Sakan Maeda

Osteoblast Differentiation and Bone Formation Gene Expression in Strontium-inducing Bone Marrow Mesenchymal Stem Cell (2007)

SILA-ASNA, MONNIPHA, BUNYARATVEJ, AHNOND, Maeda, Sakan, Kitaguchi, Hiromichi, BUNYARATAVEJ, NARONG

Osteoblastic differentiation from human mesenchymal stem cell (hMSCs) is animportant step of bone formation. We studied the in vitro induction of hMSCs byusing strontium ranelate, a natural trace...

PKC Pathway and ERK/MAPK Pathway Are Required for Induction of Cyclin D1 and p21Waf1 during 12-o-tetradecanoylphorbol 13-acetate-induced Differentiation of Myeloleukemia Cells (2006)

Matsumoto, Eriko, Hatanaka, Michiyo, Bohgaki, Miyako, Maeda, Sakan

Treatment of human promyelocytic leukemia cell HL60 with12-o-tetradecanoylphorbol 13-acetate (TPA) induces growth arrest, differentiationtowards the monocyte/macrophage lineage, and expression of...

Prevention of autoimmune insulin-dependent diabetes in non-obese diabetic mice by anti-LFA-1 and anti-ICAM-1 mAb (1994)

Hasegawa, Yutaka, Yokono, Koichl, Taki, Toshiya, Amano, Kazuhiko, Tominaga, Yolchi, Yoneda, Ryoji, ...

Diverse adhesion molecules participate in many important responses and thus would be implicated in the pathogenesis of various autoimmune diseases. However, there is little evidence for the role of...

The Asparagine-Linked Sugar Chains of Plasma Membrane Glycoproteins of K-562 Human Leukaemic Cells: A Comparative Study with Human Erythrocytes (1982)

YOSHIMA, Hideo, SHIRAISHI, Nobuyuki, MATSUMOTO, Akira, MAEDA, Sakan, SUGIYAMA, Taketoshi, KOBATA, Akira

The paper electrophoretic pattern of the oligosaccharides released from the plasma membranes of K-562 cells by hydrazinolysis was quite different from that of human erythrocyte membranes. Bio-Gel P-4...

A role for heterologous gap junctions between melanoma and endothelial cells in metastasis

Ito, Akihiko, Katoh, Fumitaka, Kataoka, Tatsuki R., Okada, Morihito, Tsubota, Noriaki, Asada, Hideo, ...

F10 and BL6 sublines of B16 mouse melanoma cells are metastatic after intravenous injection, but only BL6 cells are metastatic after subcutaneous injection. We found that connexin (Cx) 26 is...

PKCλ regulates glucose-induced insulin secretion through modulation of gene expression in pancreatic β cells

Hashimoto, Naoko, Kido, Yoshiaki, Uchida, Tohru, Matsuda, Tomokazu, Suzuki, Kazuhisa, Inoue, Hiroshi, ...

Altered regulation of insulin secretion by glucose is characteristic of individuals with type 2 diabetes mellitus, although the mechanisms that underlie this change remain unclear. We have now...

Congenital Semilunar Valvulogenesis Defect in Mice Deficient in Phospholipase Cɛ†

Tadano, Makoto, Edamatsu, Hironori, Minamisawa, Susumu, Yokoyama, Utako, Ishikawa, Yoshihiro, Suzuki, Noboru, ...

Phospholipase Cɛ is a novel class of phosphoinositide-specific phospholipase C, identified as a downstream effector of Ras and Rap small GTPases. We report here the first genetic analysis of its...

MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity

Kanda, Hajime, Tateya, Sanshiro, Tamori, Yoshikazu, Kotani, Ko, Hiasa, Ken-ichi, Kitazawa, Riko, ...

Adipocytes secrete a variety of bioactive molecules that affect the insulin sensitivity of other tissues. We now show that the abundance of monocyte chemoattractant protein–1 (MCP-1) mRNA in...

A role for heterologous gap junctions between melanoma and endothelial cells in metastasis

Ito, Akihiko, Katoh, Fumitaka, Kataoka, Tatsuki R., Okada, Morihito, Tsubota, Noriaki, Asada, Hideo, ...

F10 and BL6 sublines of B16 mouse melanoma cells are metastatic after intravenous injection, but only BL6 cells are metastatic after subcutaneous injection. We found that connexin (Cx) 26 is...

PKCλ regulates glucose-induced insulin secretion through modulation of gene expression in pancreatic β cells

Hashimoto, Naoko, Kido, Yoshiaki, Uchida, Tohru, Matsuda, Tomokazu, Suzuki, Kazuhisa, Inoue, Hiroshi, ...

Altered regulation of insulin secretion by glucose is characteristic of individuals with type 2 diabetes mellitus, although the mechanisms that underlie this change remain unclear. We have now...

Congenital Semilunar Valvulogenesis Defect in Mice Deficient in Phospholipase Cɛ†

Tadano, Makoto, Edamatsu, Hironori, Minamisawa, Susumu, Yokoyama, Utako, Ishikawa, Yoshihiro, Suzuki, Noboru, ...

Phospholipase Cɛ is a novel class of phosphoinositide-specific phospholipase C, identified as a downstream effector of Ras and Rap small GTPases. We report here the first genetic analysis of its...

MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity

Kanda, Hajime, Tateya, Sanshiro, Tamori, Yoshikazu, Kotani, Ko, Hiasa, Ken-ichi, Kitazawa, Riko, ...

Adipocytes secrete a variety of bioactive molecules that affect the insulin sensitivity of other tissues. We now show that the abundance of monocyte chemoattractant protein–1 (MCP-1) mRNA in...