S. V. Faraone

Meta-analysis of 32 genome-wide linkage studies of schizophrenia (2009)

Ng, M Y M, Levinson, D F, Faraone, S V, Suarez, B K, DeLisi, L E, Arinami, T, ...

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ADHD and DAT1: further evidence of paternal over-transmission of risk alleles and haplotype (2009)

Hawi, Z., Kent, L., Hill, M., Anney, R.J.L., Brookes, K.J., Barry, E., ...

We [Hawi et al. (2005); Am J Hum Genet 77:958-965] reported paternal over-transmission of risk alleles in some ADHD-associated genes. This was particularly clear in the case of the DAT1 3-UTR VNTR....

Dopamine and serotonin transporter genotypes moderate sensitivity to maternal expressed emotion: the case of conduct and emotional problems in attention deficit/hyperactivity disorder (2009)

Sonuga-Barke, E., Oades, R.D., Psychogiou, L., Chen, W., Franke, B., Buitelaar, J., ...

Background: Mothers' positive emotions expressed about their children with attention deficit/hyperactivity disorder (ADHD) are associated with a reduced likelihood of comorbid conduct problems (CP)....

Genetic heterogeneity in ADHD: DAT1 gene only affects probands without CD (2008)

Zhou, K., Chen, W., Buitelaar, J., Banaschewski, T., Oades, R.D., Franke, B., ...

Previous studies have found heterogeneous association between DAT1-3-UTR-VNTR and attention deficit hyperactivity disorder (ADHD). Various proportions of conduct disorder (CD) comorbidity in their...

Replication of a rare protective allele in the noradrenaline transporter gene and ADHD (2008)

Xu, X., Hawi, Z., Brookes, K.J., Anney, R., Bellgrove, M., Franke, B., ...

Replication is a key to resolving whether a reported genetic association represents a false positive finding or an actual genetic risk factor. In a previous study screening 51 candidate genes for...

Association of ADHD with genetic variants in the 5'-region of the dopamine transporter gene: evidence for allelic heterogeneity (2008)

Brookes, K.J., Xu, X., Anney, R., Franke, B., Zhou, K., Chen, Wai, ...

Multiple studies have reported an association between attention deficit hyperactivity disorder (ADHD) and the 10-repeat allele of a variable number tandem repeat (VNTR) polymorphism in the...

Linkage to chromosome 1p36 for Attention Deficit Hyperactivity Disorder traits in school and home settings (2008)

Zhou, K., Asherson, P., Sham, P., Franke, B., Anney, R.J., Buitelaar, J., ...

Background Limited success has been achieved through previous attention-deficit/hyperactivity disorder (ADHD) linkage scans, which were all designed to map genes underlying the dichotomous phenotype....

Co-transmission of conduct problems with attention-deficit/hyperactivity disorder: familial evidence for a distinct disorder (2008)

Christiansen, H., Chen, W., Oades, R.D., Asherson, P., Taylor, E.A., Lasky-Su, J., ...

Common disorders of childhood and adolescence are attention-deficit/hyperactivity disorder (ADHD), oppositional defiant disorder (ODD) and conduct disorder (CD). For one to two cases in three...

A high-density SNP linkage scan with 142 combined subtype ADHD sib pairs identifies linkage regions on chromosomes 9 and 16 (2008)

Asherson, P., Zhou, K., Anney, R.J.L., Franke, B., Buitelaar, J., Ebstein, R., ...

As part of the International Multi-centre ADHD Genetics project we completed an affected sibling pair study of 142 narrowly defined Diagnostic and Statistical Manual of Mental Disorders, fourth...

Differential dopamine receptor D4 allele association with ADHD dependent of proband season of birth (2008)

Brookes, K.J., Neale, B., Xu, X., Thapar, A., Gill, M., Langley, K., ...

Season of birth (SOB) has been associated with attention deficit hyperactivity disorder (ADHD) in two existing studies. One further study reported an interaction between SOB and genotypes of the...

Population differences in the international multi-centre ADHD gene project (2008)

Neale, B.M., Sham, P.C., Purcell, S., Banaschewski, T., Buitelaar, J., Franke, B., ...

The International Multi-Centre ADHD Gene sample consists of 674 families from eight countries (Belgium, England, Germany, Holland, Ireland, Israel, Spain, and Switzerland) ascertained from clinics...

DSM-IV combined type ADHD shows familial association with sibling trait scores: A sampling strategy for QTL linkage (2008)

Chen, W., Zhou, K., Sham, P., Franke, B., Kuntsi, J., Campbell, D., ...

Attention deficit hyperactivity disorder (ADHD) is a discrete clinical syndrome characterized by the triad of inattention, hyperactivity, and impulsivity in the context of marked impairments....

No association between two polymorphisms of the serotonin transporter gene and combined type attention deficit hyperactivity disorder (2008)

Xu, X., Aysimi, E., Anney, R., Brookes, K., Franke, B., Zhou, K., ...

Several independent studies have reported association between serotonin transporter gene (SLC6A4) polymorphisms and attention deficit hyperactivity disorder (ADHD). Five studies found evidence for...

Differential dopamine receptor D4 allele association with ADHD dependent of proband season of birth. (2008)

Brookes, K.J., Neale, B., Xu, X., Thapar, A., Gill, M., Langley, K., ...

Season of birth (SOB) has been associated with attention deficit hyperactivity disorder (ADHD) in two existing studies. One further study reported an interaction between SOB and genotypes of the...

Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations (2008)

Lasky-Su, J., Neale, B.M., Franke, B., Anney, R.J.L., Zhou, K., Maller, J.B., ...

Attention deficit hyperactivity disorder (ADHD) is a complex condition with environmental and genetic etiologies. Up to this point, research has identified genetic associations with candidate genes...

Motor coordination problems in children and adolescents with ADHD rated by parents and teachers: effects of age and gender (2007)

Fliers, E., Rommelse, N., Altink, M., Buschgens, C.J.M., Faraone, S.V., ...

Summary. Objective. ADHD is frequently accompanied by motor coordination problems. However, the co-occurrence of poor motor performance has received less attention in research than other coexisting...

Partial replication of a DRD4 association in ADHD individuals using a statistically derived quantitative trait for ADHD in a family-based association test (2007)

Lasky-Su, J., Banaschewski, T., Buitelaar, J., Franke, B., Brookes, K., Sonuga-Barke, E., ...

Background: Lisdexamfetamine dimesylate is a therapeutically inactive prodrug in which d-amphetamine is covalently bound to l-lysine, a naturally occurring amino acid. Pharmacologically active...

Partial replication of a DRD4 association in ADHD individuals using a statistically derived quantitative trait for ADHD in a family-based association test (2007)

Lasky-Su, J., Banaschewski, T., Buitelaar, J., Franke, B., Brookes, K., Sonuga-Barke, E., ...

Background Previous research found an association between single nucleotide polymorphisms (SNPs) in the promoter region of DRD4 and statistically derived phenotypes generated from...

Early onset bipolar disorder: possible linkage to chromosome 9q34 (2006)

Faraone, S V, Lasky-Su, J, Glatt, Stephen J, Eerdewegh, P V, Tsuang, M T

Objectives: Bipolar disorder (BD) is characterized by manic and depressive states that onset at various times in life. Research shows that early onset forms of BD are associated with a stronger...

Latent class analysis shows strong heritability of the Child Behavior Checklist-Juvenile Bipolar Phenotype. (2006)

Althoff, R., Rettew, D.C., Faraone, S.V., Boomsma, D.I., Hudziak, J.J.

The analysis of 51 genes in DSM-IV combined type attention deficit hyperactivity disorder: association signals in DRD4, DAT1 and 16 other genes (2006)

Brookes, K., Xu, X., Chen, W., Zhou, K., Neale, B., Lowe, N., ...

Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder, starting in early childhood and persisting into adulthood in the majority of cases. Family and twin studies...

Five NOTCH4 polymorphisms show weak evidence for association with schizophrenia: evidence from meta-analyses (2005)

Glatt, Stephen J, Wang, R S, Yeh, Y C, Tsuang, M T, Faraone, S V

NOTCH4 initially received consideration as a risk gene for schizophrenia based on its location within a region on chromosome 6p that had previously shown strong evidence for genetic linkage with the...

Prevalence and Genetic Architecture of Child Behavior Checklist-Juvenile Bipolar Disorder (2005)

Hudziak, J.J., Althoff, R.R., Derks, E.M., Faraone, S.V., Boomsma, D.I.

Modest evidence for linkage and possible confirmation of association between NOTCH4 and schizophrenia in a large veterans affairs cooperative study sample (2003)

Skol, A.D., Young, K.A., Tsuang, D.W., Faraone, S.V., Haverstock, S.L., Bingham, S., ...

Wei and Hemmings [2000: Nat Genet 25:376–377], using 80 British parent–offspring trios, identified a number of NOTCH4 variants and haplotypes that showed statistically significant evidence of...