Ho, P. L., Poon, Winnie W. N., Loke, S. L., Leung, Marianne S. T., Chow, K. H., Wong, River C. W., ...
Objectives To conduct a territory-wide study of extended-spectrum β-lactamases (ESBLs) among community isolates of urinary Escherichia coli from women in Hong Kong. Methods Up to 50 consecutive...
Characterization of oligonucleotide transport into living cells.
Loke, S L, Stein, C A, Zhang, X H, Mori, K, Nakanishi, M, Subasinghe, C, ...
Addition of antisense oligonucleotides to cell cultures has been used to specifically inhibit gene expression. We have investigated the mechanism by which oligonucleotides enter living cells. These...
Epstein-Barr virus DNA in nasopharyngeal carcinomas from Chinese patients in Hong Kong.
Dickens, P, Srivastava, G, Loke, S L, Chan, C W, Liu, Y T
AIMS: To investigate the presence of Epstein-Barr virus (EBV) in cases of nasopharyngeal carcinoma (NPC) in Chinese patients living in Hong Kong. METHODS: Nasopharyngeal biopsy specimens, formalin...
AIMS--To determine the direction of differentiation of the mucin secreting components in a rare group of oesophageal tumours--oesophageal squamous cell carcinomas with prominent mucin secreting...
Improved silver technique for showing nucleolar organiser regions in paraffin wax sections.
Chiu, K Y, Loke, S L, Wong, K K
An improved technique for the demonstration of nucleolar organiser regions (NORs) was devised. It has the advantage that any non-specific background deposits which mimic the NOR dots formed during...
AIMS--To investigate the effects of fixation on the immunohistochemical demonstration of c-erbB-2 oncoprotein using paraffin wax and cryostat sections; to compare c-erbB-2 expression in...
Tao, Q, Srivastava, G, Loke, S L, Ho, F C
AIMS--To evaluate whether there is any correlation between the expression of Epstein-Barr virus (EBV) latent membrane protein (LMP) and oncoprotein bcl-2 in the lymph node biopsy specimens of a...
Tao, Q, Srivastava, G, Loke, S L, Chan, E Y, Ho, F C
AIMS--To develop and immunohistochemical staining method for cryostat and paraffin wax sections so that two different antigens in the same section of tissues could be detected by combining...
Localisation of CD10 to biliary canaliculi by immunoelectron microscopical examination.
Loke, S L, Leung, C Y, Chiu, K Y, Yau, W L, Cheung, K N, Ma, L
Common acute lymphoblastic leukaemia antigen (CALLA) was first characterised in lymphoid leukaemic cells. The antigen is present in different stages of lymphoid cell differentiation as well as in...
Human papillomavirus in oesophageal squamous cell carcinoma.
Loke, S L, Ma, L, Wong, M, Srivastava, G, Lo, I, Bird, C C
Thirty seven cases of oesophageal squamous cell carcinoma were studied by applying DNA slot blot analysis and in situ hybridisation using type specific probes for HPV 6, 11, 16 and 18. Cases of...
Characterization of oligonucleotide transport into living cells.
Loke, S L, Stein, C A, Zhang, X H, Mori, K, Nakanishi, M, Subasinghe, C, ...
Addition of antisense oligonucleotides to cell cultures has been used to specifically inhibit gene expression. We have investigated the mechanism by which oligonucleotides enter living cells. These...
Epstein-Barr virus DNA in nasopharyngeal carcinomas from Chinese patients in Hong Kong.
Dickens, P., Srivastava, G., Loke, S. L., Chan, C. W., Liu, Y. T.
AIMS: To investigate the presence of Epstein-Barr virus (EBV) in cases of nasopharyngeal carcinoma (NPC) in Chinese patients living in Hong Kong. METHODS: Nasopharyngeal biopsy specimens, formalin...
AIMS--To determine the direction of differentiation of the mucin secreting components in a rare group of oesophageal tumours--oesophageal squamous cell carcinomas with prominent mucin secreting...
Improved silver technique for showing nucleolar organiser regions in paraffin wax sections.
Chiu, K Y, Loke, S L, Wong, K K
An improved technique for the demonstration of nucleolar organiser regions (NORs) was devised. It has the advantage that any non-specific background deposits which mimic the NOR dots formed during...
AIMS--To investigate the effects of fixation on the immunohistochemical demonstration of c-erbB-2 oncoprotein using paraffin wax and cryostat sections; to compare c-erbB-2 expression in...
Tao, Q, Srivastava, G, Loke, S L, Ho, F C
AIMS--To evaluate whether there is any correlation between the expression of Epstein-Barr virus (EBV) latent membrane protein (LMP) and oncoprotein bcl-2 in the lymph node biopsy specimens of a...
Tao, Q, Srivastava, G, Loke, S L, Chan, E Y, Ho, F C
AIMS--To develop and immunohistochemical staining method for cryostat and paraffin wax sections so that two different antigens in the same section of tissues could be detected by combining...
Localisation of CD10 to biliary canaliculi by immunoelectron microscopical examination.
Loke, S L, Leung, C Y, Chiu, K Y, Yau, W L, Cheung, K N, Ma, L
Common acute lymphoblastic leukaemia antigen (CALLA) was first characterised in lymphoid leukaemic cells. The antigen is present in different stages of lymphoid cell differentiation as well as in...
Human papillomavirus in oesophageal squamous cell carcinoma.
Loke, S L, Ma, L, Wong, M, Srivastava, G, Lo, I, Bird, C C
Thirty seven cases of oesophageal squamous cell carcinoma were studied by applying DNA slot blot analysis and in situ hybridisation using type specific probes for HPV 6, 11, 16 and 18. Cases of...
c-myc protein in normal tissue. Effects of fixation on its apparent subcellular distribution.
Loke, S. L., Neckers, L. M., Schwab, G., Jaffe, E. S.
The c-myc protein is thought to be a DNA-associated nuclear protein. However, immunohistochemical studies on normal or tumor tissues have shown conflicting findings on its subcellular distribution....
Clonal Epstein-Barr virus genome in T-cell-rich lymphomas of B or probable B lineage.
Loke, S. L., Ho, F., Srivastava, G., Fu, K. H., Leung, B., Liang, R.
Seventeen nodal lymphomas (originally diagnosed as T-cell lymphomas based on histological features and immunohistochemical staining results) were studied for the presence of Epstein-Barr virus (EBV)...