Sanford Berman

Diagnostic Antigens and Antisera in Tablet Form

Berman, Sanford, Vincent, Gary, Altieri, Patricia L., Lowenthal, Joseph P.

Diagnostic antigen suspensions and antisera can be prepared in tablet form with no loss in potency.

FACTORS AFFECTING THE ELABORATION BY CLOSTRIDIUM HISTOLYTICUM OF PROTEINASES CAPABLE OF DEBRIDING THIRD DEGREE BURN ESCHARS ON GUINEA PIGS

Berman, Sanford, Lowenthal, Joseph P., Webster, Marion E., Altieri, Patricia L., Gochenour, Raymond B.

Berman, Sanford (Walter Reed Army Institute of Research, Washington, D. C.), Joseph P. Lowenthal, Marion E. Webster, Patricia L. Altieri, and Raymond B. Gochenour. Factors affecting the elaboration...

LARGE SCALE PURIFICATION OF PROTEINASES FROM CLOSTRIDIUM HISTOLYTICUM FILTRATES

Conklin, David A., Webster, Marion E., Altieri, Patricia L., Berman, Sanford, Lowenthal, Joseph P., Gochenour, Raymond B.

Conklin, David A. (Walter Reed Army Institute of Research, Washington, D. C.), Marion E. Webster, Patricia L. Altieri, Sanford Berman, Joseph P. Lowenthal, and Raymond B. Gochenour. Large scale...

ENZYMATIC DEBRIDEMENT OF THIRD-DEGREE BURNS ON GUINEA PIGS BY CLOSTRIDIUM HISTOLYTICUM PROTEINASES

Webster, Marion E., Altieri, Patricia L., Conklin, David A., Berman, Sanford, Lowenthal, Joseph P., Gochenour, Raymond B.

Webster, Marion E. (Walter Reed Army Institute of Research, Washington, D. C.), Patricia L. Altieri, David A. Conklin, Sanford Berman, Joseph P. Lowenthal, and Raymond B. Gochenour. Enzymatic...

Mouse Potency Assay for Western Equine Encephalomyelitis Vaccines

Robinson, David M., Berman, Sanford, Lowenthal, Joseph P.

A potency assay for Western equine encephalomyelitis vaccine was developed which utilized mice as the test animal instead of guinea pigs or hamsters. By immunizing several groups of mice with...

Stable Reagent for the Detection of Antibody to the Specific Fraction I Antigen of Yersinia pestis1

Rust, James H., Berman, Sanford, Habig, William H., Marshall, John D., Cavanaugh, Dan C.

A stable hemagglutinating antigen for detection of fraction I (FR-I) antibody of Yersinia pestis (Pasteurella pestis) is described. The antigen was prepared by sensitizing tanned,...

Preparation of Purified Suspensions of Coxiella burneti by Genetron Extraction Followed by Continuous-Flow Ultracentrifugation1

Dubois, Doria R., Cutchins, Ernest C., Berman, Sanford, Lowenthal, Joseph P., Timchak, Robert L.

A method for the preparation of purified suspensions of Coxiella burneti by Genetron extraction followed by continuous-flow density gradient ultracentrifugation is described. Both phases of the...

Comparative Immunogenicities of Chikungunya Vaccines Propagated in Monkey Kidney Monolayers and Chick Embryo Suspension Cultures

White, Arthur, Berman, Sanford, Lowenthal, Joseph P.

A comparative study was made of Formalin-inactivated Chikungunya vaccines prepared from the virus propagated in African green monkey kidney monolayers and concentrated chick embryo suspension...

Preparation of Cholera Vaccines by Fluorocarbon Extraction of Cholera Vibrio Suspensions

Altieri, Patricia L., Berman, Sanford, Groffinger, Albert, Lowenthal, Joseph P.

Experimental cholera vaccines were prepared from suspensions of cholera vibrios which were extracted with Genetron-113. These vaccines, when compared with a control preparation which was not treated...

Pilot-Scale Production of Group A and Group C Meningococcal Polysaccharide Immunogens

Berman, Sanford, Altieri, Patricia L., Groffinger, Albert, Lowenthal, Joseph P.

Methods have been developed for the pilot-scale production of group A and group C meningococcal polysaccharide immunogens based on the meningococcal strains, the medium, and the basic processing...

Freeze-drying Various Strains of Shigella

Berman, Sanford, Altieri, Patricia L., Groffinger, Albert, Lowenthal, Joseph P., Formal, Samuel B.

Of six candidate strains of Shigella prepared in Brain Heart Infusion broth as freeze-dried vaccine, low survival rates were obtained with two of the most promising strains. Survival rates with these...

Bacterial Vaccine in Multidose Tablet Form for Parenteral Use

Berman, Sanford, Lowenthal, Joseph P., Grogan, Earl W., Altieri, Patricia L., Benenson, Abram S.

Dried typhoid vaccines were prepared by freeze-drying of heat-inactivated phenolized-cell suspensions and by an acetone-killed and dried technique. Portions of the dried powder obtained by each...

Western Equine Encephalomyelitis Vaccine Produced in Chick Embryo Cell Cultures

Robinson, David M., Berman, Sanford, Lowenthal, Joseph P., Hetrick, Frank M.

A method was developed for production of a freeze-dried Western equine encephalomyelitis vaccine from virus propagated in chick embryo cell culture monolayers maintained with a serum-free medium. A...

Diagnostic Antigens and Antisera in Tablet Form

Berman, Sanford, Vincent, Gary, Altieri, Patricia L., Lowenthal, Joseph P.

Diagnostic antigen suspensions and antisera can be prepared in tablet form with no loss in potency.

FACTORS AFFECTING THE ELABORATION BY CLOSTRIDIUM HISTOLYTICUM OF PROTEINASES CAPABLE OF DEBRIDING THIRD DEGREE BURN ESCHARS ON GUINEA PIGS

Berman, Sanford, Lowenthal, Joseph P., Webster, Marion E., Altieri, Patricia L., Gochenour, Raymond B.

Berman, Sanford (Walter Reed Army Institute of Research, Washington, D. C.), Joseph P. Lowenthal, Marion E. Webster, Patricia L. Altieri, and Raymond B. Gochenour. Factors affecting the elaboration...

LARGE SCALE PURIFICATION OF PROTEINASES FROM CLOSTRIDIUM HISTOLYTICUM FILTRATES

Conklin, David A., Webster, Marion E., Altieri, Patricia L., Berman, Sanford, Lowenthal, Joseph P., Gochenour, Raymond B.

Conklin, David A. (Walter Reed Army Institute of Research, Washington, D. C.), Marion E. Webster, Patricia L. Altieri, Sanford Berman, Joseph P. Lowenthal, and Raymond B. Gochenour. Large scale...

ENZYMATIC DEBRIDEMENT OF THIRD-DEGREE BURNS ON GUINEA PIGS BY CLOSTRIDIUM HISTOLYTICUM PROTEINASES

Webster, Marion E., Altieri, Patricia L., Conklin, David A., Berman, Sanford, Lowenthal, Joseph P., Gochenour, Raymond B.

Webster, Marion E. (Walter Reed Army Institute of Research, Washington, D. C.), Patricia L. Altieri, David A. Conklin, Sanford Berman, Joseph P. Lowenthal, and Raymond B. Gochenour. Enzymatic...

Mouse Potency Assay for Western Equine Encephalomyelitis Vaccines

Robinson, David M., Berman, Sanford, Lowenthal, Joseph P.

A potency assay for Western equine encephalomyelitis vaccine was developed which utilized mice as the test animal instead of guinea pigs or hamsters. By immunizing several groups of mice with...

Stable Reagent for the Detection of Antibody to the Specific Fraction I Antigen of Yersinia pestis1

Rust, James H., Berman, Sanford, Habig, William H., Marshall, John D., Cavanaugh, Dan C.

A stable hemagglutinating antigen for detection of fraction I (FR-I) antibody of Yersinia pestis (Pasteurella pestis) is described. The antigen was prepared by sensitizing tanned,...

Preparation of Purified Suspensions of Coxiella burneti by Genetron Extraction Followed by Continuous-Flow Ultracentrifugation1

Dubois, Doria R., Cutchins, Ernest C., Berman, Sanford, Lowenthal, Joseph P., Timchak, Robert L.

A method for the preparation of purified suspensions of Coxiella burneti by Genetron extraction followed by continuous-flow density gradient ultracentrifugation is described. Both phases of the...

Comparative Immunogenicities of Chikungunya Vaccines Propagated in Monkey Kidney Monolayers and Chick Embryo Suspension Cultures

White, Arthur, Berman, Sanford, Lowenthal, Joseph P.

A comparative study was made of Formalin-inactivated Chikungunya vaccines prepared from the virus propagated in African green monkey kidney monolayers and concentrated chick embryo suspension...

Preparation of Cholera Vaccines by Fluorocarbon Extraction of Cholera Vibrio Suspensions

Altieri, Patricia L., Berman, Sanford, Groffinger, Albert, Lowenthal, Joseph P.

Experimental cholera vaccines were prepared from suspensions of cholera vibrios which were extracted with Genetron-113. These vaccines, when compared with a control preparation which was not treated...

Pilot-Scale Production of Group A and Group C Meningococcal Polysaccharide Immunogens

Berman, Sanford, Altieri, Patricia L., Groffinger, Albert, Lowenthal, Joseph P.

Methods have been developed for the pilot-scale production of group A and group C meningococcal polysaccharide immunogens based on the meningococcal strains, the medium, and the basic processing...

Freeze-drying Various Strains of Shigella

Berman, Sanford, Altieri, Patricia L., Groffinger, Albert, Lowenthal, Joseph P., Formal, Samuel B.

Of six candidate strains of Shigella prepared in Brain Heart Infusion broth as freeze-dried vaccine, low survival rates were obtained with two of the most promising strains. Survival rates with these...

Bacterial Vaccine in Multidose Tablet Form for Parenteral Use

Berman, Sanford, Lowenthal, Joseph P., Grogan, Earl W., Altieri, Patricia L., Benenson, Abram S.

Dried typhoid vaccines were prepared by freeze-drying of heat-inactivated phenolized-cell suspensions and by an acetone-killed and dried technique. Portions of the dried powder obtained by each...

Western Equine Encephalomyelitis Vaccine Produced in Chick Embryo Cell Cultures

Robinson, David M., Berman, Sanford, Lowenthal, Joseph P., Hetrick, Frank M.

A method was developed for production of a freeze-dried Western equine encephalomyelitis vaccine from virus propagated in chick embryo cell culture monolayers maintained with a serum-free medium. A...

Potency of killed plague vaccines prepared from avirulent Yersinia pestis*

Williams, James E., Altieri, Patricia L., Berman, Sanford, Lowenthal, Joseph P., Cavanaugh, Dan C.

Killed plague vaccines prepared from avirulent strains A1122 and EV76S of Yersinia pestis were more effective in mouse potency tests than samples of Plague Vaccine, USP, prepared from killed Y....