Mitotic inactivation of a human SWI/SNF chromatin remodeling complex (1998)
Sif, Saïd, Stukenberg, P. Todd, Kirschner, Marc W., Kingston, Robert E.
Stable Remodeling of Tailless Nucleosomes by the Human SWI-SNF Complex†
Guyon, Jeffrey R., Narlikar, Geeta J., Sif, Saïd, Kingston, Robert E.
The histone N-terminal tails have been shown previously to be important for chromatin assembly, remodeling, and stability. We have tested the ability of human SWI-SNF (hSWI-SNF) to remodel...
Mammalian SWI-SNF Complexes Contribute to Activation of the hsp70 Gene
De La Serna, Ivana L., Carlson, Kerri A., Hill, David A., Guidi, Cynthia J., Stephenson, Ryan O., Sif, Saïd, ...
ATP-dependent chromatin-remodeling complexes are conserved among all eukaryotes and function by altering nucleosome structure to allow cellular regulatory factors access to the DNA. Mammalian SWI-SNF...
Transcriptional Activation Domains of Human Heat Shock Factor 1 Recruit Human SWI/SNF
Sullivan, E. Kelly, Weirich, Christine S., Guyon, Jeffrey R., Sif, Saïd, Kingston, Robert E.
Chromatin remodeling complexes such as SWI/SNF use the energy of ATP hydrolysis to remodel nucleosomal DNA and increase transcription of nucleosomal templates. Human heat shock factor one (hHSF1) is...
Aoyagi, Sayura, Narlikar, Geeta, Zheng, Chunyang, Sif, Saïd, Kingston, Robert E., Hayes, Jeffrey J.
We utilized a site-specific cross-linking technique to investigate the mechanism of nucleosome remodeling by hSWI/SNF. We found that a single cross-link between H2B and DNA virtually eliminates the...
Pal, Sharmistha, Yun, Romy, Datta, Antara, Lacomis, Lynne, Erdjument-Bromage, Hediye, Kumar, Jitendra, ...
The role of hSWI/SNF complexes in transcriptional activation is well characterized; however, little is known about their function in transcriptional repression. We have previously shown that subunits...
Mitotic inactivation of a human SWI/SNF chromatin remodeling complex
Sif, Saïd, Stukenberg, P. Todd, Kirschner, Marc W., Kingston, Robert E.
During mitosis, chromatin is condensed into mitotic chromosomes and transcription is inhibited, processes that might be opposed by the chromatin remodeling activity of the SWI/SNF complexes. Brg1 and...
Pal, Sharmistha, Vishwanath, Sheethal N., Erdjument-Bromage, Hediye, Tempst, Paul, Sif, Saïd
Protein arginine methyltransferases (PRMTs) have been implicated in transcriptional activation and repression, but their role in controlling cell growth and proliferation remains obscure. We have...
Wang, Li, Baiocchi, Robert A., Pal, Sharmistha, Mosialos, George, Caligiuri, Michael, Sif, Saïd
Mutation of BRG1, hBRM, and their associated factors, INI1 and BAF57, in primary human tumors has suggested that inactivation of human SWI/SNF (hSWI/SNF) complexes may be involved in neoplastic...
Purification and characterization of mSin3A-containing Brg1 and hBrm chromatin remodeling complexes
Sif, Saïd, Saurin, Andrew J., Imbalzano, Anthony N., Kingston, Robert E.
Alteration of nucleosomes by ATP-dependent remodeling complexes represents a critical step in the regulation of transcription. The human SWI/SNF (hSWI/SNF) family is composed of complexes that...
Stable Remodeling of Tailless Nucleosomes by the Human SWI-SNF Complex†
Guyon, Jeffrey R., Narlikar, Geeta J., Sif, Saïd, Kingston, Robert E.
The histone N-terminal tails have been shown previously to be important for chromatin assembly, remodeling, and stability. We have tested the ability of human SWI-SNF (hSWI-SNF) to remodel...
Mammalian SWI-SNF Complexes Contribute to Activation of the hsp70 Gene
De La Serna, Ivana L., Carlson, Kerri A., Hill, David A., Guidi, Cynthia J., Stephenson, Ryan O., Sif, Saïd, ...
ATP-dependent chromatin-remodeling complexes are conserved among all eukaryotes and function by altering nucleosome structure to allow cellular regulatory factors access to the DNA. Mammalian SWI-SNF...
Transcriptional Activation Domains of Human Heat Shock Factor 1 Recruit Human SWI/SNF
Sullivan, E. Kelly, Weirich, Christine S., Guyon, Jeffrey R., Sif, Saïd, Kingston, Robert E.
Chromatin remodeling complexes such as SWI/SNF use the energy of ATP hydrolysis to remodel nucleosomal DNA and increase transcription of nucleosomal templates. Human heat shock factor one (hHSF1) is...
Aoyagi, Sayura, Narlikar, Geeta, Zheng, Chunyang, Sif, Saïd, Kingston, Robert E., Hayes, Jeffrey J.
We utilized a site-specific cross-linking technique to investigate the mechanism of nucleosome remodeling by hSWI/SNF. We found that a single cross-link between H2B and DNA virtually eliminates the...
Pal, Sharmistha, Yun, Romy, Datta, Antara, Lacomis, Lynne, Erdjument-Bromage, Hediye, Kumar, Jitendra, ...
The role of hSWI/SNF complexes in transcriptional activation is well characterized; however, little is known about their function in transcriptional repression. We have previously shown that subunits...
Purification and characterization of mSin3A-containing Brg1 and hBrm chromatin remodeling complexes
Sif, Saïd, Saurin, Andrew J., Imbalzano, Anthony N., Kingston, Robert E.
Alteration of nucleosomes by ATP-dependent remodeling complexes represents a critical step in the regulation of transcription. The human SWI/SNF (hSWI/SNF) family is composed of complexes that...
Mitotic inactivation of a human SWI/SNF chromatin remodeling complex
Sif, Saïd, Stukenberg, P. Todd, Kirschner, Marc W., Kingston, Robert E.
During mitosis, chromatin is condensed into mitotic chromosomes and transcription is inhibited, processes that might be opposed by the chromatin remodeling activity of the SWI/SNF complexes. Brg1 and...
Pal, Sharmistha, Vishwanath, Sheethal N., Erdjument-Bromage, Hediye, Tempst, Paul, Sif, Saïd
Protein arginine methyltransferases (PRMTs) have been implicated in transcriptional activation and repression, but their role in controlling cell growth and proliferation remains obscure. We have...
Wang, Li, Baiocchi, Robert A., Pal, Sharmistha, Mosialos, George, Caligiuri, Michael, Sif, Saïd
Mutation of BRG1, hBRM, and their associated factors, INI1 and BAF57, in primary human tumors has suggested that inactivation of human SWI/SNF (hSWI/SNF) complexes may be involved in neoplastic...
Dacwag, Caroline S., Ohkawa, Yasuyuki, Pal, Sharmistha, Sif, Saïd, Imbalzano, Anthony N.
Skeletal muscle differentiation requires the coordinated activity of transcription factors, histone modifying enzymes, and ATP-dependent chromatin remodeling enzymes. The type II protein arginine...
Low levels of miR-92b/96 induce PRMT5 translation and H3R8/H4R3 methylation in mantle cell lymphoma
Pal, Sharmistha, Baiocchi, Robert A, Byrd, John C, Grever, Michael R, Jacob, Samson T, Sif, Saïd
Protein arginine methyltransferase PRMT5 interacts with human SWI/SNF complexes and methylates histones H3R8 and H4R3. To elucidate the role of PRMT5 in human cancer, we analyzed PRMT5 expression in...
Wang, Li, Pal, Sharmistha, Sif, Saïd
The proper epigenetic modification of chromatin by protein arginine methyltransferases (PRMTs) is crucial for normal cell growth and health. The human SWI/SNF-associated PRMT5 is involved in the...
Dacwag, Caroline S., Bedford, Mark T., Sif, Saïd, Imbalzano, Anthony N.
Temporal regulation of gene expression is a hallmark of cellular differentiation pathways, yet the mechanisms controlling the timing of expression for different classes of differentiation-specific...