S. Toyoshima

Publication List Details

Number

20

Co-Authors

Characterization of a GTP-binding protein implicated in both memory storage and interorganelle vesicle transport.

Nelson, T J, Yoshioka, T, Toyoshima, S, Han, Y F, Alkon, D L

The phosphorylation state of cp20, a low molecular weight GTP-binding protein that is a high-affinity substrate for protein kinase C, was previously shown to change after associative conditioning of...

Mechanism of inactivation of hepatitis B surface antigen by N alpha-cocoyl-L-arginine ethyl ester.

Sugimoto, Y, Toyoshima, S

The mechanism of N alpha-cocoyl-L-arginine ethyl ester (CAE) in the inactivation of hepatitis B surface antigen (HBsAg) was investigated. The CAE increased the density of HBsAg, and particles of the...

Morphological varieties and host ranges of Vibrio parahaemolyticus bacteriophages isolated from seawater.

Koga, T, Toyoshima, S, Kawata, T

Eighteen bacteriophages lytic for Vibrio parahaemolyticus were isolated from seawater, and their ultrastructure was examined by electron microscopy. Based on the phage morphology, they were...

Influence of chemical modification of N alpha-cocoyl-L-arginine ethyl ester on its hepatitis B surface antigen-inactivating effect.

Sugimoto, Y, Toyoshima, S

We have reported previously that N alpha-cocoyl-L-arginine ethyl ester (CAE) strongly inactivates hepatitis B surface antigen (HBsAg; Sugimoto and Toyoshima, Antimicrob. Agents Chemother....

Phospholipid methylation: a biochemical signal modulating lymphocyte mitogenesis.

Hirata, F, Toyoshima, S, Axelrod, J, Waxdal, M J

Phospholipid methylation in murine T lymphocytes but not B cells was stimulated by mitogenic lectins such as concanavalin A and phytohemagglutinin, and the methylation was then returned to the...

N-alpha-Cocoyl-L-arginine ethyl ester, DL-pyroglutamic acid salt, as an inactivator of hepatitis B surface antigen.

Sugimoto, Y, Toyoshima, S

N-alpha-Cocoyl-L-arginine ethyl ester, DL-pyroglutamic acid salt (CAE), exhibited a strong inactivating effect on hepatitis B surface antigen. Concentrations of CAE required for 50 and 100%...

Transcriptional regulation of the c-jun gene by retinoic acid and E1A during differentiation of F9 cells.

Kitabayashi, I, Kawakami, Z, Chiu, R, Ozawa, K, Matsuoka, T, Toyoshima, S, ...

Differentiation of mouse F9 embryonal carcinoma (EC) cells can be induced by exposure to retinoic acid (RA) or by expression of adenovirus E1A. The transcription of the c-jun gene is stimulated by...

Concanavalin A-induced receptor aggregation stimulates the tyrosine kinase activity of the insulin receptor in intact cells.

Shiba, T, Tobe, K, Koshio, O, Yamamoto, R, Shibasaki, Y, Matsumoto, N, ...

Concanavalin A (ConA) stimulated the phosphorylation of the beta-subunit of the insulin receptor and an Mr-185,000 protein on serine and tyrosine residues in intact H-35 rat hepatoma cells. This...

Isolation and partial characterization of the major sialoglycoprotein of human T-lymphoblastoid cells of a MOLT-4B cell line.

Saito, M, Toyoshima, S, Osawa, T

A sialoglycoprotein with an approx. mol.wt. of 95000 was isolated from human lymphoblastoid cells of a MOLT-4B cell line, which was of human T-lymphocyte origin, by ion-exchange chromatography,...

Mutation of tyrosine-194 and lysine-198 in the catalytic site of pig 3alpha/beta,20beta-hydroxysteroid dehydrogenase.

Nakajin, S, Takase, N, Ohno, S, Toyoshima, S, Baker, M E

Pig 3alpha/beta,20beta-hydroxysteroid dehydrogenase is an NADPH-dependent enzyme that catalyses the reduction of ketones on steroids and aldehydes and ketones on various xenobiotics, like its...

Characterization of a GTP-binding protein implicated in both memory storage and interorganelle vesicle transport.

Nelson, T J, Yoshioka, T, Toyoshima, S, Han, Y F, Alkon, D L

The phosphorylation state of cp20, a low molecular weight GTP-binding protein that is a high-affinity substrate for protein kinase C, was previously shown to change after associative conditioning of...

Mechanism of inactivation of hepatitis B surface antigen by N alpha-cocoyl-L-arginine ethyl ester.

Sugimoto, Y, Toyoshima, S

The mechanism of N alpha-cocoyl-L-arginine ethyl ester (CAE) in the inactivation of hepatitis B surface antigen (HBsAg) was investigated. The CAE increased the density of HBsAg, and particles of the...

Morphological varieties and host ranges of Vibrio parahaemolyticus bacteriophages isolated from seawater.

Koga, T, Toyoshima, S, Kawata, T

Eighteen bacteriophages lytic for Vibrio parahaemolyticus were isolated from seawater, and their ultrastructure was examined by electron microscopy. Based on the phage morphology, they were...

Influence of chemical modification of N alpha-cocoyl-L-arginine ethyl ester on its hepatitis B surface antigen-inactivating effect.

Sugimoto, Y, Toyoshima, S

We have reported previously that N alpha-cocoyl-L-arginine ethyl ester (CAE) strongly inactivates hepatitis B surface antigen (HBsAg; Sugimoto and Toyoshima, Antimicrob. Agents Chemother....

Phospholipid methylation: a biochemical signal modulating lymphocyte mitogenesis.

Hirata, F, Toyoshima, S, Axelrod, J, Waxdal, M J

Phospholipid methylation in murine T lymphocytes but not B cells was stimulated by mitogenic lectins such as concanavalin A and phytohemagglutinin, and the methylation was then returned to the...

N-alpha-Cocoyl-L-arginine ethyl ester, DL-pyroglutamic acid salt, as an inactivator of hepatitis B surface antigen.

Sugimoto, Y, Toyoshima, S

N-alpha-Cocoyl-L-arginine ethyl ester, DL-pyroglutamic acid salt (CAE), exhibited a strong inactivating effect on hepatitis B surface antigen. Concentrations of CAE required for 50 and 100%...

Transcriptional regulation of the c-jun gene by retinoic acid and E1A during differentiation of F9 cells.

Kitabayashi, I, Kawakami, Z, Chiu, R, Ozawa, K, Matsuoka, T, Toyoshima, S, ...

Differentiation of mouse F9 embryonal carcinoma (EC) cells can be induced by exposure to retinoic acid (RA) or by expression of adenovirus E1A. The transcription of the c-jun gene is stimulated by...

Concanavalin A-induced receptor aggregation stimulates the tyrosine kinase activity of the insulin receptor in intact cells.

Shiba, T, Tobe, K, Koshio, O, Yamamoto, R, Shibasaki, Y, Matsumoto, N, ...

Concanavalin A (ConA) stimulated the phosphorylation of the beta-subunit of the insulin receptor and an Mr-185,000 protein on serine and tyrosine residues in intact H-35 rat hepatoma cells. This...

Isolation and partial characterization of the major sialoglycoprotein of human T-lymphoblastoid cells of a MOLT-4B cell line.

Saito, M, Toyoshima, S, Osawa, T

A sialoglycoprotein with an approx. mol.wt. of 95000 was isolated from human lymphoblastoid cells of a MOLT-4B cell line, which was of human T-lymphocyte origin, by ion-exchange chromatography,...

Mutation of tyrosine-194 and lysine-198 in the catalytic site of pig 3alpha/beta,20beta-hydroxysteroid dehydrogenase.

Nakajin, S, Takase, N, Ohno, S, Toyoshima, S, Baker, M E

Pig 3alpha/beta,20beta-hydroxysteroid dehydrogenase is an NADPH-dependent enzyme that catalyses the reduction of ketones on steroids and aldehydes and ketones on various xenobiotics, like its...