Sally C. Kent

Multiple differences in gene expression in regulatory Vα24JαQ T cells from identical twins discordant for type I diabetes

Wilson, S. Brian, Kent, Sally C., Horton, Heidi F., Hill, Andrew A., Bollyky, Paul L., Hafler, David A., ...

Quantitative and qualitative defects in CD1d-restricted T cells have been demonstrated in human and murine autoimmune diseases. To investigate the transcriptional consequences of T cell receptor...

Heterophile antibodies segregate in families and are associated with protection from type 1 diabetes

She, Jin-Xiong, Ellis, Tamir M., Wilson, S. Brian, Wasserfall, Clive H., Marron, Michele, Reimsneider, Sharon, ...

Markedly elevated levels of serum IL-4 were reported previously in 50% of a small group of type 1 diabetes nonprogessors. To determine the patterns of expression for this phenotype, a larger cohort...

GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes

Viglietta, Vissia, Kent, Sally C., Orban, Tihamer, Hafler, David A.

Insulin-dependent type 1 diabetes is an autoimmune disease mediated by T lymphocytes recognizing pancreatic islet cell antigens. Glutamic acid decarboxylase 65 (GAD65) appears to be an important...

HIV-1 fusion peptide targets the TCR and inhibits antigen-specific T cell activation

Quintana, Francisco J., Gerber, Doron, Kent, Sally C., Cohen, Irun R., Shai, Yechiel

The fusion peptide (FP) in the N terminus of the HIV envelope glycoprotein, gp41, functions together with other gp41 domains to fuse the virion with the host cell membrane. We now report that FP...

Multiple differences in gene expression in regulatory Vα24JαQ T cells from identical twins discordant for type I diabetes

Wilson, S. Brian, Kent, Sally C., Horton, Heidi F., Hill, Andrew A., Bollyky, Paul L., Hafler, David A., ...

Quantitative and qualitative defects in CD1d-restricted T cells have been demonstrated in human and murine autoimmune diseases. To investigate the transcriptional consequences of T cell receptor...

Heterophile antibodies segregate in families and are associated with protection from type 1 diabetes

She, Jin-Xiong, Ellis, Tamir M., Wilson, S. Brian, Wasserfall, Clive H., Marron, Michele, Reimsneider, Sharon, ...

Markedly elevated levels of serum IL-4 were reported previously in 50% of a small group of type 1 diabetes nonprogessors. To determine the patterns of expression for this phenotype, a larger cohort...

GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes

Viglietta, Vissia, Kent, Sally C., Orban, Tihamer, Hafler, David A.

Insulin-dependent type 1 diabetes is an autoimmune disease mediated by T lymphocytes recognizing pancreatic islet cell antigens. Glutamic acid decarboxylase 65 (GAD65) appears to be an important...

HIV-1 fusion peptide targets the TCR and inhibits antigen-specific T cell activation

Quintana, Francisco J., Gerber, Doron, Kent, Sally C., Cohen, Irun R., Shai, Yechiel

The fusion peptide (FP) in the N terminus of the HIV envelope glycoprotein, gp41, functions together with other gp41 domains to fuse the virion with the host cell membrane. We now report that FP...

Evasion of peptide, but not lipid antigen presentation, through pathogen-induced dendritic cell maturation

Hava, David L., Van Der Wel, Nicole, Cohen, Nadia, Dascher, Christopher C., Houben, Diane, León, Luis, ...

Dendritic cells (DC) present lipid and peptide antigens to T cells on CD1 and MHC Class II (MHCII), respectively. The relative contribution of these systems during the initiation of adaptive immunity...