S. Lonardi

Publication List Details

Period

2002 - 2007

Number

26

Co-Authors

Compression-based data mining of sequential data (2007)

Keogh, E, Lonardi, S, Ratanamahatana, C A, Wei, L, Lee, S H, Handley, J

The vast majority of data mining algorithms require the setting of many input parameters. The dangers of working with parameter-laden algorithms are twofold. First, incorrect settings may cause an...

Which benefit from adding gemcitabine to vinorelbine in elderly (>=70 years) women with metastatic breast cancer? Early interruption of a phase II study (2007)

Basso, U, Fratino, L, Brunello, A, Lumachi, F, De Salvo, GL, Lonardi, S, ...

Background: Since vinorelbine and gemcitabine are both active in breast cancer with moderate toxicity, in 2002 we started a phase II trial with a combination regimen in elderly patients. Patients and...

Finding biclusters by random projections (2006)

Lonardi, S, Szpankowski, W, Yang, Q F

Given a matrix X composed of symbols, a bicluster is a submatrix of X obtained by removing some of the rows and some of the columns of X in such a way that each row of what is left reads the same...

A bit level representation for time series data mining with shape based similarity (2006)

Bagnall, A, Ratanamahatana, C A, Keogh, E, Lonardi, S, Janacek, G

Clipping is the process of transforming a real valued series into a sequence of bits representing whether each data is above or below the average. In this paper, we argue that clipping is a useful...

OligoSpawn: a software tool for the design of overgo probes from large unigene datasets (2006)

Zheng, J, Svensson, J T, Madishetty, K, Close, T J, Jiang, T, Lonardi, S

Background: Expressed sequence tag (EST) datasets represent perhaps the largest collection of genetic information. ESTs can be exploited in a variety of biological experiments and analysis. Here we...

Evolution versus Intelligent Design: Comparing the Topology of Protein-Protein Interaction Networks to the Internet (2006)

Q. Yang, G. Siganos, M. Faloutsos, S. Lonardi

Recent research efforts have made available genome-wide, high-throughput protein-protein interaction (PPI) maps for several model organisms. This has enabled the systematic analysis of PPI networks,...

Evolution versus Intelligent Design: Comparing the Topology of Protein-Protein Interaction Networks to the Internet (2006)

Q. Yang, G. Siganos, M. Faloutsos, S. Lonardi

Recent research efforts have made available genome-wide, high-throughput protein-protein interaction (PPI) maps for several model organisms. This has enabled the systematic analysis of PPI networks,...

Data Min Knowl Disc DOI 10.1007/s10618-007-0064-z Experiencing SAX: a novel symbolic representation of time series (2006)

Jessica Lin, Eamonn Keogh, Li Wei, Stefano Lonardi, J. Lin (b, E. Keogh, ...

Abstract Many high level representations of time series have been proposed for data mining, including Fourier transforms, wavelets, eigenwaves, piecewise polynomial models, etc. Many researchers have...

Evolution versus Intelligent Design: Comparing the Topology of Protein-Protein Interaction Networks to the Internet (2006)

Q. Yang, G. Siganos, M. Faloutsos, S. Lonardi

Recent research efforts have made available genome-wide, high-throughput protein-protein interaction (PPI) maps for several model organisms. This has enabled the systematic analysis of PPI networks,...

Which benefit from adding gemcitabine to vinorelbine in elderly (>=70 years) women with metastatic breast cancer? Early interruption of a phase II study (2006)

Basso, U., Fratino, L., Brunello, A., Lumachi, F., De Salvo, G. L., Lonardi, S., ...

Background: Since vinorelbine and gemcitabine are both active in breast cancer with moderate toxicity, in 2002 we started a phase II trial with a combination regimen in elderly patients. Patients and...

Which benefit from adding gemcitabine to vinorelbine in elderly (>=70 years) women with metastatic breast cancer? Early interruption of a phase II study (2006)

Basso, U., Fratino, L., Brunello, A., Lumachi, F., De Salvo, G. L., Lonardi, S., ...

Background: Since vinorelbine and gemcitabine are both active in breast cancer with moderate toxicity, in 2002 we started a phase II trial with a combination regimen in elderly patients. Patients and...

Assignment of orthologous genes via genome rearrangement (2005)

Chen, X, Zheng, J, Fu, Z, Nan, P, Zhong, Y, Lonardi, S, ...

The assignment of orthologous genes between a pair of genomes is a fundamental and challenging problem in comparative genomics. Existing methods that assign orthologs based on the similarity between...

A novel bit level time series representation with implication of similarity search and clustering (2005)

Ratanamahatana, C, Keogh, E, Bagnal, A J, Lonardi, S

Because time series are a ubiquitous and increasingly prevalent type of data, there has been much research effort devoted to time series data mining recently. As with all data mining problems, the...

Integrating lite-weight but ubiquitous data mining into GUI operating systems (2005)

Wei, L, Keogh, E, Xi, X P, Lonardi, S

Most visualization tools introduced in the literature are specialized for a particular task. In this work, we introduce a novel framework which allows visualization to take place in the background of...

Computing the assignment of orthologous genes via genome rearrangement (2005)

X. Chen, J. Zheng, Z. Fu, P. Nan, Y. Zhong, S. Lonardi, ...

The assignment of orthologous genes between a pair of genomes is a fundamental and challenging problem in comparative genomics. Existing methods that assign orthologs based on the similarity between...

Data Min Knowl Disc DOI 10.1007/s10618-006-0049-3 Compression-based data mining of sequential data (2005)

Eamonn Keogh, Stefano Lonardi Chotirat, Ann Ratanamahatana, Lee John H, S. Lonardi, ...

Abstract The vast majority of data mining algorithms require the setting of many input parameters. The dangers of working with parameter-laden algorithms are twofold. First, incorrect settings may...

A phase I-II study of weekly oxaliplatin, 5-fluorouracil continuous infusion and preoperative radiotherapy in locally advanced rectal cancer (2005)

Aschele, C., Friso, M. L., Pucciarelli, S., Lonardi, S., Sartor, L., Fabris, G., ...

Background: Oxaliplatin (OXA) significantly enhanced the antitumour activity of 5-fluorouracil (FUra) in patients with advanced colorectal cancer and displayed radiosensitising properties in...

A phase I-II study of weekly oxaliplatin, 5-fluorouracil continuous infusion and preoperative radiotherapy in locally advanced rectal cancer (2005)

Aschele, C., Friso, M. L., Pucciarelli, S., Lonardi, S., Sartor, L., Fabris, G., ...

Background: Oxaliplatin (OXA) significantly enhanced the antitumour activity of 5-fluorouracil (FUra) in patients with advanced colorectal cancer and displayed radiosensitising properties in...

On average sequence complexity (2004)

Janson, S, Lonardi, S, Szpankowski, W

In this paper we study the average behavior of the number of distinct substrings in a text of size n over an alphabet of cardinality k. This quantity is called the complexity index and it captures...

Augmenting LZ-77 with authentication and integrity assurance capabilities (2004)

Atallah, M J, Lonardi, S

The formidable dissemination capability allowed by the current network technology makes it increasingly important to devise new methods to ensure authenticity and integrity. Nowadays it is common...

Verbumculus and the discovery of unusual words (2004)

Apostolico, A, Gong, F C, Lonardi, S

Measures relating word frequencies and expectations have been constantly of interest in Bioinformatics studies. With sequence data becoming massively available, exhaustive enumeration of such...

Carboplatin and teniposide as third-line chemotherapy in patients with recurrent oligodendroglioma or oligoastrocytoma: a phase II study (2003)

Brandes, A. A., Basso, U., Vastola, F., Tosoni, A., Pasetto, L. M., Jirillo, A., ...

Background: This study was a phase II study of third-line chemotherapy with carboplatin plus teniposide in patients with recurrent oligodendroglioma. Patients and methods: Patients with...

Thymidylate synthase protein expression in colorectal cancer metastases predicts for clinical outcome to leucovorin-modulated bolus or infusional 5-fluorouracil but not methotrexate-modulated bolus 5-fluorouracil (2002)

Aschele, C., Debernardis, D., Bandelloni, R., Cascinu, S., Catalano, V., Giordani, P., ...

Background: Different 5-fluorouracil (5-FU) schedules and/or biochemical modulators may result in different mechanisms of cytotoxicity, potentially affecting the correlation between thymidylate...

Gefitinib in patients with progressive high-grade gliomas: a multicentre phase II study by Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO)

Franceschi, E, Cavallo, G, Lonardi, S, Magrini, E, Tosoni, A, Grosso, D, ...

To investigate the role of gefitinib in patients with high-grade gliomas (HGGs), a phase II trial (1839IL/0116) was conducted in patients with disease recurrence following surgery plus radiotherapy...