Hiroyuki Nakai, Xiaolin Wu, Sally Fuess, Theresa A. Storm, David Munroe, Eugenio Montini, ...
Recombinant adeno-associated virus (rAAV) vector holds promise for gene therapy. Despite a low frequency of chromosomal integration of vector genomes, recent studies have raised concerns about the...
BAR: An apoptosis regulator at the intersection of caspases and Bcl-2 family proteins
Zhang, Hong, Xu, Qunli, Krajewski, Stanislaw, Krajewska, Maryla, Xie, Zhihua, Fuess, Sally, ...
Two major pathways for induction of apoptosis have been identified—intrinsic and extrinsic. The extrinsic pathway is represented by tumor necrosis factor family receptors, which utilize protein...
Nakai, Hiroyuki, Yant, Stephen R., Storm, Theresa A., Fuess, Sally, Meuse, Leonard, Kay, Mark A.
Recombinant adeno-associated virus (rAAV) vectors stably transduce hepatocytes in experimental animals. Although the vector genomes are found both as extrachromosomes and as chromosomally integrated...
Nakai, Hiroyuki, Thomas, Clare E., Storm, Theresa A., Fuess, Sally, Powell, Sharon, Wright, J. Fraser, ...
Recombinant adeno-associated virus (rAAV) vectors are promising vehicles for achieving stable liver transduction in vivo. However, the mechanisms of liver transduction are not fully understood, and...
Unrestricted Hepatocyte Transduction with Adeno-Associated Virus Serotype 8 Vectors in Mice
Nakai, Hiroyuki, Fuess, Sally, Storm, Theresa A., Muramatsu, Shin-ichi, Nara, Yuko, Kay, Mark A.
Recombinant adeno-associated virus (rAAV) vectors can mediate long-term stable transduction in various target tissues. However, with rAAV serotype 2 (rAAV2) vectors, liver transduction is confined to...
Large-Scale Molecular Characterization of Adeno-Associated Virus Vector Integration in Mouse Liver
Nakai, Hiroyuki, Wu, Xiaolin, Fuess, Sally, Storm, Theresa A., Munroe, David, Montini, Eugenio, ...
Recombinant adeno-associated virus (rAAV) vector holds promise for gene therapy. Despite a low frequency of chromosomal integration of vector genomes, recent studies have raised concerns about the...
BAR: An apoptosis regulator at the intersection of caspases and Bcl-2 family proteins
Zhang, Hong, Xu, Qunli, Krajewski, Stanislaw, Krajewska, Maryla, Xie, Zhihua, Fuess, Sally, ...
Two major pathways for induction of apoptosis have been identified—intrinsic and extrinsic. The extrinsic pathway is represented by tumor necrosis factor family receptors, which utilize protein...
Nakai, Hiroyuki, Yant, Stephen R., Storm, Theresa A., Fuess, Sally, Meuse, Leonard, Kay, Mark A.
Recombinant adeno-associated virus (rAAV) vectors stably transduce hepatocytes in experimental animals. Although the vector genomes are found both as extrachromosomes and as chromosomally integrated...
Nakai, Hiroyuki, Thomas, Clare E., Storm, Theresa A., Fuess, Sally, Powell, Sharon, Wright, J. Fraser, ...
Recombinant adeno-associated virus (rAAV) vectors are promising vehicles for achieving stable liver transduction in vivo. However, the mechanisms of liver transduction are not fully understood, and...
Unrestricted Hepatocyte Transduction with Adeno-Associated Virus Serotype 8 Vectors in Mice
Nakai, Hiroyuki, Fuess, Sally, Storm, Theresa A., Muramatsu, Shin-ichi, Nara, Yuko, Kay, Mark A.
Recombinant adeno-associated virus (rAAV) vectors can mediate long-term stable transduction in various target tissues. However, with rAAV serotype 2 (rAAV2) vectors, liver transduction is confined to...
Large-Scale Molecular Characterization of Adeno-Associated Virus Vector Integration in Mouse Liver
Nakai, Hiroyuki, Wu, Xiaolin, Fuess, Sally, Storm, Theresa A., Munroe, David, Montini, Eugenio, ...
Recombinant adeno-associated virus (rAAV) vector holds promise for gene therapy. Despite a low frequency of chromosomal integration of vector genomes, recent studies have raised concerns about the...
Inagaki, Katsuya, Lewis, Susanna M., Wu, Xiaolin, Ma, Congrong, Munroe, David J., Fuess, Sally, ...
Our previous study has shown that recombinant adeno-associated virus (rAAV) vector integrates preferentially in genes, near transcription start sites and CpG islands in mouse liver (H. Nakai, X. Wu,...