Alharbi, Khalid K., Spanakis, Emmanuel, Tan, Karen, Smith, Matt J., Aldahmesh, Mohammed A., O'Dell, Sandra D., ...
Identification of unknown mutations has remained laborious, expensive, and only viable for studies of selected cases. Population-based "reference ranges" of rarer sequence diversity are not...
Haplotypic analyses of the IGF2-INS-TH gene cluster in relation to cardiovascular risk traits (2004)
Rodríguez, Santiago, Gaunt, Tom R., O'Dell, Sandra D., Chen, Xiao-he, Gu, Dongfeng, Hawe, Emma, ...
The IGF2-INS-TH genomic region has been implicated in various common disorders including the metabolic syndrome, type 2 diabetes and coronary heart disease (CHD). Here we present detailed haplotype...
Haplotypic analyses of the IGF2-INS-TH gene cluster in relation to cardiovascular risk traits (2004)
Rodríguez, Santiago, Gaunt, Tom R., O'Dell, Sandra D., Chen, Xiao-he, Gu, Dongfeng, Hawe, Emma, ...
The IGF2–INS–TH genomic region has been implicated in various common disorders including the metabolic syndrome, type 2 diabetes and coronary heart disease (CHD). Here we present detailed...
Haplotypic analyses of the IGF2-INS-TH gene cluster in relation to cardiovascular risk traits (2004)
Rodríguez, Santiago, Gaunt, Tom R., O'Dell, Sandra D., Chen, Xiao-he, Gu, Dongfeng, Hawe, Emma, ...
The IGF2-INS-TH genomic region has been implicated in various common disorders including the metabolic syndrome, type 2 diabetes and coronary heart disease (CHD). Here we present detailed haplotype...
Polymorphism of the IGF2 gene, birth weight and grip strength in adult men (2002)
Sayer, Avan Aihie, Syddall, Holly, O'Dell, Sandra D., Chen, Xiao-he, Briggs, Patricia J., Briggs, R., ...
BACKGROUND: Grip strength is a simple measure of skeletal muscle function but a powerful predictor of disability, morbidity and mortality. Recent evidence has shown that prenatal and infant growth...
Microplate array diagonal gel electrophoresis for cohort studies of microsatellite loci (2002)
Chen, Xiao-He, O'Dell, Sandra D., Day, Ian N.M.
After PCR amplification, we have achieved precise sizing of trinucleotide and tetranucleotide microsatellite alleles on 96-well open-faced polyacrylamide microplate array diagonal gel electrophoresis...
Gu, Dongfeng, O'Dell, Sandra D., Chen, Xiao-he, Miller, George J., Day, Ian N.
Abstract. The subtelomeric region of 11p harbours three closely linked genes, TH, INS and IGF2, that have been associated with obesity, size at birth, type I diabetes, polycystic ovary syndrome,...
O'Dell, Sandra D., Syddall, Holly E., Sayer, Avan Aihie, Cooper, Cyrus, Fall, Caroline H.D., Dennison, Elaine M., ...
Ciliary neurotrophic factor (CNTF) administration reduces weight in leptin-resistant mice via the signalling pathway normally activated by leptin. A G>A null mutation in the CNTF gene results in...
Polymorphism of the IGF2 gene, birth weight and grip strength in adult men (2002)
Aihie-Sayer, Avan, Syddall, Holly, O'Dell, Sandra D., Chen, Xiao-He, Briggs, Patricia J., Briggs, R., ...
BACKGROUND: Grip strength is a simple measure of skeletal muscle function but a powerful predictor of disability, morbidity and mortality. Recent evidence has shown that prenatal and infant growth...
Polymorphism of the IGF2 gene, birth weight and grip strength in adult men (2002)
Sayer, Avan Aihie, Syddall, Holly, O'Dell, Sandra D., Chen, Xiao-he, Briggs, Patricia J., Briggs, R., ...
Background: grip strength is a simple measure of skeletal muscle function but a powerful predictor of disability, morbidity and mortality. Recent evidence has shown that prenatal and infant growth...
Gaunt, Tom R., Cooper, Jacqueline A., Miller, George J., Day, Ian N.M., O'Dell, Sandra D.
We previously demonstrated an association between the insulin-like growth factor 2 (IGF2) gene 3'-untranslated region (3'-UTR) ApaI polymorphism and body mass index (BMI) in over 2500 middle-aged...