S. Tsuji

Publication List Details

Period

1991 - 9999

Number

66

Co-Authors

Settlement of Three Buildings on Piled Foundations (9999)

Kishida,H., Tsuji,S.

Results of settlement observation are presented for 3 storied reinforced concrete buildings. The buildings are supported on friction group piles in a sand stratum overlying a nearby 40 m thick...

Regulation of STAT3-mediated signaling by LMW-DSP2. (2006)

Sekine, Y., Tsuji, S., Ikeda, O., Sato, N., Aoki, N., Aoyama, K., ...

Signal transducer and activator of transcription 3 (STAT3), which mediates biological actions in many physiological processes, is activated by cytokines and growth factors, and has been reported to...

Regulation of STAT3-mediated signaling by LMW-DSP2. (2006)

Sekine, Y., Tsuji, S., Ikeda, O., Sato, N., Aoki, N., Aoyama, K., ...

Signal transducer and activator of transcription 3 (STAT3), which mediates biological actions in many physiological processes, is activated by cytokines and growth factors, and has been reported to...

Simultaneous determination of creatinine, creatine, and UV-absorbing amino acids using dual-mode gradient low-capacity cation-exchange chromatography (2005)

横山, 幸男, Yokoyama, Yukio, Tsuji, S., Sato, H.

A simple and versatile cation-exchange chromatography technique for the simultaneous determination of urinary creatinine (Cre), creatine (Cm), methionine (Met), tyrosine (Tyr), phenylalanine (Phe),...

Autosomal dominant pure cerebellar ataxia: A clinical and genetic analysis of eight Japanese families (1996)

Ishikawa, K., Mizusawa, H., Saito, M., Tanaka, H., Nakajima, N., Kondo, N., ...

We carried out linkage analysis and clinical assessment on 41 patients with autosomal dominant pure cerebellar ataxia (ADCA) type III from eight Japanese families. The presenting symptom was gait...

Evidence for inter-generational instability in the CAG repeat in the MJD1 gene and for conserved haplotypes at flanking markers amongst Japanese and Caucasian subjects with Machado-Joseph disease (1995)

Takiyama, Y., Igasrashi, S., Rogaeva, E.A., Endo, K., Rogaev, E.I., Tanaka, H., ...

The size of the (CAG)n repeat array in the 3′ end of the MJDI gene and the haplotype at a series of microsateilite markers surrounding the MJD1 gene were examined in a large cohort of Japanese and...

Genetic Similarity Using DNA Fingerprinting in Cattle to Determine Relationship Coefficient (1993)

Mannen, H., Tsuji, S., Mukai, F., Goto, N., Ohtagaki, S.

The relation between relationship coefficient and genetic similarity was evaluated using DNA fingerprinting in Japanese Black cattle. We proposed a new method for evaluating heterozygous and...

Evolutionary relationships of lactate dehydrogenases (LDHs) from mammals, birds, an amphibian, fish, barley, and bacteria: LDH cDNA sequences from Xenopus, pig, and rat.

Tsuji, S, Qureshi, M A, Hou, E W, Fitch, W M, Li, S S

The nucleotide sequences of the cDNAs encoding LDH (EC 1.1.1.27) subunits LDH-A (muscle), LDH-B (liver), and LDH-C (oocyte) from Xenopus laevis, LDH-A (muscle) and LDH-B (heart) from pig, and LDH-B...

Genetic heterogeneity in type 1 Gaucher disease: multiple genotypes in Ashkenazic and non-Ashkenazic individuals.

Tsuji, S, Martin, B M, Barranger, J A, Stubblefield, B K, LaMarca, M E, Ginns, E I

Nucleotide sequence analysis of a genomic clone from an Ashkenazic Jewish patient with type 1 Gaucher disease revealed a single-base mutation (adenosine to guanosine transition) in exon 9 of the...

Gene mapping and leader polypeptide sequence of human glucocerebrosidase: implications for Gaucher disease.

Ginns, E I, Choudary, P V, Tsuji, S, Martin, B, Stubblefield, B, Sawyer, J, ...

Analysis of immunologic cross-reacting material in Chinese hamster-human somatic cell hybrids allowed assignment of the structural gene for glucocerebrosidase (glucosylceramidase;...

An unusual splicing mutation in the HEXB gene is associated with dramatically different phenotypes in patients from different racial backgrounds.

McInnes, B, Potier, M, Wakamatsu, N, Melancon, S B, Klavins, M H, Tsuji, S, ...

Sandhoff disease is caused by mutations affecting the beta subunit of lysosomal beta-hexosaminidase (EC 3.2.1.52) and displays a wide spectrum of clinical phenotypes. We report a 57-year-old patient...

Molecular cloning of human growth inhibitory factor cDNA and its down-regulation in Alzheimer's disease.

Tsuji, S, Kobayashi, H, Uchida, Y, Ihara, Y, Miyatake, T

In previous studies, we discovered a growth inhibitory factor (GIF) that was abundant in normal human brain, but greatly reduced in Alzheimer's disease (AD) brain. Molecular cloning of a full-length...

Ancestral Origins of the Machado-Joseph Disease Mutation: A Worldwide Haplotype Study

Gaspar, C., Lopes-Cendes, I., Hayes, S., Goto, J., Arvidsson, K., Dias, A., ...

Machado-Joseph disease (MJD) is an autosomal dominant neurodegenerative disorder originally described in families of Portuguese-Azorean ancestry. The cloning of the MJD1 gene allowed identification...

Japanese families with autosomal dominant pure cerebellar ataxia map to chromosome 19p13.1-p13.2 and are strongly associated with mild CAG expansions in the spinocerebellar ataxia type 6 gene in chromosome 19p13.1.

Ishikawa, K, Tanaka, H, Saito, M, Ohkoshi, N, Fujita, T, Yoshizawa, K, ...

Autosomal dominant cerebellar ataxia is a group of clinically and genetically heterogeneous disorders. We carried out genomewide linkage analysis in 15 families with autosomal dominant pure...

Close associations between prevalences of dominantly inherited spinocerebellar ataxias with CAG-repeat expansions and frequencies of large normal CAG alleles in Japanese and Caucasian populations.

Takano, H, Cancel, G, Ikeuchi, T, Lorenzetti, D, Mawad, R, Stevanin, G, ...

To test the hypothesis that the frequencies of normal alleles (ANs) with a relatively large number of CAG repeats (large ANs) are related to the prevalences of the dominant spinocerebellar ataxias...

Mitochondrial DNA variation and evolution of Japanese black cattle (Bos taurus).

Mannen, H, Tsuji, S, Loftus, R T, Bradley, D G

This article describes complete mitochondrial DNA displacement loop sequences from 32 Japanese Black cattle and the analysis of these data in conjunction with previously published sequences from...

Identification of a mutation in the arylsulfatase A gene of a patient with adult-type metachromatic leukodystrophy.

Kondo, R, Wakamatsu, N, Yoshino, H, Fukuhara, N, Miyatake, T, Tsuji, S

To analyze the genetic abnormality in a Japanese patient with adult-type metachromatic leukodystrophy (MLD), we first elucidated the genomic organization of the human arylsulfatase A (ASA) gene and...

Evolutionary relationships of lactate dehydrogenases (LDHs) from mammals, birds, an amphibian, fish, barley, and bacteria: LDH cDNA sequences from Xenopus, pig, and rat.

Tsuji, S, Qureshi, M A, Hou, E W, Fitch, W M, Li, S S

The nucleotide sequences of the cDNAs encoding LDH (EC 1.1.1.27) subunits LDH-A (muscle), LDH-B (liver), and LDH-C (oocyte) from Xenopus laevis, LDH-A (muscle) and LDH-B (heart) from pig, and LDH-B...

Genetic heterogeneity in type 1 Gaucher disease: multiple genotypes in Ashkenazic and non-Ashkenazic individuals.

Tsuji, S, Martin, B M, Barranger, J A, Stubblefield, B K, LaMarca, M E, Ginns, E I

Nucleotide sequence analysis of a genomic clone from an Ashkenazic Jewish patient with type 1 Gaucher disease revealed a single-base mutation (adenosine to guanosine transition) in exon 9 of the...

Gene mapping and leader polypeptide sequence of human glucocerebrosidase: implications for Gaucher disease.

Ginns, E I, Choudary, P V, Tsuji, S, Martin, B, Stubblefield, B, Sawyer, J, ...

Analysis of immunologic cross-reacting material in Chinese hamster-human somatic cell hybrids allowed assignment of the structural gene for glucocerebrosidase (glucosylceramidase;...

An unusual splicing mutation in the HEXB gene is associated with dramatically different phenotypes in patients from different racial backgrounds.

McInnes, B, Potier, M, Wakamatsu, N, Melancon, S B, Klavins, M H, Tsuji, S, ...

Sandhoff disease is caused by mutations affecting the beta subunit of lysosomal beta-hexosaminidase (EC 3.2.1.52) and displays a wide spectrum of clinical phenotypes. We report a 57-year-old patient...

Molecular cloning of human growth inhibitory factor cDNA and its down-regulation in Alzheimer's disease.

Tsuji, S, Kobayashi, H, Uchida, Y, Ihara, Y, Miyatake, T

In previous studies, we discovered a growth inhibitory factor (GIF) that was abundant in normal human brain, but greatly reduced in Alzheimer's disease (AD) brain. Molecular cloning of a full-length...

Ancestral Origins of the Machado-Joseph Disease Mutation: A Worldwide Haplotype Study

Gaspar, C., Lopes-Cendes, I., Hayes, S., Goto, J., Arvidsson, K., Dias, A., ...

Machado-Joseph disease (MJD) is an autosomal dominant neurodegenerative disorder originally described in families of Portuguese-Azorean ancestry. The cloning of the MJD1 gene allowed identification...

Close associations between prevalences of dominantly inherited spinocerebellar ataxias with CAG-repeat expansions and frequencies of large normal CAG alleles in Japanese and Caucasian populations.

Takano, H, Cancel, G, Ikeuchi, T, Lorenzetti, D, Mawad, R, Stevanin, G, ...

To test the hypothesis that the frequencies of normal alleles (ANs) with a relatively large number of CAG repeats (large ANs) are related to the prevalences of the dominant spinocerebellar ataxias...

Mitochondrial DNA variation and evolution of Japanese black cattle (Bos taurus).

Mannen, H, Tsuji, S, Loftus, R T, Bradley, D G

This article describes complete mitochondrial DNA displacement loop sequences from 32 Japanese Black cattle and the analysis of these data in conjunction with previously published sequences from...

Identification of a mutation in the arylsulfatase A gene of a patient with adult-type metachromatic leukodystrophy.

Kondo, R, Wakamatsu, N, Yoshino, H, Fukuhara, N, Miyatake, T, Tsuji, S

To analyze the genetic abnormality in a Japanese patient with adult-type metachromatic leukodystrophy (MLD), we first elucidated the genomic organization of the human arylsulfatase A (ASA) gene and...

Localization of a gene for an autosomal recessive form of juvenile Parkinsonism to chromosome 6q25.2-27.

Matsumine, H, Saito, M, Shimoda-Matsubayashi, S, Tanaka, H, Ishikawa, A, Nakagawa-Hattori, Y, ...

An autosomal recessive form of juvenile Parkinsonism (AR-JP) (MIM 600116) is a levodopa-responsive Parkinsonism whose pathological finding is a highly selective degeneration of dopaminergic neurons...

Japanese families with autosomal dominant pure cerebellar ataxia map to chromosome 19p13.1-p13.2 and are strongly associated with mild CAG expansions in the spinocerebellar ataxia type 6 gene in chromosome 19p13.1.

Ishikawa, K, Tanaka, H, Saito, M, Ohkoshi, N, Fujita, T, Yoshizawa, K, ...

Autosomal dominant cerebellar ataxia is a group of clinically and genetically heterogeneous disorders. We carried out genomewide linkage analysis in 15 families with autosomal dominant pure...

Molecular cloning of a full-length cDNA for dentatorubral-pallidoluysian atrophy and regional expressions of the expanded alleles in the CNS.

Onodera, O, Oyake, M, Takano, H, Ikeuchi, T, Igarashi, S, Tsuji, S

Dentatorubral-pallidoluysian atrophy (DRPLA) is an autosomal dominant neurodegenerative disorder characterized by genetic anticipation and variable combinations of symptoms including myoclonus,...

Expression of intercellular adhesion molecule-1 on transitional cell cancer. Possible significance in immunity against tumor cells.

Tomita, Y., Watanabe, H., Kobayashi, H., Nishiyama, T., Tsuji, S., Imai, K., ...

Immunohistochemical examination demonstrated expression of intercellular adhesion molecule-1 (ICAM-1) on 17 of 44 transitional cell cancers (TCCs) but not on normal transitional cells. ICAM-1 was...

Increase in reflex vasoconstriction with indomethacin in patients with orthostatic hypotension and central nervous system involvement.

Imaizumi, T, Takeshita, A, Ashihara, T, Nakamura, M, Tsuji, S, Shibazaki, H

Since indomethacin may be effective in the treatment of orthostatic hypotension, the ability of this drug to increase reflex vasoconstriction was studied in six patients with orthostatic hypotension...

Antibody-independent classical complement pathway activation and homologous C3 deposition in xeroderma pigmentosum cell lines

Kurita, M, Matsumoto, M, Tsuji, S, Kawakami, M, Suzuki, Y, Hayashi, H, ...

Of human malignantly transformed cell lines, xeroderma pigmentosum (XP) cell lines were found to be highly susceptible to homologous complement (C): cells were opsonized by C3 fragments on incubation...

Phenytoin promotes Th2 type immune response in mice

Okada, K, Sugiura, T, Kuroda, E, Tsuji, S, Yamashita, U

The effects of chronic administration of phenytoin, a common anticonvulsive drug, on immune responses were studied in mice. Anti-keyhole limpet haemocyanin (KLH) IgE antibody response after...

Role of reactive oxygen species in neutrophil apoptosis following ingestion of heat-killed Staphylococcus aureus

Yamamoto, A, Taniuchi, S, Tsuji, S, Hasui, M, Kobayashi, Y

Neutrophils, short-lived leucocytes that die by apoptosis, play an important role in the first stage of defense against bacterial infections. It has been reported that phagocytosis of intact bacteria...

Non-Mendelian transmission in dentatorubral-pallidoluysian atrophy and Machado-Joseph disease: the mutant allele is preferentially transmitted in male meiosis.

Ikeuchi, T., Igarashi, S., Takiyama, Y., Onodera, O., Oyake, M., Takano, H., ...

Autosomal dominant dentatorubral-pallidoluysian atrophy (DRPLA) and Machado-Joseph disease (MJD) are neurodegenerative disorders caused by CAG trinucleotide repeat expansions. An inverse correlation...

Somatic mosaicism of expanded CAG repeats in brains of patients with dentatorubral-pallidoluysian atrophy: cellular population-dependent dynamics of mitotic instability.

Takano, H., Onodera, O., Takahashi, H., Igarashi, S., Yamada, M., Oyake, M., ...

Dentatorubral-pallidoluysian atrophy (DRPLA) is an autosomal dominant neurodegenerative disease caused by unstable expansion of a CAG repeat in the DRPLA gene. We performed detailed quantitative...

Cortical deafness in multiple sclerosis

Tabira, T, Tsuji, S, Nagashima, T, Nakajima, T, Kuroiwa, Y

Cortical deafness in a patient with multiple sclerosis is reported. Complete recovery from total deafness was seen following stages of auditory agnosia and pure word deafness. The otological and...

Pure apraxic agraphia with abnormal writing stroke sequences: report of a Japanese patient with a left superior parietal haemorrhage

Otsuki, M., Soma, Y., Arai, T., Otsuka, A., Tsuji, S.

A 67 year old Japanese male patient had pure agraphia after a haemorrhage in the left superior parietal lobule. He developed difficulty in letter formation but showed no linguistic errors, consistent...

Focal (segmental) dyshidrosis in syringomyelia

Sudo, K., Fujiki, N., Tsuji, S., Ajiki, M., Higashi, T., Niino, M., ...

The features or mechanisms of dyshidrosis have not been sufficiently clarified. Neither has the difference between hyperhidrosis and hypohidrosis. To clarify the features and mechanisms of...

Mutations producing premature termination of translation and an amino acid substitution in the sterol 27-hydroxylase gene cause cerebrotendinous xanthomatosis associated with parkinsonism

Wakamatsu, N., Hayashi, M., Kawai, H., Kondo, H., Gotoda, Y., Nishida, Y., ...

OBJECTIVES—Mutational analysis of the sterol 27-hydroxylase (CYP27) gene was performed on three patients from two Japanese families who had cerebrotendinous xanthomatosis (CTX) associated with...

Nocturnal decrease in vasopressin secretion into plasma in patients with multiple system atrophy

Ozawa, T., Tanaka, H., Nakano, R., Sato, M., Inuzuka, T., Soma, Y., ...

To determine whether the nocturnal decrease in arginine vasopressin (AVP) secretion into the plasma, found in a patient with multiple system atrophy (MSA) reported previously, is a usual finding in...