Antibacterial single-bead screening (2003)
Lebreton, S., Newcombe, N., Bradley, M.
Triazine based antibiotics were prepared by the attachment of cyanuric chloride onto a Marshall-type safety catch linker, followed by successive aromatic nucleophilic substitutions, linker activation...
Lebreton, S., How, S. E., Buchholz, M., Yingyongnarongkul, B. E., Bradley, M.
Solid-phase synthesis is an ideal tool for reactions that require high concentrations and excess reagents and forcing chemical conditions. One such chemistry is that required for dendrimer...
Lebreton, S., Newcombe, N., Bradley, M.
Resins with loading up to 96 nmol/bead were prepared by solid.-phase dendrimerisation using a symmetrical 1-->3 C-branched isocyanate monomer.
Lebreton, S., Newcombe, N., Bradley, M.
High loading resins (up to 120 nmoles/bead) were preprared by solid-phase dendrimerisation using a novel 1-->3 C-branched isocyanate monomer.