Modeling network dynamics: the lac operon, a case study (2004)
Vilar, J. M. G., Guet, C. C., Leibler, S.
We use the lac operon in Escherichia coli as a prototype system to illustrate the current state, applicability, and limitations of modeling the dynamics of cellular networks. We integrate three...
Spiral Defects in Motility Assays: A Measure of Motor Protein Force (1995)
Bourdieu, L., Duke, T., Elowitz, M. B., Winkelmann, D. A., Leibler, S., Libchaber, A.
In a commonly used motility assay, cytoskeletal filaments are observed as they glide over a surface coated with motor proteins. Defects in the motion frequently interrupt the flow of filaments....
Vanishing tension of fluctuating membranes (1991)
The statistical behavior of fluctuating, flexible membranes or films can be governed by their (surface) tension or by their curvature energy, depending on imposed boundary conditions. We present here...
Vanishing tension of fluctuating membranes (1991)
The statistical behavior of fluctuating, flexible membranes or films can be governed by their (surface) tension or by their curvature energy, depending on imposed boundary conditions. We present here...
Vanishing tension of fluctuating membranes (1991)
The statistical behavior of fluctuating, flexible membranes or films can be governed by their (surface) tension or by their curvature energy, depending on imposed boundary conditions. We present here...
Stability of charged membranes (1990)
Bensimon, D., David, F., Leibler, S., Pumir, A.
The electrostatic contribution to the bending elastic modulus of charged phospholipid bilayers in an ionic solution is computed. It is found to be the same for conducting and non-conducting membranes...
Stretching and buckling of polymerized membranes: a Monte Carlo study (1990)
Guitter, E., Leibler, S., Maggs, A.C., David, F.
We study polymerized (elastic) membranes fluctuating under constrained boundary conditions. We show that the low-temperature, "flat" phase is not described by the classical theory of elasticity....
Stability of charged membranes (1990)
Bensimon, D., David, F., Leibler, S., Pumir, A.
The electrostatic contribution to the bending elastic modulus of charged phospholipid bilayers in an ionic solution is computed. It is found to be the same for conducting and non-conducting membranes...
Stretching and buckling of polymerized membranes: a Monte Carlo study (1990)
Guitter, E., Leibler, S., Maggs, A.C., David, F.
We study polymerized (elastic) membranes fluctuating under constrained boundary conditions. We show that the low-temperature, "flat" phase is not described by the classical theory of elasticity....
Stability of charged membranes (1990)
Bensimon, D., David, F., Leibler, S., Pumir, A.
The electrostatic contribution to the bending elastic modulus of charged phospholipid bilayers in an ionic solution is computed. It is found to be the same for conducting and non-conducting membranes...
Stretching and buckling of polymerized membranes: a Monte Carlo study (1990)
Guitter, E., Leibler, S., Maggs, A.C., David, F.
We study polymerized (elastic) membranes fluctuating under constrained boundary conditions. We show that the low-temperature, "flat" phase is not described by the classical theory of elasticity....
Thermodynamical behavior of polymerized membranes (1989)
Guitter, E., David, F., Leibler, S., Peliti, L.
We analyze by field theoretical methods the thermodynamical behavior of polymerized membranes, fluctuating without excluded volume interactions and in presence of either free or constrained boundary...
Thermodynamical behavior of polymerized membranes (1989)
Guitter, E., David, F., Leibler, S., Peliti, L.
We analyze by field theoretical methods the thermodynamical behavior of polymerized membranes, fluctuating without excluded volume interactions and in presence of either free or constrained boundary...
Thermodynamical behavior of polymerized membranes (1989)
Guitter, E., David, F., Leibler, S., Peliti, L.
We analyze by field theoretical methods the thermodynamical behavior of polymerized membranes, fluctuating without excluded volume interactions and in presence of either free or constrained boundary...
Ordered and curved meso-structures in membranes and amphiphilic films (1987)
Curvature-induced instabilities in membranes and amphiphilic films are investigated by introducing a general coupling between a shape variable (such as curvature) and «internal» degrees of freedom...
Ordered and curved meso-structures in membranes and amphiphilic films (1987)
Curvature-induced instabilities in membranes and amphiphilic films are investigated by introducing a general coupling between a shape variable (such as curvature) and «internal» degrees of freedom...
Ordered and curved meso-structures in membranes and amphiphilic films (1987)
Curvature-induced instabilities in membranes and amphiphilic films are investigated by introducing a general coupling between a shape variable (such as curvature) and «internal» degrees of freedom...
Curvature instability in membranes (1986)
A simple, thermodynamical model was proposed some time ago [1, 2] to describe the physical properties of various systems for which the curvature elastic energy plays an important role. The basis of...
Curvature instability in membranes (1986)
A simple, thermodynamical model was proposed some time ago [1, 2] to describe the physical properties of various systems for which the curvature elastic energy plays an important role. The basis of...
Curvature instability in membranes (1986)
A simple, thermodynamical model was proposed some time ago [1, 2] to describe the physical properties of various systems for which the curvature elastic energy plays an important role. The basis of...
A simple model describing 3He-4He mixtures near a wall (1984)
We describe the superfluid ordering taking place near a wall in 3 He-4He mixtures by means of a semi-infinite version of the Blume-Emery-Griffiths model. A renormalization group analysis of the...
A simple model describing 3He-4He mixtures near a wall (1984)
We describe the superfluid ordering taking place near a wall in 3 He-4He mixtures by means of a semi-infinite version of the Blume-Emery-Griffiths model. A renormalization group analysis of the...
A simple model describing 3He-4He mixtures near a wall (1984)
We describe the superfluid ordering taking place near a wall in 3 He-4He mixtures by means of a semi-infinite version of the Blume-Emery-Griffiths model. A renormalization group analysis of the...
A transfer matrix approach to the 3D wetting and pinning problems (1983)
Luck, J.M., Leibler, S., Derrida, B.
We consider the pinning of an interface on a 3D lattice by an edge potential (semi-infinite geometry). This situation models the wetting transition occurring in such physical systems as binary fluids...
Critical wetting : the domain of validity of mean field theory (1983)
Brézin, E., Halperin, B.I., Leibler, S.
Below the consolute point of a binary mixture, the presence of a wall which adsorbs preferentially one of the two liquids may induce a new transition, the wetting transition. Above the wetting...
A transfer matrix approach to the 3D wetting and pinning problems (1983)
Luck, J.M., Leibler, S., Derrida, B.
We consider the pinning of an interface on a 3D lattice by an edge potential (semi-infinite geometry). This situation models the wetting transition occurring in such physical systems as binary fluids...
Critical wetting : the domain of validity of mean field theory (1983)
Brézin, E., Halperin, B.I., Leibler, S.
Below the consolute point of a binary mixture, the presence of a wall which adsorbs preferentially one of the two liquids may induce a new transition, the wetting transition. Above the wetting...
A transfer matrix approach to the 3D wetting and pinning problems (1983)
Luck, J.M., Leibler, S., Derrida, B.
We consider the pinning of an interface on a 3D lattice by an edge potential (semi-infinite geometry). This situation models the wetting transition occurring in such physical systems as binary fluids...
Critical wetting : the domain of validity of mean field theory (1983)
Brézin, E., Halperin, B.I., Leibler, S.
Below the consolute point of a binary mixture, the presence of a wall which adsorbs preferentially one of the two liquids may induce a new transition, the wetting transition. Above the wetting...
Observation of an anomalous adsorption in a critical binary mixture (1982)
We have experimentally demonstrated the existence of a new critical anomaly in a binary mixture, due to the preferential adsorption of one of the components onto a solid wall.
Observation of an anomalous adsorption in a critical binary mixture (1982)
We have experimentally demonstrated the existence of a new critical anomaly in a binary mixture, due to the preferential adsorption of one of the components onto a solid wall.
Observation of an anomalous adsorption in a critical binary mixture (1982)
We have experimentally demonstrated the existence of a new critical anomaly in a binary mixture, due to the preferential adsorption of one of the components onto a solid wall.
Kinetics of self-assembling microtubules: an "inverse problem" in biochemistry.
Flyvbjerg, H, Jobs, E, Leibler, S
Experimental time series for a nonequilibrium reaction may in some cases contain sufficient data to determine a unique kinetic model for the reaction by a systematic mathematical analysis. As an...
Diffusion and formation of microtubule asters: physical processes versus biochemical regulation.
Dogterom, M, Maggs, A C, Leibler, S
Microtubule asters forming the mitotic spindle are assembled around two centrosomes through the process of dynamic instability in which microtubules alternate between growing and shrinking states. By...
Dynamic instability of microtubules as an efficient way to search in space.
During the formation of the mitotic spindle, dynamic microtubules search for chromosomes in the surrounding cytosol. The average time required to reach such "targets" is calculated within a simple...
Simulation of shape changes and adhesion phenomena in an elastic model of erythrocytes.
We present simulations of a model of a closed membrane that shares important features with erythrocytes: resistance to bending and shear, membrane asymmetry, and an osmotic pressure difference...
Geometrical aspects of the frustration in the cubic phases of lyotropic liquid crystals.
Anderson, D M, Gruner, S M, Leibler, S
Bicontinuous cubic phases, composed of bilayers arranged in the geometries of periodic minimal surfaces, are found in a variety of different lipid/water systems. It has been suggested recently that...
Response regulator output in bacterial chemotaxis.
Alon, U, Camarena, L, Surette, M G, Liu, Y, Leibler, S, ...
Chemotaxis responses in Escherichia coli are mediated by the phosphorylated response-regulator protein P-CheY. Biochemical and genetic studies have established the mechanisms by which the various...
Motor protein mechanics: a stochastic model with minimal mechanochemical coupling.
A stochastic model for the action of motor proteins such as kinesin is presented. The mechanical components of the enzyme are 1) two identical head domains that bind to discrete sites on a...
Kinetics of self-assembling microtubules: an "inverse problem" in biochemistry.
Flyvbjerg, H, Jobs, E, Leibler, S
Experimental time series for a nonequilibrium reaction may in some cases contain sufficient data to determine a unique kinetic model for the reaction by a systematic mathematical analysis. As an...
Diffusion and formation of microtubule asters: physical processes versus biochemical regulation.
Dogterom, M, Maggs, A C, Leibler, S
Microtubule asters forming the mitotic spindle are assembled around two centrosomes through the process of dynamic instability in which microtubules alternate between growing and shrinking states. By...
Dynamic instability of microtubules as an efficient way to search in space.
During the formation of the mitotic spindle, dynamic microtubules search for chromosomes in the surrounding cytosol. The average time required to reach such "targets" is calculated within a simple...
Simulation of shape changes and adhesion phenomena in an elastic model of erythrocytes.
We present simulations of a model of a closed membrane that shares important features with erythrocytes: resistance to bending and shear, membrane asymmetry, and an osmotic pressure difference...
Geometrical aspects of the frustration in the cubic phases of lyotropic liquid crystals.
Anderson, D M, Gruner, S M, Leibler, S
Bicontinuous cubic phases, composed of bilayers arranged in the geometries of periodic minimal surfaces, are found in a variety of different lipid/water systems. It has been suggested recently that...
Response regulator output in bacterial chemotaxis.
Alon, U, Camarena, L, Surette, M G, Liu, Y, Leibler, S, ...
Chemotaxis responses in Escherichia coli are mediated by the phosphorylated response-regulator protein P-CheY. Biochemical and genetic studies have established the mechanisms by which the various...
Motor protein mechanics: a stochastic model with minimal mechanochemical coupling.
A stochastic model for the action of motor proteins such as kinesin is presented. The mechanical components of the enzyme are 1) two identical head domains that bind to discrete sites on a...