miyoshi, T, Amano, S, Kitano, S

Hot phenol-water-extracted lipopolysaccharide (LPS) from Bacteroides gingivalis 381 was purified by Sephadex G-100 chromatography with Tris buffer supplemented with sodium deoxycholate and EDTA...

Application of monoclonal antibodies to the detection of black-pigmented Bacteroides spp. in subgingival plaques by immunoslot blot assay.

Hanazawa, S, Tanaka, S, Kin, M, Amano, S, Nakada, K, Masuda, T, ...

The aim of the present study was to assess the application of monoclonal antibodies to the detection of black-pigmented Bacteroides spp. in subgingival plaques by immunoslot blot assay. Subgingival...

Monoclonal antibody against Porphyromonas (Bacteroides) endodontalis lipopolysaccharide and application of the antibody for direct identification of the species.

Hanazawa, S, Sagiya, T, Kitami, H, Ohta, K, Nishikawa, H, Kitano, S

The aim of the present study was to develop a monoclonal antibody that recognizes the shared antigen of Porphyromonas endodontalis so that we could use the antibody in direct identification and...

Expression of monocyte chemoattractant protein 1 (MCP-1) in adult periodontal disease: increased monocyte chemotactic activity in crevicular fluids and induction of MCP-1 expression in gingival tissues.

Hanazawa, S, Kawata, Y, Takeshita, A, Kumada, H, Okithu, M, Tanaka, S, ...

The present study shows that monocyte chemotactic activity in crevicular fluids increases with severity of the disease and that a monocyte chemoattractant, monocyte chemoattractant protein 1 (MCP-1),...

Nitric oxide mediates cytotoxicity and basic fibroblast growth factor release in cultured vascular smooth muscle cells. A possible mechanism of neovascularization in atherosclerotic plaques.

Fukuo, K, Inoue, T, Morimoto, S, Nakahashi, T, Yasuda, O, Kitano, S, ...

To define the pathophysiological role of nitric oxide (NO) released from vascular smooth muscle cells (VSMC), we examined whether NO released from VSMC induces cytotoxicity in VSMC themselves and...

Porphyromonas gingivalis fimbriae stimulate bone resorption in vitro.

Kawata, Y, Hanazawa, S, Amano, S, Murakami, Y, Matsumoto, T, Nishida, K, ...

Our previous study demonstrated that Porphyromonas gingivalis fimbriae induce the expression of interleukin-1, a potent bone-resorbing cytokine, in macrophages. This demonstration suggested to use...

Porphyromonas gingivalis fimbriae induce a 68-kilodalton phosphorylated protein in macrophages.

Murakami, Y, Hanazawa, S, Watanabe, A, Naganuma, K, Iwasaka, H, Kawakami, K, ...

The present study was performed to examine whether Porphyromonas gingivalis fimbriae induce specifically a protein kinase-mediated phosphorylated protein that is involved in the mechanism of signal...

Nucleotides. VI. Syntheses and spectral properties of some deazaadenylyl-deazaadenosines (dinucleoside monophosphates with unusual CD-spectrum) and closely related dinucleoside monophosphates.

Mizuno, Y, Kitano, S, Nomura, A

Nine dinucleoside phosphates containing 1-deaza-(1A) and 3-deazaadenosine (3A) were prepared. Hypochromicity and CD spectra of these dimers were determined. It was found that varying degrees of...

Quality of life after laparoscopy-assisted Billroth I gastrectomy.

Adachi, Y, Suematsu, T, Shiraishi, N, Katsuta, T, Morimoto, A, Kitano, S, ...

OBJECTIVE: To evaluate the quality of life of patients who had undergone laparoscopy-assisted Billroth I gastrectomy (LAG) for cure of cancer. SUMMARY BACKGROUND DATA: In 1994, the authors reported...

Increased expression of collagenase-3 (MMP-13) and MT1-MMP in oesophageal cancer is related to cancer aggressiveness

Etoh, T, Inoue, H, Yoshikawa, Y, Barnard, G, Kitano, S, Mori, M

BACKGROUND—Collagenase-3 (matrix metalloproteinase-13, MMP-13) is a recently identified human MMP with broad substrate specificity which can be activated by membrane type 1 (MT1) matrix...

Relation between retrobulbar circulation and progression of diabetic retinopathy

Dimitrova, G, Kato, S, Yamashita, H, Tamaki, Y, Nagahara, M, Fukushima, H, ...

Aims: To investigate retrobulbar circulatory parameters in type 2 diabetic patients with and without diabetic retinopathy (DR) progression.

The Fas and Fas ligand pathways in liver allograft tolerance

Pan, T L, Goto, S, Lin, Y C, Lord, R, Chiang, K C, Lai, C Y, ...

The Fas and Fas ligand (Fas/FasL) pathways may play a central role in cytotoxicity or immunoregulation in liver transplantation. Here, in an attempt to examine the role of Fas/FasL on drug-free...

Major hepatic resection may suppress the growth of tumours remaining in the residual liver

Yokoyama, H, Goto, S, Chen, C-L, Pan, T-L, Kawano, K, Kitano, S

Little is known as to how hepatectomy is associated with the growth of hepatic tumours, which may reside in the remaining liver after curative resection for hepatocellular carcinoma. Using an...