S. Minucci

Epigenetic therapies for acute myeloid leukemias : pre-clinical validation and study of molecular mechanisms (2008)

MINUCCI, SAVERIO, SONCINI, MATIAS CRISTOBAL, S. Minucci

Epigenetic therapies for acute myeloid leukemias : pre-clinical validation and study of molecular mechanisms / Matias Cristobal Soncini ; S. Minucci. - Milano, 2008. ((19. ciclo . - A.a. 2006/2007. -...

PML4 induces differentiation by Myc destabilization (2007)

Buschbeck, M., Uribesalgo, I., Ledl, A., Gutierrez, A., Minucci, S., Müller, S., ...

The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells (2007)

BRACKEN, AP, KLEINE-KOHLBRECHER, D, DIETRICH, N, PASINI, D, GARGIULO, G, Beekman, Chantal, ...

PML4 induces differentiation by Myc destabilization (2006)

Buschbeck, M., Uribesalgo, I., Ledl, A., Gutierrez, A., Minucci, S., Müller, S., ...

Alleati di Hitler: le regie forze armate, il regime fascista, e la guerra del 1940-1943 (2002)

Knox, MacGregor, Minucci, S.

Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells. (2002)

Göttlicher, M., Minucci, S., Zhu, P., Krämer, O.H., Schimpf, A., Giavara, S., ...

The EMBO Journal, 20(2001) S.6969-78

The teratogen valproic acid defines a novel class of histone deacetylase inhibitors inducing differentiation of embryonic, transformed and tumorigenic cells. (2002)

Göttlicher, M., Minucci, S., Zhu, P., Krämer, O.H., Schimpf, A., Giavara, S., ...

43.Frühjahrstagung der Deutschen Gesellschaft für experimentelle und klinische Pharmakologie und Toxikologie (DGPT), Mainz, 12.-14.März 2002

Valproic acid defines a novel class of histone deacetylase inhibitors inducing differentiation of transformed and tumorigenic cells. (2002)

Göttlicher, M., Minucci, S., Zhu, P., Krämer, O.H., Schimpf, A., Giavara, S., ...

93rd Annual Meeting of the American Association for Cancer Research, San Francisco, Calif., April 6-10, 2002

Retinoid X receptor-selective ligands produce malformations in Xenopus embryos.

Minucci, S, Saint-Jeannet, J P, Toyama, R, Scita, G, DeLuca, L M, Tiara, M, ...

Retinoids exert pleiotropic effects on the development of vertebrates through the action of retinoic acid receptors (RAR) and retinoid X receptors (RXR). We have investigated the effect of synthetic...

Proteolytic activity of the purified hormone-binding subunit in the estrogen receptor.

Molinari, A M, Abbondanza, C, Armetta, I, Medici, N, Minucci, S, Moncharmont, B, ...

The hormone-binding subunit of the calf uterus estradiol receptor was purified as a hormone-free molecule. Immunoaffinity chromatography with a specific monoclonal antibody was used as the final...

Retinoid X receptor (RXR) within the RXR-retinoic acid receptor heterodimer binds its ligand and enhances retinoid-dependent gene expression.

Minucci, S, Leid, M, Toyama, R, Saint-Jeannet, J P, Peterson, V J, Horn, V, ...

Retinoic acid receptor (RAR) and retinoid X receptor (RXR) form heterodimers and regulate retinoid-mediated gene expression. We studied binding of RXR- and RAR-selective ligands to the RXR-RAR...

Retinoid-induced chromatin structure alterations in the retinoic acid receptor beta2 promoter.

Bhattacharyya, N, Dey, A, Minucci, S, Zimmer, A, John, S, Hager, G, ...

Transcription of the retinoic acid receptor beta2 (RARbeta2) gene is induced by retinoic acid (RA) in mouse P19 embryonal carcinoma (EC) cells. Here we studied RA-induced chromatin structure...

Dominant negative retinoid X receptor beta inhibits retinoic acid-responsive gene regulation in embryonal carcinoma cells.

Minucci, S, Zand, D J, Dey, A, Marks, M S, Nagata, T, Grippo, J F, ...

Retinoid X receptors (RXRs) heterodimerize with multiple nuclear hormone receptors and are thought to exert pleiotropic functions. To address the role of RXRs in retinoic acid- (RA) mediated gene...

Retinoic acid-mediated down-regulation of Oct3/4 coincides with the loss of promoter occupancy in vivo.

Minucci, S, Botquin, V, Yeom, Y I, Dey, A, Sylvester, I, Zand, D J, ...

Oct3/4, a hallmark of the earliest stages of embryogenesis, is expressed in undifferentiated embryonal carcinoma (EC) and embryonic stem (ES) cells. Oct3/4 gene expression is dependent on the...

Ligand-dependent occupancy of the retinoic acid receptor beta 2 promoter in vivo.

Dey, A, Minucci, S, Ozato, K

Retinoic acid (RA) activates transcription of the RA receptor beta 2 (RAR beta 2) gene in embryonal carcinoma (EC) cells. This activation involves binding of the RAR/retinoid X receptor (RAR/RXR)...

The orbital glands of the chelonians Pseudemys scripta and Testudo graeca: comparative histological, histochemical and ultrastructural investigations.

Chieffi Baccari, G, DiMatteo, L, Minucci, S

The orbital glands of the chelonians Pseudemys scripta and Testudo graeca were investigated at the histological, histochemical and ultrastructural levels. Four acinar cell types were seen in the...

The orbital glands of the terrapin Pseudemys scripta in response to osmotic stress: a light and electron microscope study.

Baccari, G C, Minucci, S, Di Matteo, L

The histochemical and ultrastructural features of both orbital glands--the anterior lacrimal and harderian glands--were compared in the terrapin Pseudemys scripta following adaptation either to...

Number of mast cells in the harderian gland of the green frog, Rana esculenta: the annual cycle and its relation to environmental and hormonal factors.

Chieffi Baccari, G, Minucci, S, Marmorino, C, Vitiello Izzo, I

The Harderian gland of the green frog contains mast cells. Their number shows annual variations, being more numerous in the winter months. The increase of mast cell number (MCN) is matched by a...

Retinoid X receptor-selective ligands produce malformations in Xenopus embryos.

Minucci, S, Saint-Jeannet, J P, Toyama, R, Scita, G, DeLuca, L M, Tiara, M, ...

Retinoids exert pleiotropic effects on the development of vertebrates through the action of retinoic acid receptors (RAR) and retinoid X receptors (RXR). We have investigated the effect of synthetic...

Proteolytic activity of the purified hormone-binding subunit in the estrogen receptor.

Molinari, A M, Abbondanza, C, Armetta, I, Medici, N, Minucci, S, Moncharmont, B, ...

The hormone-binding subunit of the calf uterus estradiol receptor was purified as a hormone-free molecule. Immunoaffinity chromatography with a specific monoclonal antibody was used as the final...

Retinoid X receptor (RXR) within the RXR-retinoic acid receptor heterodimer binds its ligand and enhances retinoid-dependent gene expression.

Minucci, S, Leid, M, Toyama, R, Saint-Jeannet, J P, Peterson, V J, Horn, V, ...

Retinoic acid receptor (RAR) and retinoid X receptor (RXR) form heterodimers and regulate retinoid-mediated gene expression. We studied binding of RXR- and RAR-selective ligands to the RXR-RAR...

Retinoid-induced chromatin structure alterations in the retinoic acid receptor beta2 promoter.

Bhattacharyya, N, Dey, A, Minucci, S, Zimmer, A, John, S, Hager, G, ...

Transcription of the retinoic acid receptor beta2 (RARbeta2) gene is induced by retinoic acid (RA) in mouse P19 embryonal carcinoma (EC) cells. Here we studied RA-induced chromatin structure...

Dominant negative retinoid X receptor beta inhibits retinoic acid-responsive gene regulation in embryonal carcinoma cells.

Minucci, S, Zand, D J, Dey, A, Marks, M S, Nagata, T, Grippo, J F, ...

Retinoid X receptors (RXRs) heterodimerize with multiple nuclear hormone receptors and are thought to exert pleiotropic functions. To address the role of RXRs in retinoic acid- (RA) mediated gene...

Ligand-dependent occupancy of the retinoic acid receptor beta 2 promoter in vivo.

Dey, A, Minucci, S, Ozato, K

Retinoic acid (RA) activates transcription of the RA receptor beta 2 (RAR beta 2) gene in embryonal carcinoma (EC) cells. This activation involves binding of the RAR/retinoid X receptor (RAR/RXR)...

Retinoic acid-mediated down-regulation of Oct3/4 coincides with the loss of promoter occupancy in vivo.

Minucci, S, Botquin, V, Yeom, Y I, Dey, A, Sylvester, I, Zand, D J, ...

Oct3/4, a hallmark of the earliest stages of embryogenesis, is expressed in undifferentiated embryonal carcinoma (EC) and embryonic stem (ES) cells. Oct3/4 gene expression is dependent on the...

The orbital glands of the chelonians Pseudemys scripta and Testudo graeca: comparative histological, histochemical and ultrastructural investigations.

Chieffi Baccari, G, DiMatteo, L, Minucci, S

The orbital glands of the chelonians Pseudemys scripta and Testudo graeca were investigated at the histological, histochemical and ultrastructural levels. Four acinar cell types were seen in the...

The orbital glands of the terrapin Pseudemys scripta in response to osmotic stress: a light and electron microscope study.

Baccari, G C, Minucci, S, Di Matteo, L

The histochemical and ultrastructural features of both orbital glands--the anterior lacrimal and harderian glands--were compared in the terrapin Pseudemys scripta following adaptation either to...

Number of mast cells in the harderian gland of the green frog, Rana esculenta: the annual cycle and its relation to environmental and hormonal factors.

Chieffi Baccari, G, Minucci, S, Marmorino, C, Vitiello Izzo, I

The Harderian gland of the green frog contains mast cells. Their number shows annual variations, being more numerous in the winter months. The increase of mast cell number (MCN) is matched by a...