S. Shaw

Publication List Details

Period

1861 - 2009

Number

188

Co-Authors

A wetland framework for impact assessment at statutory sites in England and Wales (2009)

Wheeler, B. D., Shaw, S., Tanner, K., Great Britain

The Wetland Framework project was set up as a partnership between the Wetland Research Group at the University of Sheffield, the Environment Agency, English Nature (now Natural England) and...

Earlier activity from XTE J1739-302/IGR J17391-3021 detected by INTEGRAL (2008)

Chenevez, J., Beckmann, V., Kuulkers, E., Bird, A., Brandt, S., Courvoisier, T.J.L., ...

The recently reported outburst from the supergiant fast X-ray transient XTE J1739-302/IGR J17391-3021 (ATEL #1466) began already about five hours earlier than the Swift/BAT trigger on 2008-04-08. The...

Further observations of GRO J1750-27 (AX J1749.1-2639) with INTEGRAL (2008)

Brandt, S., Shaw, S., Hill, A., Kretschmar, P., Wijnands, R., Oosterbroek, T., ...

The transient accreting X-ray pulsar GRO J1750-27 (AX J1749.1-2639), which became active end of January 2008 (ATel #1376), has been repeatedly observed by the INTEGRAL Galactic Bulge monitoring...

Recent activity of the Rapid Burster (MXB 1730-335) (2008)

Kuulkers, E., Brandt, S., Markwardt, C., Remillard, R.A., Shaw, S., Beckmann, V., ...

Observations taken as part of the INTEGRAL Galactic bulge monitoring program (see ATel #1385) on 2008, February 23 13:32-17:13 (UT) showed bursting activity from the X-ray transient, the Rapid...

Hard X-ray activity of IGR J17473-2721 (2008)

Kuulkers, E., Shaw, S., Beckmann, V., Brandt, S., Chenevez, J., Courvoisier, T.J.L., ...

Persistent X-ray activity has been reported by Swift/XRT (ATel #1459) and RXTE/PCA (ATel #1460) from the transient IGR J17473-2721 (= XTE J1747-274; ATels #467, #498) after the detection of an X-ray...

INTEGRAL spots renewed activity from H1743-322 (2008)

Kuulkers, E., Brandt, S., Budtz-Jorgensen, C., Chenevez, J., Shaw, S., Beckmann, V., ...

INTEGRAL Galactic Bulge monitoring (see ATels #438, #874, #1005, #1385) observations on UT 2008 Sep 23 08:51-12:34 reveal a new outburst of the Galactic black-hole candidate and X-ray transient...

INTEGRAL Galactic bulge monitoring observations of GRO J1750-27 (AX J1749.1-2639), H1743-322 and SLX 1746-331 (2008)

Kuulkers, E., Beckmann, V., Shaw, S., Brandt, S., Chenevez, J., Courvoisier, T.J.L., ...

A new season of the INTEGRAL Galactic Bulge monitoring program (see ATels #438, #874, #1005; Kuulkers et al. 2007, A&A 466, 595) started, with observations on UT 11 Feb 2008, 16:33-18:07. We here...

Continuous brightening of IGR J17473-2721 (2008)

Baldovin Saavedra, C., Chenevez, J., Kuulkers, E., Beckmann, V., Bird, A., Brandt, S., ...

Renewed accretion activity has been reported by Swift/XRT (ATel #1459), XTE/PCA (ATel #1460) and INTEGRAL/IBIS/ISGRI (ATel #1461) from the RXTE transient IGR J17473-2721 (= XTE J1747-274; ATels #467,...

Importance of the environment for patient acquisition of methicillin-resistant Staphylococcus aureus in the intensive care unit: a baseline study (2007)

Wilson, A.P., Hayman, S., Whitehouse, T., Cepeda, J., Kibbler, C., Shaw, S., ...

Objective: To assess the degree of environmental contamination with methicillin-resistant Staphylococcus aureus (MRSA) in critical care and the likelihood of subsequent new patient acquisition if...

The INTEGRAL Galactic Bulge monitoring program (2006)

Kuulkers, E., Shaw, S., Brandt, S., Chenevez, J., Courvoisier, T. J. -L., Ebisawa, K., ...

The Galactic Bulge region is a rich host of variable high-energy point sources. These sources include bright and relatively faint X-ray transients, X-ray bursters, persistent neutron star and...

Research governance: ethical issues (2006)

Slowther, A., Boynton, P., Shaw, S.

Health care research is haunted by a history of unethical studies in which profound harm was caused to vulnerable individuals. Official systems for gaining ethical approval for research, designed to...

Research governance: regulating risk and reducing harm? (2006)

Shaw, S., Barrett, G.

Risk assessment can be thought of as the lens through which we anticipate the consequences of research and the impact of the actions of researchers. The way in which risk of harm is managed in...

CAE and computational chemistry application performance I: benchmark studies using object-based, InfiniBand-connected storage (2006)

Deegan, M, Kelly, M, Lough, M, Shaw, S, Koeninger, RK

The I/O performance of internal disks in thin servers used in typical HPC Linux clusters can be inadequate for scratch I/O intensive applications in fields such as Computer Aided Engineering (CAE)...

Research governance: where did it come from? What does it mean? (2005)

Shaw, S., Boyton, P., Greenhalgh, T.

For a variety of historical and social reasons, research has become increasingly formalized and regulated. This change has potential benefits (reduction in fraud and misconduct, protection of...

Isolation of patients in single rooms or cohorts to reduce spread of MRSA in intensive-care units: prospective two centre study (2005)

Cepeda, J.A., Whitehouse, T., Cooper, B., Hails, J., Jones, K., Kwaku, F., ...

Background: Hospital-acquired infection due to meticillin-resistant Staphylococcus aureus (MRSA) is common within intensive-care units. Single room or cohort isolation of infected or colonised...

Announcement of INTEGRAL Galactic Bulge monitoring program and (re)brightening of GRO J1655-40 (2005)

Kuulkers, E., Shaw, S., Paizis, A., Mowlavi, N., Courvoisier, T., Ebisawa, K., ...

The Galactic Bulge is a region rich in bright and variable high-energy X-ray and gamma-ray sources. From February 17, 2005 and onwards we will observe this region regularly, using the European...

INTEGRAL observes fading of GRO J1655-40 above 20 keV (2005)

Shaw, S., Kuulkers, E., Paizis, A., Mowlavi, N., Courvoisier, T., Ebisawa, K., ...

We have observed a decrease in the the hard X-ray flux (above 20 keV) from the black hole binary GRO J1655-40, of about a factor of two (in four days), using INTEGRAL. This object has been observed...

INTEGRAL monitoring of IGR J17098-3628 (2005)

Mowlavi, N., Kuulkers, E., Rodriguez, J., Shaw, S., Paizis, A., Courvoisier, T., ...

IGR J17098-3628 (ATEL #444) has been observed by INTEGRAL in the Galactic Bulge Monitoring program (ATEL #438). We detected the source with ISGRI in observations during 2005, March 26 00:00, April 2...

Workplace diversity: The moderating role of work context on the relationship between surface and deep level diversity and group functioning (2005)

Shaw, S., Sheehan, A., Martin, R.

This research examines the relationship between perceived group diversity and group conflict, and the moderating role of team context. Currentiy, diversity research predominantly focuses on surface...

Under-use of beta-blockers in patients with ischaemic heart disease and concomitant chronic obstructive pulmonary disease (2005)

Egred, M., Shaw, S., Mohammad, B., Waitt, P., Rodrigues, E.

Background: Beta-blockers (BB) improve morbidity and mortality in ischaemic heart disease. There is a general reluctance to use BB, especially in patients with chronic obstructive pulmonary disease...

Under-use of beta-blockers in patients with ischaemic heart disease and concomitant chronic obstructive pulmonary disease (2005)

Egred, M., Shaw, S., Mohammad, B., Waitt, P., Rodrigues, E.

Background: Beta-blockers (BB) improve morbidity and mortality in ischaemic heart disease. There is a general reluctance to use BB, especially in patients with chronic obstructive pulmonary disease...

Bayes linear kinematics and Bayes linear Bayes graphical models. (2004)

Goldstein, M., Shaw, S.

Probability kinematics (Jeffrey, 1965, 1983) furnishes a method for revising a prior probability specification based upon new probabilities over a partition.We develop a corresponding Bayes linear...

GRS 1915+105: The first three months with INTEGRAL (2004)

Hannikainen, D. C., Vilhu, O., Rodriguez, J., Westergaard, N. J., Shaw, S., Pooley, G. G., ...

GRS 1915+105 is being observed as part of an Open Time monitoring program with INTEGRAL. Three out of six observations from the monitoring program are presented here, in addition to data obtained...

The sky behind our galaxy as seen by IBIS on INTEGRAL (2004)

Bassani, L., Malizia, A., Stephen, J. B., Gianotti, F., Schiavone, F., Bazzano, A., ...

During the Core Programme, INTEGRAL has surveyed a large portion of the sky (around 9000 square degrees); although INTEGRAL is not optimized for extra-galactic studies its observations have...

Transition to a hard state of 1RXP J130159.6-635806 (2004)

Chernyakova, M., Shtykovsky, P., Lutovinov, A., Revnivtsev, M., Courvoisier, T., Walter, R., ...

We report a detection of a transition to a hard state during the possible outburst of a ROSAT source 1RXP J130159.6-635806, located approximately 10 arc minutes from PSR 1259-63. Source was observed...

Neither market failure nor customer ignorance: the organizational limitations of employee training and development (2003)

Taylor, Scott, Thorpe, Richard, Shaw, S.

In its description and analysis of the current context of research and practice of HRD in small organizations, this collection of essays provides a comprehensive and critical evaluation of current...

Routine patch testing with frullanolide mix: an European Environmental and Contact Dermatitis Research Group multicentre study (2003)

Lepoittevin, J P, Berl, V, Andersen, K E, Brandão, F M, Bruynzeel, D P, ...

Contact sensitivity to plants containing 1 or more sesquiterpene lactones (SLs) is difficult to diagnose. The mixture of SLs (SL mix) has been shown to detect only about 60% of sensitized...

Human resource management: managing people in smaller oganisations (2003)

Taylor, Scott, Shaw, S., Atkinson, S.

Draws on up-to-date empirical evident to illustrate how SMEs can become more innovative through the introduction of new products and services. Discusses the effective and efficient use of information...

Monitoring levels of preservative sensitivity in Europe. A 10-year overview (1991-2000) (2002)

Shaw, S, Andersen, K E, Brandao, F M, Bruynzeel, D P, Bruze, M, ...

A 10-year multicentre analysis of the frequency of sensitivity to common preservatives collected in 16 centres in 11 countries has shown stable but persisting high levels of sensitivity to...

Use of ultramolecular potencies of allergen to treat asthmatic people allergic to house dust mite: double blind randomised controlled clinical trial (2002)

Lewith, G.T., Watkins, A.D., Hyland, M.E., Shaw, S., Broomfield, J.A., Dolan, G., ...

Objective: To evaluate the efficacy of homoeopathic immunotherapy on lung function and respiratory symptoms in asthmatic people allergic to house dust mite. Design: Double blind randomised controlled...

Use of ultramolecular potencies of allergen to treat asthmatic people allergic to house dust mite: double blind randomised controlled clinical trial (2002)

Lewith, G.T., Watkins, A.D., Hyland, M.E, Shaw, S., Broomfield, J.A., Dolan, G., ...

OBJECTIVE: To evaluate the efficacy of homoeopathic immunotherapy on lung function and respiratory symptoms in asthmatic people allergic to house dust mite. DESIGN: Double blind randomised controlled...

Use of ultramolecular potencies of allergen to treat asthmatic people allergic to house dust mite: double blind randomised controlled clinical trial (2002)

Lewith, G.T., Shaw, S., Broomfield, J.A., Dolan, G., Holgate, S.T.

OBJECTIVE: To evaluate the efficacy of homoeopathic immunotherapy on lung function and respiratory symptoms in asthmatic people allergic to house dust mite. DESIGN: Double blind randomised controlled...

Patch testing with corticosteroid mixes in Europe. A multicentre study of the EECDRG (2000)

Andersen, K E, Brandão, F M, Bruynzeel, D P, Bruze, M, Camarasa, J G, ...

This study investigated whether a corticosteroid mix containing tixocortol pivalate, budesonide, and hydrocortisone-17-butyrate could detect contact allergy to corticosteroids. 2 corticosteroid...

Nitric oxide prevents cardiovascular disease and determines survival in polyglobulic mice overexpressing erythropoietin. (2000)

Ruschitzka, F T, Wenger, R H, Stallmach, T, Quaschning, T, De Wit, C, Wagner, K, ...

Nitric oxide (NO) induces vasodilatatory, antiaggregatory, and antiproliferative effects in vitro. To delineate potential beneficial effects of NO in preventing vascular disease in vivo, we generated...

Routine patch testing with the sesquiterpene lactone mix in Europe: a 2-year experience. A multicentre study of the EECDRG (1999)

Andersen, K E, Brandão, F M, Bruynzeel, D P, Ducombs, G, Frosch, P J, ...

To test the screening value of the sesquiterpene lactone (SL) mix in Europe today and describe epidemiological and clinical features of Compositae-sensitive patients, the SL mix 0.1% pet. was...

Robust Adaptive Finite Element Schemes for Nonlinear Viscoelastic Solid Deformation: An Investigative Study (1998)

Whiteman, J. R., Shaw, S.

In this first three month phase of the research project we have continued our existing work, as outlined in the original Seed Project Proposal, on the numerical solution of quasistatic...

Robust Adaptive Finite Element Schemes for Nonlinear Viscoelastic Solid Deformation: An Investigative Study (1998)

Whiteman, J. R., Shaw, S.

During this second three month phase of the seed project we have consolidated the phase 1 work on the Volterra formulation of linear quasistatic viscoelasticity problems, and three papers have now...

Numerical Techniques for the Treatment of Quasistatic Solid Viscoelastic Stress Problems (1998)

Shaw, S., Warby, M. K., Whiteman, J. R., Dawson, C., Wheeler, M. F.

For quasistatic stress problems two alternative constitutive relationships expressing the stress in a linear viscoelastic solid body as a linear functional of the strain are derived. In conjunction...

Kidney transplantation decreases the tissue level of advanced glycosylation end-products (1995)

Lee, W. K., Akyol, M., Shaw, S., Dominiczak, M. H., Briggs, J. D.

We have studied the effect of chronic renal failure (CRF) and kidney transplantation on advanced glycosylation end-products (AGE) measured as collagen-linked fluorescence (CLF) in the skin and...

An Error Bound via the Ritz-Volterra Projection for a Fully Discrete Approximation to a Hyperbolic Integrodifferential Equation (1994)

S. Shaw, M. K. Warby, J. R. Whiteman

. A fully discrete scheme for approximating a second order hyperbolic Volterra integrodifferential equation of the second kind is proposed. The discretization is accomplished by applying the finite...

Shellfish culture in Europe (1993)

ANTONA, Martine, BAILLY, Denis, PAQUOTTE, Philippe, GABOTT, M, GIBBS, J, SHAW, S, ...

This report includes a qualitative and descriptive approach of the oyster and mussel industries in the European Community. This report compares the structure of production, the marketsn the...

European aquaculture 1991 (1991)

SHAW, S

Aquaculture, the farming of aquatic animals and plants in marine and freshwater, has become a major industry in the Member States of the European Community. It is estimated that total production in...

Einrichtung zum Anbringen eines Schallempfaengers an einer Anschlussstelle einer Fluessigkeitsleitung (1985)

Fuchs, H.V., Shaw, S., Schmidt Schykowski, K.

Bei einer bekannten Einrichtung zum Anbringen eines Schallempfaengers an einer Abzweigleitung eines Fluessigkeitsrohrnetzes befindet sich der Schallempfaenger am Ende eines mit einer Anschlussstelle...

Data Processing at the INTEGRAL Science Data Centre

Beck, M, Aubord, A, Bartholdi, P, Beckmann, V, Binko, P, Borkowski, J, ...

INTEGRAL, the INTErnational Gamma Ray Astrophysics Laboratory of the European Space Agency, was launched on October 17, 2002. INTEGRAL operations are performed very successfully and the instruments...

Hepatocyte growth factor and macrophage inflammatory protein 1 beta: structurally distinct cytokines that induce rapid cytoskeletal changes and subset-preferential migration in T cells.

Adams, D H, Harvath, L, Bottaro, D P, Interrante, R, Catalano, G, Tanaka, Y, ...

T-cell migration into tissue depends on a cascade of rapid and selective adhesive interactions with endothelium. "Triggering" is a step in that cascade required to activate T-cell integrins....

The paradox of Hemophilus infuenzae type B bacteremia in the presence of serum bactericidal activity.

Shaw, S, Smith, A L, Anderson, P, Smith, D H

We investigated the role of serum bactericidal activity in Hemophiplus influenzae type b infections in infants with meningitis and in a rat model. In infected infants, 13/22 admission sera had...

Killing of measles virus-infected cells by human cytotoxic T cells.

Lucas, C J, Biddison, W E, Nelson, D L, Shaw, S

Lymphocytes from normal individuals were tested for the capacity to generate measles virus-specific cytotoxic T-cell responses after in vitro stimulation with measles virus. Approximately 12% (5 of...

Transfer of cloned human class I major histocompatibility complex genes into HLA mutant human lymphoblastoid cells.

Shimizu, Y, Koller, B, Geraghty, D, Orr, H, Shaw, S, Kavathas, P, ...

Three new kinds of recombinant DNA constructs were used to transfer cloned human class I HLA genes (A2 and B8) into unique HLA mutant lymphoblastoid cells: pHeBo(x): a class I gene, "x," in plasmid...

Blood levels and renal effects of atrial natriuretic peptide in normal man.

Weidmann, P, Hasler, L, Gnädinger, M P, Lang, R E, Uehlinger, D E, Shaw, S, ...

Since mammalian atria were recently found to contain vasoactive and natriuretic peptides, we investigated the following in normal humans: plasma human atrial natriuretic peptide concentrations,...

Evidence for alteration of the vitamin D-endocrine system in obese subjects.

Bell, N H, Epstein, S, Greene, A, Shary, J, Oexmann, M J, Shaw, S

Serum immunoreactive parathyroid hormone (PTH) is increased in obese as compared with nonobese subjects and declines with weight loss. To determine whether alteration of the vitamin D-endocrine...

Evidence for alteration of the vitamin D-endocrine system in blacks.

Bell, N H, Greene, A, Epstein, S, Oexmann, M J, Shaw, S, Shary, J

As compared with values in white subjects, bone mass is known to be increased and urinary calcium to be diminished in black individuals. To evaluate the possibility that these changes are associated...

Inhibitory effect of a human T cell hybrid factor on both cell growth and mixed lymphocyte reactivity. Correlation with class II molecule expression.

Trucco, M, Shaw, S, Korngold, R

We recently reported the biological activity and some of the biochemical characteristics of a factor produced by a human T cell hybrid clone able to block hematopoietic progenitor cell proliferation....

Evidence that 1,25-dihydroxyvitamin D3 inhibits the hepatic production of 25-hydroxyvitamin D in man.

Bell, N H, Shaw, S, Turner, R T

Previous in vitro studies in rachitic rat liver suggested that 1,25-dihydroxyvitamin D inhibits the hepatic production of 25-hydroxyvitamin D (25-OHD). An investigation therefore was carried out in...

Laboratory studies on patients receiving anticoagulant therapy

Shaw, S., Pegrum, G. D., Wolff, S.

An investigation into the laboratory control of anticoagulant therapy is presented. The cases were divided into those in the first few weeks of therapy and those on long-term treatment. Variations in...

Measurement of platelet adhesiveness including the use of diatomaceous silica (celite)

Pegrum, G. D., Shaw, S., Wolff, Sylvia E.

Methods of platelet adhesiveness to glass and celite have been developed. The technical merits of these methods have been compared with a method using adenosine diphosphate (ADP). The aspects of...

Platelet adhesiveness in diabetes mellitus

Shaw, S., Pegrum, G. D., Wolff, Sylvia, Ashton, W. L.

Platelet adhesiveness has been assessed on whole blood from a series of 34 diabetics and 50 control subjects using adenosine diphosphate (A.D.P.) and by adherence to glass microspherules (ballotini)....

The role of aldehyde oxidase in ethanol-induced hepatic lipid peroxidation in the rat.

Shaw, S, Jayatilleke, E

Hepatic lipid peroxidation has been implicated in the pathogenesis of alcohol-induced liver injury, but the mechanism(s) by which ethanol metabolism or resultant free radicals initiate lipid...

Cleavage of folates during ethanol metabolism. Role of acetaldehyde/xanthine oxidase-generated superoxide.

Shaw, S, Jayatilleke, E, Herbert, V, Colman, N

Although folate deficiency and increased requirements for folate are observed in most alcoholics, the possibility that acetaldehyde generated from ethanol metabolism may increase folate catabolism...

Semen contact urticaria.

Poskitt, B L, Wojnarowska, F T, Shaw, S

An allergic reaction to human seminal fluid was first reported by Halpern et al. 1967. Since then there have been more than 30 cases recorded in the literature but it remains a rare cause of...

Linkage of bipolar affective disorder to chromosome 18 markers in a new pedigree series.

McMahon, F J, Hopkins, P J, Xu, J, McInnis, M G, Shaw, S, Cardon, L, ...

Several groups have reported evidence suggesting linkage of bipolar affective disorder (BPAD) to chromosome 18. We have reported data from 28 pedigrees that showed linkage to marker loci on 18p and...

Career changes among Saskatchewan physicians.

Shaw, S, Goplen, G, Houston, D S

OBJECTIVE: To determine how often Saskatchewan physicians changed career paths during medical training and practice. DESIGN: Population survey (mailed questionnaire). SETTING: Saskatchewan....

Hepatocyte growth factor and macrophage inflammatory protein 1 beta: structurally distinct cytokines that induce rapid cytoskeletal changes and subset-preferential migration in T cells.

Adams, D H, Harvath, L, Bottaro, D P, Interrante, R, Catalano, G, Tanaka, Y, ...

T-cell migration into tissue depends on a cascade of rapid and selective adhesive interactions with endothelium. "Triggering" is a step in that cascade required to activate T-cell integrins....

The paradox of Hemophilus infuenzae type B bacteremia in the presence of serum bactericidal activity.

Shaw, S, Smith, A L, Anderson, P, Smith, D H

We investigated the role of serum bactericidal activity in Hemophiplus influenzae type b infections in infants with meningitis and in a rat model. In infected infants, 13/22 admission sera had...

Killing of measles virus-infected cells by human cytotoxic T cells.

Lucas, C J, Biddison, W E, Nelson, D L, Shaw, S

Lymphocytes from normal individuals were tested for the capacity to generate measles virus-specific cytotoxic T-cell responses after in vitro stimulation with measles virus. Approximately 12% (5 of...

Transfer of cloned human class I major histocompatibility complex genes into HLA mutant human lymphoblastoid cells.

Shimizu, Y, Koller, B, Geraghty, D, Orr, H, Shaw, S, Kavathas, P, ...

Three new kinds of recombinant DNA constructs were used to transfer cloned human class I HLA genes (A2 and B8) into unique HLA mutant lymphoblastoid cells: pHeBo(x): a class I gene, "x," in plasmid...

Blood levels and renal effects of atrial natriuretic peptide in normal man.

Weidmann, P, Hasler, L, Gnädinger, M P, Lang, R E, Uehlinger, D E, Shaw, S, ...

Since mammalian atria were recently found to contain vasoactive and natriuretic peptides, we investigated the following in normal humans: plasma human atrial natriuretic peptide concentrations,...

Evidence for alteration of the vitamin D-endocrine system in obese subjects.

Bell, N H, Epstein, S, Greene, A, Shary, J, Oexmann, M J, Shaw, S

Serum immunoreactive parathyroid hormone (PTH) is increased in obese as compared with nonobese subjects and declines with weight loss. To determine whether alteration of the vitamin D-endocrine...

Evidence for alteration of the vitamin D-endocrine system in blacks.

Bell, N H, Greene, A, Epstein, S, Oexmann, M J, Shaw, S, Shary, J

As compared with values in white subjects, bone mass is known to be increased and urinary calcium to be diminished in black individuals. To evaluate the possibility that these changes are associated...

Inhibitory effect of a human T cell hybrid factor on both cell growth and mixed lymphocyte reactivity. Correlation with class II molecule expression.

Trucco, M, Shaw, S, Korngold, R

We recently reported the biological activity and some of the biochemical characteristics of a factor produced by a human T cell hybrid clone able to block hematopoietic progenitor cell proliferation....

Evidence that 1,25-dihydroxyvitamin D3 inhibits the hepatic production of 25-hydroxyvitamin D in man.

Bell, N H, Shaw, S, Turner, R T

Previous in vitro studies in rachitic rat liver suggested that 1,25-dihydroxyvitamin D inhibits the hepatic production of 25-hydroxyvitamin D (25-OHD). An investigation therefore was carried out in...

Laboratory studies on patients receiving anticoagulant therapy

Shaw, S., Pegrum, G. D., Wolff, S.

An investigation into the laboratory control of anticoagulant therapy is presented. The cases were divided into those in the first few weeks of therapy and those on long-term treatment. Variations in...

Measurement of platelet adhesiveness including the use of diatomaceous silica (celite)

Pegrum, G. D., Shaw, S., Wolff, Sylvia E.

Methods of platelet adhesiveness to glass and celite have been developed. The technical merits of these methods have been compared with a method using adenosine diphosphate (ADP). The aspects of...

Platelet adhesiveness in diabetes mellitus

Shaw, S., Pegrum, G. D., Wolff, Sylvia, Ashton, W. L.

Platelet adhesiveness has been assessed on whole blood from a series of 34 diabetics and 50 control subjects using adenosine diphosphate (A.D.P.) and by adherence to glass microspherules (ballotini)....

The role of aldehyde oxidase in ethanol-induced hepatic lipid peroxidation in the rat.

Shaw, S, Jayatilleke, E

Hepatic lipid peroxidation has been implicated in the pathogenesis of alcohol-induced liver injury, but the mechanism(s) by which ethanol metabolism or resultant free radicals initiate lipid...

Cleavage of folates during ethanol metabolism. Role of acetaldehyde/xanthine oxidase-generated superoxide.

Shaw, S, Jayatilleke, E, Herbert, V, Colman, N

Although folate deficiency and increased requirements for folate are observed in most alcoholics, the possibility that acetaldehyde generated from ethanol metabolism may increase folate catabolism...

Semen contact urticaria.

Poskitt, B L, Wojnarowska, F T, Shaw, S

An allergic reaction to human seminal fluid was first reported by Halpern et al. 1967. Since then there have been more than 30 cases recorded in the literature but it remains a rare cause of...

Career changes among Saskatchewan physicians.

Shaw, S, Goplen, G, Houston, D S

OBJECTIVE: To determine how often Saskatchewan physicians changed career paths during medical training and practice. DESIGN: Population survey (mailed questionnaire). SETTING: Saskatchewan....

Linkage of bipolar affective disorder to chromosome 18 markers in a new pedigree series.

McMahon, F J, Hopkins, P J, Xu, J, McInnis, M G, Shaw, S, Cardon, L, ...

Several groups have reported evidence suggesting linkage of bipolar affective disorder (BPAD) to chromosome 18. We have reported data from 28 pedigrees that showed linkage to marker loci on 18p and...

Immune enhancing effects of dehydroepiandrosterone and dehydroepiandrosterone sulphate and the role of steroid sulphatase.

Suitters, A J, Shaw, S, Wales, M R, Porter, J P, Leonard, J, Woodger, R, ...

Steroid hormones, such as glucocorticoids (GC), influence immune and inflammatory responses through their suppressive actions. Recent evidence suggests that another steroid hormone,...

Presbyopic phacovitrectomy

Ling, R, Simcock, P, McCoombes, J, Shaw, S

Aim: To review the results and complications of combined phacoemulsification and vitrectomy in presbyopic patients.

Suprachoroidal haemorrhage complicating cataract surgery in the UK: a case control study of risk factors

Ling, R, Kamalarajah, S, Cole, M, James, C, Shaw, S

Aims: To study the risk factors for suprachoroidal haemorrhage (SCH) complicating cataract surgery in the United Kingdom.

Suprachoroidal haemorrhage complicating cataract surgery in the UK: epidemiology, clinical features, management, and outcomes

Ling, R, Cole, M, James, C, Kamalarajah, S, Foot, B, Shaw, S

Aims: To study the incidence, management, and outcomes of suprachoroidal haemorrhage (SCH) complicating cataract surgery in the United Kingdom.

Reduced frequency of nickel allergy upon oral nickel contact at an early age

Andersen, K. E., Boden, D., Bruynzeel, D. P., Burrows, D., ...

From animal studies we know that oral administration of T-dependent antigens before sensitization effectively induces systemic immune unresponsiveness. Such `oral tolerance' is persistent,...

The cardiodepressant and vasodepressant effects of tumour necrosis factor in rat isolated atrial and aortic tissues.

Foulkes, R., Shaw, S.

1. The ability of recombinant human tumour necrosis factor-alpha (rec huTNF) to elicit cardiodepressor and vasodepressor effects in rat isolated tissues was investigated. 2. rec huTNF (3 x 10(-11)-3...

Molecular characterisation of the 22q13 deletion syndrome supports the role of haploinsufficiency of SHANK3/PROSAP2 in the major neurological symptoms

Wilson, H, Wong, A, Shaw, S, Tse, W, Stapleton, G, Phelan, M, ...

Methods: The 22q13 deletion syndrome (MIM 606232) is characterised by moderate to profound mental retardation, delay/absence of expressive speech, hypotonia, normal to accelerated growth, and mild...

Controlled randomised crossover trial of the effects of physiotherapy on mobility in chronic multiple sclerosis

Wiles, C, Newcombe, R, Fuller, K, Shaw, S, Furnival-Doran, J, Pickersgill, T, ...

OBJECTIVES—To determine whether physiotherapy can improve mobility in chronic multiple sclerosis and whether there is a difference between treatment at home and as a hospital...

Alpha and beta chains of SB and DR antigens are structurally distinct

Hurley, CK, Shaw, S, Nadler, L, Schlossman, S, Capra, JD

Limited amino-terminal amino acid sequences of the HLA-controlled SB and DR antigens from the cell line PREISS (DR4/4, SB3/4) show differences in both the alpha and beta chain sequences of the two...

Allergic contact dermatitis to acrylates in disposable blue diathermy pads.

Sidhu, S. K., Shaw, S.

We report 2 cases of elicitation of allergic contact dermatitis to acrylates from disposable blue diathermy pads used on patients who underwent routine surgery. Their reactions were severe, and took...

Portal hypertension in a patient with chronic myeloid leukaemia.

Foadi, M. D., Shaw, S., Paradinas, F. J.

A patient with chronic myeloid leukaemia treated with busulphan for 4-5 years, developed signs of busulphan toxicity and portal hypertension with ascites, oesophageal varices and jaundice. At...

The value of serum neopterin, interferon-gamma levels and interleukin-12B polymorphisms in predicting acute renal allograft rejection

Chin, G K, Adams, C L, Carey, B S, Shaw, S, Tse, W-Y, Kaminski, E R

Acute rejection remains a poor predictor of graft outcome. In this study, we measured serum levels of interferon (IFN)-γ and neopterin by enzyme-linked immunosorbent assay and a single nucleotide...

Interleukin 12B gene polymorphism and apparent resistance to hepatitis C virus infection

Hegazy, D, Thurairajah, P, Metzner, M, Houldsworth, A, Shaw, S, Kaminski, E, ...

Cellular immunity with interferon gamma production could have a role in protection from hepatitis C virus (HCV). Interleukin (IL)-12 is a key cytokine in promoting such anti-viral T helper 1 (Th1)...

Adhesion of tumour-infiltrating lymphocytes to endothelium: a phenotypic and functional analysis.

Adams, D. H., Yannelli, J. R., Newman, W., Lawley, T., Ades, E., Rosenberg, S. A., ...

Efficacy of cancer immunotherapy with cultured tumour-infiltrating lymphocytes (TILs) depends upon infused TILs migrating into tumour-bearing tissue, in which they mediate an anti-tumour response....