Modular Structure of Glucocorticoid Receptor Domains Is Not (2008)
Equivalent To Functional, Min Xu, Pradip K. Chakraborti, Michael J. Garabedian, Keith R. Yamamoto, S. Stoney Simons
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Anzick, Sarah L, Azorsa, David O, Simons, S Stoney, Meltzer, Paul S
Abstract Background Estrogen signaling plays a critical role in a number of normal physiological processes and has important implications in the treatment of breast cancer. The p160 nuclear receptor...
Zeng, Huawei, Kaul, Sunil, Simons, S. Stoney
The glucocorticoid modulatory element binding proteins 1 and 2 (GMEB-1 and GMEB-2) are of interest both for their multiple activities (e.g. modulation of transactivation by the glucocorticoid...
Receptor Associated Proteins Resource. The goal of (1996)
Elisabeth Martinez, David D. Moore, Evan Keller, David Pearce, Vincent Robinson, Paul N. Macdonald, ...
We have expanded the original Glucocorticoid Receptor Resource (GRR) database to include several individual resources as part of a larger project called the Nuclear Receptor Resource (NRR). In...
Zeng, Huawei, Kaul, Sunil, Simons, S. Stoney
The glucocorticoid modulatory element binding proteins 1 and 2 (GMEB-1 and GMEB-2) are of interest both for their multiple activities (e.g. modulation of transactivation by the glucocorticoid...
Anthrax lethal factor represses glucocorticoid and progesterone receptor activity
Webster, Jeanette I., Tonelli, Leonardo H., Moayeri, Mahtab, Simons, S. Stoney, Leppla, Stephen H., Sternberg, Esther M.
We report here that a bacterial toxin, anthrax lethal toxin (LeTx), at very low concentrations represses glucocorticoid receptor (GR) transactivation in a transient transfection system and the...
Phenotypic alterations in breast cancer cells overexpressing the nuclear receptor co-activator AIB1
Anzick, Sarah L, Azorsa, David O, Simons, S Stoney, Meltzer, Paul S
Zeng, Huawei, Kaul, Sunil, Simons, S. Stoney
The glucocorticoid modulatory element binding proteins 1 and 2 (GMEB-1 and GMEB-2) are of interest both for their multiple activities (e.g. modulation of transactivation by the glucocorticoid...
Anthrax lethal factor represses glucocorticoid and progesterone receptor activity
Webster, Jeanette I., Tonelli, Leonardo H., Moayeri, Mahtab, Simons, S. Stoney, Leppla, Stephen H., Sternberg, Esther M.
We report here that a bacterial toxin, anthrax lethal toxin (LeTx), at very low concentrations represses glucocorticoid receptor (GR) transactivation in a transient transfection system and the...
Phenotypic alterations in breast cancer cells overexpressing the nuclear receptor co-activator AIB1
Anzick, Sarah L, Azorsa, David O, Simons, S Stoney, Meltzer, Paul S
He, Yuanzheng, Simons, S. Stoney
The coactivator TIF2 was predicted to interact with an unknown factor to modify both the relative inhibition in glucocorticoid receptor (GR)-mediated gene repression and several parameters of...
Doubling the Size of the Glucocorticoid Receptor Ligand Binding Pocket by Deacylcortivazolâ–¿
Suino-Powell, Kelly, Xu, Yong, Zhang, Chenghai, Tao, Yong-guang, Tolbert, W. David, Simons, S. Stoney, ...
A common feature of nuclear receptor ligand binding domains (LBD) is a helical sandwich fold that nests a ligand binding pocket within the bottom half of the domain. Here we report that the ligand...