Sabine Elowe

Tension-sensitive Plk1 phosphorylation on BubR1 regulates the stability of kinetochore microtubule interactions (2007)

Elowe, Sabine, Hümmer, Stefan, Uldschmid, Andreas, Li, Xiuling, Nigg, Erich A.

Mitotic phosphorylation of the spindle checkpoint component BubR1 is highly conserved throughout evolution. Here, we demonstrate that BubR1 is phosphorylated on the Cdk1 site T620, which triggers the...

Minimal catalytic domain of N-acetylglucosaminyltransferase V (2000)

Korczak, Bozena, Le, Thuyanh, Elowe, Sabine, Datti, Alessandro, Dennis, James W.

UDP-GlcNAc: Manα1–6Man&bgr;-R &bgr;1–6 N-acetylglucosaminyltransferase V (EC 2.4.1.155, GlcNAc-TV) is a Golgi enzyme that substitutes the trimannosyl core in the biosynthetic pathway for...

Downregulation of the Ras–Mitogen-Activated Protein Kinase Pathway by the EphB2 Receptor Tyrosine Kinase Is Required for Ephrin-Induced Neurite Retraction

Elowe, Sabine, Holland, Sacha J., Kulkarni, Sarang, Pawson, Tony

Activation of the EphB2 receptor tyrosine kinase by clustered ephrin-B1 induces growth cone collapse and neurite retraction in differentiated NG108 neuronal cells. We have investigated the...

Downregulation of the Ras–Mitogen-Activated Protein Kinase Pathway by the EphB2 Receptor Tyrosine Kinase Is Required for Ephrin-Induced Neurite Retraction

Elowe, Sabine, Holland, Sacha J., Kulkarni, Sarang, Pawson, Tony

Activation of the EphB2 receptor tyrosine kinase by clustered ephrin-B1 induces growth cone collapse and neurite retraction in differentiated NG108 neuronal cells. We have investigated the...

Tension-sensitive Plk1 phosphorylation on BubR1 regulates the stability of kinetochore–microtubule interactions

Elowe, Sabine, Hümmer, Stefan, Uldschmid, Andreas, Li, Xiuling, Nigg, Erich A.

Mitotic phosphorylation of the spindle checkpoint component BubR1 is highly conserved throughout evolution. Here, we demonstrate that BubR1 is phosphorylated on the Cdk1 site T620, which triggers the...