Karayiannis, P, O'Rourke, S, Watts, R, Waters, J, Hill, V, Carman, W F, ...
We have generated a number of recombinant vaccinia viruses which expressed the hepatitis A virus (HAV) structural polypeptides VP1, VP2, VP3, and VP4, either alone or in combination. The relevant...
Inactivation of contraceptive steroid hormones by human intestinal clostridia.
Bokkenheuser, V D, Winter, J, Cohen, B I, O'Rourke, S, Mosbach, E H
Steroid hormones reduced in ring-A are devoid of hormonal activity. In metabolic experiments we found that human fecal flora reduced the delta 4-3-keto structure of natural progestins to 3...
Isolation and characterization of fecal bacteria capable of 16 alpha-dehydroxylating corticoids.
Bokkenheuser, V D, Winter, J, O'Rourke, S, Ritchie, A E
For more than a decade it has been known that the fecal flora of humans and rats includes organisms capable of 16 alpha-dehydroxylating corticoids, but their identity has remained unknown. To isolate...
Karayiannis, P, O'Rourke, S, Watts, R, Waters, J, Hill, V, Carman, W F, ...
We have generated a number of recombinant vaccinia viruses which expressed the hepatitis A virus (HAV) structural polypeptides VP1, VP2, VP3, and VP4, either alone or in combination. The relevant...
Inactivation of contraceptive steroid hormones by human intestinal clostridia.
Bokkenheuser, V D, Winter, J, Cohen, B I, O'Rourke, S, Mosbach, E H
Steroid hormones reduced in ring-A are devoid of hormonal activity. In metabolic experiments we found that human fecal flora reduced the delta 4-3-keto structure of natural progestins to 3...
Isolation and characterization of fecal bacteria capable of 16 alpha-dehydroxylating corticoids.
Bokkenheuser, V D, Winter, J, O'Rourke, S, Ritchie, A E
For more than a decade it has been known that the fecal flora of humans and rats includes organisms capable of 16 alpha-dehydroxylating corticoids, but their identity has remained unknown. To isolate...
Waters, J A, O'Rourke, S, Schlict, H J, Thomas, H C
Cytotoxic T cells have been identified in the peripheral blood of patients with acute hepatitis B virus infections for a short period after clinical presentation. However, in patients in whom the...
Evaluation of a stroke family care worker: results of a randomised controlled trial.
Dennis, M., O'Rourke, S., Slattery, J., Staniforth, T., Warlow, C.
OBJECTIVE: To examine the effect of contact with a stroke family care worker on the physical, social, and psychological status of stroke patients and their carers. DESIGN: Randomised controlled trial...
Emotional outcomes after stroke: factors associated with poor outcome
Dennis, M., O'Rourke, S., Lewis, S., Sharpe, M., Warlow, C.
OBJECTIVES—The impact of stroke on the emotional outcome of patients is large. The aim was to describe the emotional outcomes among a cohort of patients which was of sufficient size to provide a...
Depression and its relation to lesion location after stroke
MacHale, S., O'Rourke, S., Wardlaw, J., Dennis, M.
The study of discrete organic cerebral lesions resulting in clearly definable psychiatric disorders may provide an understanding of the underlying patho-physiological basis of these disorders....
Odontoid lateral mass asymmetry: do we over-investigate?
Harty, J, Lenehan, B, O'Rourke, S
Objectives: This study aimed to evaluate the necessity for further radiological investigation in patients with suspected traumatic rotatory subluxation of the atlanto-axial complex on plain...