Based on theories of laminate anisotropic elasticity and interlaminar fracture, the complete solution structure associated with a composite delamination is determined. Fracture mechanics parameters...
The fundamental mechanics of delamination in fiber composite laminates is studied. Mathematical formulation of the problem is based on laminate anisotropic elasticity theory and interlaminar fracture...
Single-nucleotide polymorphisms in selected cytokine genes and risk of adult glioma (2007)
Brenner, A.V., Butler, M.A., Wang, S.S., Ruder, A.M., Rothman, N., Schulte, P.A., ...
A role of immunological factors in glioma etiology is suggested by reports of an inverse relationship with history of allergy or autoimmune disease. To test whether single-nucleotide polymorphisms...
Modelling carbon dynamics of boreal forest ecosystems using the Canadian Land Surface Scheme (2002)
Wang, ShuSen, Grant, R.F., Verseghy, D.L., Black, T.A., Wang, S.S.
Smith, Alvin, Wang, S. S., Kuo, A. Y.
Volume I of this report (1) presents the findings of a study conducted to develop a low-density polyurethane foam system that is deployable within 5 seconds, and (2) documents a study of foam/fabric...
Fracture of Graphite Fiber Reinforced Composites. (1999)
Mandell,J. F., Wang,S. S., McGarry,F. J.
The fracture of thin prenotched graphite/ epoxy laminates has been studied analytically and experimentally. Analytical solutions were obtained for the three- dimensional stress field at the tip of...
Analysis of Cracks in Nonlinear Fiber Composite Materials, (1998)
The effect of effective material nonlinear properties of fiber composites on crack behavior is studied. Three-dimensional nonlinear constitutive equations are established, based on both complementary...
Developments of advanced fiber-composite laminates as viable structural components have introduced new complexities in design. Among these concerns is the load-bearing capacity of these structures...
Micromechanics Analysis of Fiber Toughening in Ceramic-Matrix Composites. (1998)
Finite element analysis combined with elasticity results governing fiber pullout is used to investigate toughening of undirectional fiber-reinforced ceramic matrix composites. The most important...
Doong, S. H., Faoro, J. E., Socie, D. F., Wang, S. S.
This paper presents the development of a test system and associated experimental procedure for evaluating in-plane biaxial compressive deformation and failure of fiber composite laminates. A...
Fiber-composite laminate shell structures have been used increasingly in advanced engineering structures, such as aircraft fuselages, deep submersibles and surface ships. Among various critical...
Chen, A. W., Miyase, A., Wang, S. S., Geil, P. H.
This, the first of a series of papers on the properties of a thermoplastic polyamide matrix (J1, du Pont, poly (bis 4-4' dicyclohexylmethane) n-dodecane-diamide)/graphite fiber (AS4, Hercules)...
Creep and Physical Aging in a Polyamideimide-Carbon Fiber Composite. (1998)
Nichols, M. E., Wang, S. S., Geil, P. H.
The creep properties of an amorphous thermoplastic polyamideimide and it's continuous carbon fiber composite have been investigated. Creep behavior in the viscoelastic (low stress) and viscoplastic...
Miyase, A., Wang, S. S., Chen, A., Geil, P. H.
Structural characterization of the AS4-graphite/J1-polymer composite were conducted, using Differential Scanning Calorimetry (DSC) and Wide-Angel X-Ray Diffraction (WAXD) analysis. The DSC results...
Elevated-Temperature Crack Growth and Fracture in Thermoplastic Polymers. (1998)
Elevated-temperature crack growth and fracture behavior in a thermoplastic polymer are investigated. Owing to the significantly nonlinear constitutive properties, a nonlinear fracture mechanics...
Wang, S. S., Blondet, J., Miyase, A., Su, K. B.
A study on the interlaminar fatigue crack growth behavior in a thermoplastic matrix composite at both room elevated temperatures is presented. Experiments are conducted on an AS4-graphite...
Miyase, A., Chen, A. W.-L., Geil, P. H., Wang, S. S.
This is the second in a series of papers on the anelastic deformation behavior of a thermoplastic polymer-matrix/graphite-fiber composite. In the previous paper we reported the structural...
Creep Buckling of Thermoplastic-Matrix Fiber Composites under Biaxial Loading. (1998)
An analytical study has been conducted to investigate the elevated- temperature creep buckling behavior of thermoplastic-matrix composite laminates subjected to multiaxial loading. Anisotropic...
A study of transverse crack growth and fracture behavior in a thermoplastic-matrix fiber composite at bath room and elevated temperatures is conducted. Owing to the significant ductility of...
High-temperature, thermoelastic constitutive properties of a randomly oriented whisker-reinforced ceramic composite under a small temperature change are studied theoretically and numerically. Based...
Silicon carbide (SiC) fibers and whiskers are recently utilized as important reinforcements for advanced high-temperature metal-matrix and ceramic composites owing to their outstanding mechanical...
Edge Delamination In Angle-Ply Composite Laminates. Part 5. (1998)
Edge delamination has caused severe concern in the design and analysis of advanced composite materials and structures. Due to its complex nature, very limited knowledge for the problem is currently...
Interlaminar Crack Growth in Fiber Reinforced Composites During Fatigue. Part 3. (1998)
Interlaminar crack growth behavior in fiber-reinforced composites subjected to fatigue loading was investigated experimentally and theoretically. In the experimental phase of the study, interlaminar...
An analytical method is developed for cracks emanating from a circular hole in an off-axis unidirectional fiber-reinforced composite. The method is formulated by using conservation laws of elasticity...
Analysis of Interface Cracks in Adhesively Bonded Lap Shear Joints. Part 4. (1998)
The conservation laws of elasticity for nonhomogeneous materials developed under this grant are used to study the crack behavior in adhesively bonded lap shear joints. These laws and the fundamental...
Boundary Layer Thermal Stresses in Angle-Ply Composite Laminates. Part 1. (1998)
Thermal boundary-layer stresses (near free edges) and displacements are determined by a unique method developed under this grant. This method consists of an eigenfunction expansion technique and the...
Boundary-Layer Effects in Composite Laminates: Free-Edge Stress Singularities. Part 6. (1998)
A rigorous mathematical model has been obtained for the boundary-layer free-edge stress singularity in angleplied and crossplied fiber composite laminates. The solution was obtained using the...
Surface Crack Growth in Fiber Composites. (1998)
Im, J., Mandell, J. F., Wang, S. S., McGarry, F. J.
The results of an experimental study of damage extension and failure in glass and graphite/epoxy laminates containing partially through-thickness surface cracks are presented. The laminates studied...
In this project, research efforts have been made to address some of the most critical and complex issues on high-temperature damage, degradation and failure of advanced composites. For the...
Elevated Temperature Transverse Creep of FP/Al-2Li Metal-Matrix Composite. (1998)
Balis, C. D., Curran, D. R., Wang, S. S.
A study on the elevated temperature transverse deformation of the fp-fiber reinforced aluminum alloy was done. the first tests were monotonic transverse tension performed at room temperature and at...
A compressive study on the cyclic compressive fatigue damage has been conducted on the fp-fiber reinforced aluminum alloy. first, the compressive fatigue life of the fp/a1-2li mmc was determined, and...
Jones, C., Kiely, C. J., Wang, S. S.
OF AN SCS6/TI-6AL-4V METAL MATRIX COMPOSITE UPON EXPOSURE TO VARYING HEAT TREATMENTS HAVE BEEN STUDIED. IT IS THOUGHT THAT CHANGES SUCH AS THE FORMATION OF SMALL TIC PARTICLES AT ONE INTERFACE, AND...
Jones, C., Kiely, C. J., Wang, S. S.
The changes in the chemistry and morphology within the interphases region of an scs6/ti-6al-4v metal matrix composite upon exposing the samples to varying heat treatments have been studied using...
Cai, G.G., Bestion, N., Wang, S.S., Shen, W.X., Delard, R., Volpiliere, J., ...
The dose responses for LiF:Mg,Ti (TLD-100) and LiF:Mg,Cu,P (GR-200A) have been examined at the photon energies of 30, 104 and 1250 keV. A GCA programme has been used for the deconvolution of the glow...
Thermal Neutron and Gamma Responses of 6LiF:Mg,Cu,P and 7LiF:Mg,Cu,P TL Films (1991)
Cai, G.G., Wang, S.S., Wu, F., Zha, Z.Y., Zhou, K.Q., Li, L.P.
Thermal neutron and gamma responses of 6LiF/7LiF:Mg,Cu,P TL films have been investigated and the experimental procedure is described in detail. The films consist of a layer of polyamide as substrate,...
Wang, S.S., Cai, G.G., Zhou, K.Q., Zhou, R.X.
The newly developed 6LiF (Mg,Cu,P) and 7LiF (Mg,Cu,P) TL chips have been investigated for their relative TL sensitivity, glow curve structure, photon energy dependence, gamma ray and neutron dose...
Bissell, D M, Wang, S S, Jarnagin, W R, Roll, F J
Expression of the group of cytokines known as transforming growth factor-beta (TGF-beta 1, -beta 2 and -beta 3) is increased during liver regeneration induced by a 70% partial hepatectomy. The origin...
Characterization of the Erwinia carotovora pelB gene and its product pectate lyase.
Lei, S P, Lin, H C, Wang, S S, Callaway, J, Wilcox, G
The pelB gene encodes pectate lyase B, one of three pectate lyases identified in Erwinia carotovora EC. Pectate lyase B was purified from Escherichia coli containing the pelB gene on a recombinant...
Melnick, J L, Wang, S S, Seidel, E, Muchinik, G, Zhang, L B, Lanford, R E
A transmissible agent, the IM virus, antigenically related to the Japanese subacute myelo-optico-neuropathy virus, has been isolated from several human cerebrospinal fluids obtained from American...
Chepelinsky, A B, Chiu, N H, Zannis-Hadjopoulos, M, Wang, S S, Martin, R G
Temperature-insensitive transformants that contained simian virus 40 sequences at only one or a few sites in the rat chromosome and that were induced by a temperature-sensitive A gene mutant of...
Detection of antibody to group B adult diarrhea rotaviruses in humans.
Nakata, S, Estes, M K, Graham, D Y, Wang, S S, Gary, G W, Melnick, J L
Group B rotaviruses have been responsible for annual epidemics of severe diarrhea affecting both adults and children in China. We developed a specific and sensitive enzyme-linked immunosorbent...
Persistence of Inoue-Melnick virus and antibody in cerebrospinal fluid.
Melnick, J L, Seidel, E, Wang, S S, Muchinik, G, Rashti, E J, Jacobs, L D, ...
Serial cerebrospinal fluid samples were obtained from 14 multiple sclerosis patients over a period of several months and were tested under code for Inoue-Melnick virus. In five of the positive...
Inhibitory effect of glucocorticoid hormones on the growth of Inoue-Melnick virus.
Inoue, Y K, Nishibe, Y, Melnick, J L, Seidel, E, Wang, S S
Glucocorticoid hormones inhibited the early stage of propagation of Inoue-Melnick virus in a dose-dependent manner in human diploid cell cultures. Prednisolone and hydrocortisone achieved complete...
Melnick, J L, Seidel, E, Wang, S S, Muchinik, G
Inoue-Melnick virus was isolated from coded cerebrospinal fluid samples from 10 of 25 patients with chronic diseases of the central nervous system. Of 13 multiple sclerosis patients and 12 patients...
Naylor, P H, Naylor, C W, Badamchian, M, Wada, S, Goldstein, A L, Wang, S S, ...
We have reported that an antiserum prepared against thymosin alpha 1 [which shares a region of homology with the p17 protein of the acquired immunodeficiency syndrome (AIDS)-associated human...
Isolation and characterization of two linked mouse U1b small nuclear RNA genes.
Marzluff, W F, Brown, D T, Lobo, S, Wang, S S
A 6.9 kilobase Eco R1 fragment containing genes for two U1 RNAs has been isolated from a library of mouse DNA. The two genes code for an RNA which is very similar, if not identical, to mouse U1b RNA...
Cationic lipid-mediated transfection of liver cells in primary culture.
Jarnagin, W R, Debs, R J, Wang, S S, Bissell, D M
We describe transfection of DNA into parenchymal and individual non-parenchymal cell populations from adult rat liver in early primary culture, using cationic lipid as the carrier. All cell...
Sequencing of Saccharomyces telomeres cloned using T4 DNA polymerase reveals two domains.
By using T4 DNA polymerase rather than S1 or Bal31 nuclease to clone yeast telomeres, very little telomeric DNA is lost. These clones were used to determine the DNA sequence of virtually the entire...
Wang, S S, Stanford, D R, Silvers, C D, Hopper, A K
STP1 is an unessential yeast gene involved in the removal of intervening sequences from some, but not all, families of intervening sequence-containing pre-tRNAs. Previously, we proposed that STP1...
Cloning and characterization of LOS1, a Saccharomyces cerevisiae gene that affects tRNA splicing.
Hurt, D J, Wang, S S, Lin, Y H, Hopper, A K
Saccharomyces cerevisiae strains carrying los1-1 mutations are defective in tRNA processing; at 37 degrees C, such strains accumulate tRNA precursors which have mature 5' and 3' ends but contain...
Isolation of a yeast gene involved in species-specific pre-tRNA processing.
To identify genes involved in pre-tRNA processing, we searched for yeast DNA sequences that specifically enhanced the expression of the SUP4(G37) gene. The SUP4(G37) gene possesses a point mutation...
Zannis-Hadjopoulos, M, Kaufmann, G, Wang, S S, Lechner, R L, Karawya, E, Hesse, J, ...
Twelve clones of monkey DNA obtained by a procedure that enriches 10(3)- to 10(4)-fold for nascent sequences activated early in S phase (G. Kaufmann, M. Zannis-Hadjopoulos, and R. G. Martin, Mol....
Proline utilization in Saccharomyces cerevisiae: analysis of the cloned PUT1 gene.
The PUT1 gene was isolated by functional complementation of a put1 (proline oxidase-deficient) mutation in Saccharomyces cerevisiae. Three independent clones with overlapping inserts of 6.8, 10.5,...
The PUT1 gene of Saccharomyces cerevisiae, believed to encode proline oxidase, has been completely sequenced and contains an open reading frame capable of encoding a polypeptide of 476 amino acids in...
Thymosin alpha1: isolation and sequence analysis of an immunologically active thymic polypeptide.
Goldstein, A L, Low, T L, McAdoo, M, McClure, J, Thurman, G B, Rossio, J, ...
The amino acid sequence of a biologically active polypeptide isolated from calf thymus, termed thymosin alpha1, has been determined. Thymosin alpha1 is a heat stable, highly acidic molecule composed...
Analytical calculation of intracellular calcium wave characteristics.
Kupferman, R, Mitra, P P, Hohenberg, P C, Wang, S S
We present a theoretical analysis of intracellular calcium waves propagated by calcium feedback at the inositol 1,4,5-trisphosphate (IP3) receptor. The model includes essential features of calcium...
Local positive feedback by calcium in the propagation of intracellular calcium waves.
In many types of eukaryotic cells, the activation of surface receptors leads to the production of inositol 1,4,5-trisphosphate and calcium release from intracellular stores. Calcium release can occur...
A-type potassium channel clusters revealed using a new statistical analysis of loose patch data.
The spatial distribution of ion channels over the surface of a neuron is an important determinant of its excitable properties. We introduce two measures of channel clustering for use in patch-clamp...
Phillips, R. L., Weber, D. F., Kleese, R. A., Wang, S. S.
Ribosomal gene compensation and magnification that might be detected on a whole-plant basis was not found in maize. Plants monosomic for chromosome 6 (the NOR chromosome) were compared with...
Bissell, D M, Wang, S S, Jarnagin, W R, Roll, F J
Expression of the group of cytokines known as transforming growth factor-beta (TGF-beta 1, -beta 2 and -beta 3) is increased during liver regeneration induced by a 70% partial hepatectomy. The origin...
Characterization of the Erwinia carotovora pelB gene and its product pectate lyase.
Lei, S P, Lin, H C, Wang, S S, Callaway, J, Wilcox, G
The pelB gene encodes pectate lyase B, one of three pectate lyases identified in Erwinia carotovora EC. Pectate lyase B was purified from Escherichia coli containing the pelB gene on a recombinant...
Melnick, J L, Wang, S S, Seidel, E, Muchinik, G, Zhang, L B, Lanford, R E
A transmissible agent, the IM virus, antigenically related to the Japanese subacute myelo-optico-neuropathy virus, has been isolated from several human cerebrospinal fluids obtained from American...
Chepelinsky, A B, Chiu, N H, Zannis-Hadjopoulos, M, Wang, S S, Martin, R G
Temperature-insensitive transformants that contained simian virus 40 sequences at only one or a few sites in the rat chromosome and that were induced by a temperature-sensitive A gene mutant of...
Detection of antibody to group B adult diarrhea rotaviruses in humans.
Nakata, S, Estes, M K, Graham, D Y, Wang, S S, Gary, G W, Melnick, J L
Group B rotaviruses have been responsible for annual epidemics of severe diarrhea affecting both adults and children in China. We developed a specific and sensitive enzyme-linked immunosorbent...
Persistence of Inoue-Melnick virus and antibody in cerebrospinal fluid.
Melnick, J L, Seidel, E, Wang, S S, Muchinik, G, Rashti, E J, Jacobs, L D, ...
Serial cerebrospinal fluid samples were obtained from 14 multiple sclerosis patients over a period of several months and were tested under code for Inoue-Melnick virus. In five of the positive...
Inhibitory effect of glucocorticoid hormones on the growth of Inoue-Melnick virus.
Inoue, Y K, Nishibe, Y, Melnick, J L, Seidel, E, Wang, S S
Glucocorticoid hormones inhibited the early stage of propagation of Inoue-Melnick virus in a dose-dependent manner in human diploid cell cultures. Prednisolone and hydrocortisone achieved complete...
Melnick, J L, Seidel, E, Wang, S S, Muchinik, G
Inoue-Melnick virus was isolated from coded cerebrospinal fluid samples from 10 of 25 patients with chronic diseases of the central nervous system. Of 13 multiple sclerosis patients and 12 patients...
Naylor, P H, Naylor, C W, Badamchian, M, Wada, S, Goldstein, A L, Wang, S S, ...
We have reported that an antiserum prepared against thymosin alpha 1 [which shares a region of homology with the p17 protein of the acquired immunodeficiency syndrome (AIDS)-associated human...
Isolation and characterization of two linked mouse U1b small nuclear RNA genes.
Marzluff, W F, Brown, D T, Lobo, S, Wang, S S
A 6.9 kilobase Eco R1 fragment containing genes for two U1 RNAs has been isolated from a library of mouse DNA. The two genes code for an RNA which is very similar, if not identical, to mouse U1b RNA...
Cationic lipid-mediated transfection of liver cells in primary culture.
Jarnagin, W R, Debs, R J, Wang, S S, Bissell, D M
We describe transfection of DNA into parenchymal and individual non-parenchymal cell populations from adult rat liver in early primary culture, using cationic lipid as the carrier. All cell...
Sequencing of Saccharomyces telomeres cloned using T4 DNA polymerase reveals two domains.
By using T4 DNA polymerase rather than S1 or Bal31 nuclease to clone yeast telomeres, very little telomeric DNA is lost. These clones were used to determine the DNA sequence of virtually the entire...
Wang, S S, Stanford, D R, Silvers, C D, Hopper, A K
STP1 is an unessential yeast gene involved in the removal of intervening sequences from some, but not all, families of intervening sequence-containing pre-tRNAs. Previously, we proposed that STP1...
Cloning and characterization of LOS1, a Saccharomyces cerevisiae gene that affects tRNA splicing.
Hurt, D J, Wang, S S, Lin, Y H, Hopper, A K
Saccharomyces cerevisiae strains carrying los1-1 mutations are defective in tRNA processing; at 37 degrees C, such strains accumulate tRNA precursors which have mature 5' and 3' ends but contain...
Isolation of a yeast gene involved in species-specific pre-tRNA processing.
To identify genes involved in pre-tRNA processing, we searched for yeast DNA sequences that specifically enhanced the expression of the SUP4(G37) gene. The SUP4(G37) gene possesses a point mutation...
Zannis-Hadjopoulos, M, Kaufmann, G, Wang, S S, Lechner, R L, Karawya, E, Hesse, J, ...
Twelve clones of monkey DNA obtained by a procedure that enriches 10(3)- to 10(4)-fold for nascent sequences activated early in S phase (G. Kaufmann, M. Zannis-Hadjopoulos, and R. G. Martin, Mol....
Proline utilization in Saccharomyces cerevisiae: analysis of the cloned PUT1 gene.
The PUT1 gene was isolated by functional complementation of a put1 (proline oxidase-deficient) mutation in Saccharomyces cerevisiae. Three independent clones with overlapping inserts of 6.8, 10.5,...
The PUT1 gene of Saccharomyces cerevisiae, believed to encode proline oxidase, has been completely sequenced and contains an open reading frame capable of encoding a polypeptide of 476 amino acids in...
Thymosin alpha1: isolation and sequence analysis of an immunologically active thymic polypeptide.
Goldstein, A L, Low, T L, McAdoo, M, McClure, J, Thurman, G B, Rossio, J, ...
The amino acid sequence of a biologically active polypeptide isolated from calf thymus, termed thymosin alpha1, has been determined. Thymosin alpha1 is a heat stable, highly acidic molecule composed...
Analytical calculation of intracellular calcium wave characteristics.
Kupferman, R, Mitra, P P, Hohenberg, P C, Wang, S S
We present a theoretical analysis of intracellular calcium waves propagated by calcium feedback at the inositol 1,4,5-trisphosphate (IP3) receptor. The model includes essential features of calcium...
Phillips, R. L., Weber, D. F., Kleese, R. A., Wang, S. S.
Ribosomal gene compensation and magnification that might be detected on a whole-plant basis was not found in maize. Plants monosomic for chromosome 6 (the NOR chromosome) were compared with...
Local positive feedback by calcium in the propagation of intracellular calcium waves.
In many types of eukaryotic cells, the activation of surface receptors leads to the production of inositol 1,4,5-trisphosphate and calcium release from intracellular stores. Calcium release can occur...
A-type potassium channel clusters revealed using a new statistical analysis of loose patch data.
The spatial distribution of ion channels over the surface of a neuron is an important determinant of its excitable properties. We introduce two measures of channel clustering for use in patch-clamp...
Wolf, B, Izenberg, H, Wang, S S
A rosette-plaque model was employed to test for the expression of b locus allelic markers at the surface of lymph node lymphocytes (LNL) from heterozygous (b4,6) rabbits, 5 days after immunization...
Wang, Y. J., Wang, S. S., Bickel, M., Guenzler, V., Gerl, M., Bissell, D. M.
The perisinusoidal stellate cells of the liver in an injury milieu undergo activation, acquiring a myofibroblast-like phenotype. In this state, they are the principal source of collagen and related...
A Java speech implementation of the Mini Mental Status Exam.
The Folstein Mini Mental Status Exam (MMSE) is a simple, widely used, verbally administered test to assess cognitive function. The Java Speech Application Programming Interface (JSAPI) is a new,...
A Web-based, secure, light weight clinical multimedia data capture and display system.
Computer-based patient records are traditionally composed of textual data. Integration of multimedia data has been historically slow. Multimedia data such as image, audio, and video have been...
Evaluation of Linear Array Human Papillomavirus Genotyping Using Automatic Optical Imaging Software▿
Jeronimo, J., Wentzensen, N., Long, R., Schiffman, M., Dunn, S. T., Allen, R. A., ...
Variations in biological behavior suggest that each carcinogenic human papillomavirus (HPV) type should be considered individually in etiologic studies. HPV genotyping assays might have clinical...
Chao, Y., Chan, W. K., Birkhofer, M. J., Hu, O. Y., Wang, S. S., Huang, Y. S., ...
Hepatocellular carcinoma (HCC) is a common lethal disease in Asia and there is no effective chemotherapy. Identification of new effective drugs in the treatment of inoperable HCC is urgently need....