Samar Basu

Oxidative stress and bone mineral density in elderly men : antioxidant activity of alpha-tocopherol (2009)

Östman, Bengt, Michaëlsson, Karl, Helmersson, Johanna, Byberg, Liisa, Gedeborg, Rolf, Melhus, Håkan, ...

Oxidative stress has recently been identified as a pivotal pathogenetic factor of bone loss in mice, but its importance in humans is not clear. We aimed to investigate the association between urinary...

Insulin sensitivity measured with euglycemic clamp is independently associated with glomerular filtration rate in a community-based cohort (2008)

Nerpin, Elisabet, Risérus, Ulf, Ingelsson, Erik, Sundström, Johan, Jobs, Magnus, Larsson, Anders, ...

Objective: To investigate the association between insulin sensitivity and glomerular filtration rate (GFR) in the community, with pre-specified subgroup analyses in normoglycemic individuals with...

Microalbuminuria Measured by three Different Methods, Blood Pressure and Cardiovascular Risk Factors in Elderly Swedish Males (2008)

Gösta Florvall, Samar Basu, Johanna Helmersson, Anders Larsson

Microalbuminuria is associated with hypertension and is a strong risk factor for subsequent chronic disease, both renal and coronary heart disease (CHD), Presently there are several methods available...

Low-grade albuminuria and the incidence of heart failure in a community-based cohort of elderly men (2007)

Ingelsson, Erik, Sundström, Johan, Lind, Lars, Risérus, Ulf, Larsson, Anders, Basu, Samar, ...

Aims To investigate associations of urinary albumin excretion rate (UAER) and heart failure (HF) incidence in a community-based sample. Methods and results In a prospective study of 70-year-old men...

Increased isoprostane and prostaglandin are prominent in neurons in Alzheimer disease (2007)

Casadesus, Gemma, Smith, Mark A, Basu, Samar, Hua, Jing, Capobianco, Dae E, Siedlak, Sandra L, ...

Abstract Background Inflammation and oxidative stress are both involved in the pathogenesis of Alzheimer disease and have been shown to be reciprocally linked. One group of molecules that have been...

Increased isoprostane and prostaglandin are prominent in neurons in Alzheimer disease. (2007)

Casadesus, Gemma, Smith, Mark A, Basu, Samar, Hua, Jing, Capobianco, Dae E, Siedlak, Sandra L, ...

BACKGROUND: Inflammation and oxidative stress are both involved in the pathogenesis of Alzheimer disease and have been shown to be reciprocally linked. One group of molecules that have been directly...

Cardio-cerebral and metabolic effects of methylene blue in hypertonic sodium lactate during experimental cardiopulmonary resuscitation (2007)

Miclescu, Adriana, Basu, Samar, Wiklund, Lars

BACKGROUND: Methylene blue (MB) administered with a hypertonic-hyperoncotic solution reduces the myocardial and cerebral damage due to ischaemia and reperfusion injury after experimental cardiac...

Ropivacaine May Have Advantages Compared to Bupivacaine in Porcine Endotoxemic Shock (2006)

Mutschler, Diana K., Gustafsson, Urban, Basu, Samar, Larsson, Anders O., Eriksson, Mats B.

Patients that undergo major abdominal surgery often receive epidural postoperative analgesia. Septic complications are frequently seen in this cohort. In a porcine model of endotoxemic shock,...

Methylene blue added to a hypertonic-hyperoncotic solution increases short-term survival in experimental cardiac arrest (2006)

Miclescu, Adriana, Basu, Samar, Wiklund, Lars

OBJECTIVE: Methylene blue (MB), a free-radical scavenger inhibiting the production and actions of nitric oxide, may counteract excessive vasodilatation induced by nitric oxide during cardiac arrest....

N-acetylcysteine attenuates kidney injury in rats subjected to renal ischaemia-reperfusion (2006)

Nitescu, Nicoletta, Ricksten, Sven-Erik, Marcussen, Niels, Haraldsson, Börje, Nilsson, Ulf, Basu, Samar, ...

Background. The aim of the present study is to examine the effects of N-acetylcysteine (NAC), a thiol-containing anti-oxidant, on renal function and morphology, and biomarkers of oxidative stress, in...

N-acetylcysteine attenuates kidney injury in rats subjected to renal ischaemia-reperfusion (2006)

Nitescu, Nicoletta, Ricksten, Sven-Erik, Marcussen, Niels, Haraldsson, Börje, Nilsson, Ulf, Basu, Samar, ...

Background. The aim of the present study is to examine the effects of N-acetylcysteine (NAC), a thiol-containing anti-oxidant, on renal function and morphology, and biomarkers of oxidative stress, in...

N-acetylcysteine attenuates kidney injury in rats subjected to renal ischaemia-reperfusion (2006)

Nitescu, Nicoletta, Ricksten, Sven-Erik, Marcussen, Niels, Haraldsson, Borje, Nilsson, Ulf, Basu, Samar, ...

Background. The aim of the present study is to examine the effects of N-acetylcysteine (NAC), a thiol-containing anti-oxidant, on renal function and morphology, and biomarkers of oxidative stress, in...

N-acetylcysteine attenuates kidney injury in rats subjected to renal ischaemia-reperfusion (2006)

Nitescu, Nicoletta, Ricksten, Sven-Erik, Marcussen, Niels, Haraldsson, Börje, Nilsson, Ulf, Basu, Samar, ...

Background. The aim of the present study is to examine the effects of N-acetylcysteine (NAC), a thiol-containing anti-oxidant, on renal function and morphology, and biomarkers of oxidative stress, in...

Microalbuminuria, blood pressure and cardiovascular risk factors in elderly males (2005)

Florvall, Gösta, Basu, Samar, Helmersson, Johanna, Larsson, Anders

Objective - To correlate blood pressure and inflammatory markers with urine albumin analysed with a point-of-care testing (POCT) instrument, nephelometric determination of albumin and creatinine...

Microalbuminuria, blood pressure and cardiovascular risk factors in elderly males (2005)

Florvall, Gösta, Basu, Samar, Helmersson, Johanna, Larsson, Anders

Objective - To correlate blood pressure and inflammatory markers with urine albumin analysed with a point-of-care testing (POCT) instrument, nephelometric determination of albumin and creatinine...

Evidence for Time-dependent Maximum Increase ofFree Radical Damage and Eicosanoid Formation in theBrain as Related to Duration of Cardiac Arrest andCardio-pulmonary Resuscitation (2003)

Basu, Samar, Liu, Xiaoli, Nozari, Ala, Rubertsson, Sten, Miclescu, Adriana, Wiklund, Lars

Recovery of neurological function in patients following cardiac arrest and cardiopulmonary resuscitation (CPR) is a complex event. Free radical induced oxidative stress is supposed to be involved in...

High Energy-Density Electrodes for Alkali-Metal Battery Systems. (2002)

Worrell,Wayne L., Basu,Samar, Nagelberg,Alan

One major impediment in the development of new alkali-metal battery systems with high energy density is the lack of suitable electrode materials. Dichalcogenides of the Group IV and V transition...

Supplementation with vitamins C and E inhibits the release of interleukin-6 from contracting human skeletal muscle

Fischer, Christian P, Hiscock, Natalie J, Penkowa, Milena, Basu, Samar, Vessby, Bengt, Kallner, Anders, ...

Contracting human skeletal muscle is a major contributor to the exercise-induced increase of plasma interleukin-6 (IL-6). Although antioxidants have been shown to attenuate the exercise-induced...

Supplementation with vitamins C and E inhibits the release of interleukin-6 from contracting human skeletal muscle

Fischer, Christian P, Hiscock, Natalie J, Penkowa, Milena, Basu, Samar, Vessby, Bengt, Kallner, Anders, ...

Contracting human skeletal muscle is a major contributor to the exercise-induced increase of plasma interleukin-6 (IL-6). Although antioxidants have been shown to attenuate the exercise-induced...

The enigma of in vivo oxidative stress assessment: isoprostanes as an emerging target

Basu, Samar

Oxidative stress is believed to be one of the major factors behind several acute and chronic diseases, and may also be associated with ageing. Excess formation of free radicals in miscellaneous body...

Microalbuminuria Measured by three Different Methods, Blood Pressure and Cardiovascular Risk Factors in Elderly Swedish Males

Florvall, Gösta, Basu, Samar, Helmersson, Johanna, Larsson, Anders

Microalbuminuria is associated with hypertension and is a strong risk factor for subsequent chronic disease, both renal and coronary heart disease (CHD), Presently there are several methods available...

Insulin Sensitivity Measured With Euglycemic Clamp Is Independently Associated With Glomerular Filtration Rate in a Community-Based Cohort

Nerpin, Elisabet, Risérus, Ulf, Ingelsson, Erik, Sundström, Johan, Jobs, Magnus, Larsson, Anders, ...

OBJECTIVE—To investigate the association between insulin sensitivity and glomerular filtration rate (GFR) in the community, with prespecified subgroup analyses in normoglycemic individuals with...