Prostaglandin 15 (R) 15-methyl-E2 Methyl Ester for Suppression of Gastric Acidity in Gravida at Term
Amy, J. J., Jackson, D. M., Ganesan, P. Adaikan, Karim, S. M. M.
During the second hour after giving 100 μg of orally administered prostaglandin 15 (R) 15-methyl-E2 methyl ester in the pregnant patient at term a noticeable reduction in basal gastric acid...
Effect of Orally Administered Prostaglandin E2 and its 15-Methyl Analogues on Gastric Secretion
Karim, S. M. M., Carter, D. C., Bhana, D., Ganesan, P. Adaikan
The effect of orally administered prostaglandin E2 and its synthetic 15-methyl analogues on gastric secretion in man was studied. The parent E2 compound did not inhibit basal secretion, whereas both...
Use of Prostaglandin E2 for Therapeutic Abortion
Karim, S. M. M., Filshie, G. M.
Termination of pregnancy was attempted with intravenous infusion of prostaglandin E2 (5 μg./minute) in 52 consecutive cases. Abortion was successful in 50 of these and complete in 43. There were no...
Use of Prostaglandin E2 in the Management of Missed Abortion, Missed Labour, and Hydatidiform Mole
Treatment of six cases of missed abortion and one case of hydatidiform mole with intravenous infusion of prostaglandin E2 resulted in complete abortion in all cases. Of 15 patients with missed...
Prostaglandin 15 (R) 15-methyl-E2 Methyl Ester for Suppression of Gastric Acidity in Gravida at Term
Amy, J. J., Jackson, D. M., Ganesan, P. Adaikan, Karim, S. M. M.
During the second hour after giving 100 μg of orally administered prostaglandin 15 (R) 15-methyl-E2 methyl ester in the pregnant patient at term a noticeable reduction in basal gastric acid...
Effect of Orally Administered Prostaglandin E2 and its 15-Methyl Analogues on Gastric Secretion
Karim, S. M. M., Carter, D. C., Bhana, D., Ganesan, P. Adaikan
The effect of orally administered prostaglandin E2 and its synthetic 15-methyl analogues on gastric secretion in man was studied. The parent E2 compound did not inhibit basal secretion, whereas both...
Use of Prostaglandin E2 for Therapeutic Abortion
Karim, S. M. M., Filshie, G. M.
Termination of pregnancy was attempted with intravenous infusion of prostaglandin E2 (5 μg./minute) in 52 consecutive cases. Abortion was successful in 50 of these and complete in 43. There were no...
Use of Prostaglandin E2 in the Management of Missed Abortion, Missed Labour, and Hydatidiform Mole
Treatment of six cases of missed abortion and one case of hydatidiform mole with intravenous infusion of prostaglandin E2 resulted in complete abortion in all cases. Of 15 patients with missed...
Oral Administration of Prostaglandins for the Induction of Labour
Karim, S. M. M., Sharma, S. D.
Prostaglandins E2 and F2α administered by mouth were used to induce labour in 100 patients between 35 and 44 weeks of gestation. The usual effective dose of prostaglandin E2 was 0·5 and of F2α 5...
Appearance of Prostaglandin F2α in Human Blood during Labour*
Blood samples from over 70 pregnant women have been examined for the presence of four prostaglandins. Samples obtained from women not in labour at different gestation periods and at term contained no...
Response of Pregnant Human Uterus to Prostaglandin-F2α-induction of Labour*
Karim, S. M. M., Trussell, R. R., Patel, R. C., Hillier, K.
Labour was successfully induced in 10 women at or near term with prostaglandin F2α infusion. In no case was there an increase in the resting tone of the myometrium, and complete relaxation between...
Antagonism of some smooth muscle actions of prostaglandins by polyphloretin phosphate
Eakins, K. E., Karim, S. M. M., Miller, J. D.
1. The antagonism of the smooth muscle stimulating actions of PGF2a and PGE2 by polyphloretin phosphate (PPP) was studied on several isolated smooth muscle preparations and on the blood pressure of...
The mechanism of the depressor action of noradrenaline in the cat
In cats anaesthetized with pentobarbitone sodium or chloralose and injected with phenoxybenzamine or phentolamine, administration of (—)-noradrenaline (5 to 20 μg) produced a fall of blood...