Santiago Schnell

Should digestion assays be used to estimate persistence of potential allergens in tests for safety of novel food proteins? (2009)

Schnell, Santiago, Herman, Rod A

Abstract Food allergies affect an estimated 3 to 4% of adults and up to 8% of children in developed western countries. Results from in vitro simulated gastric digestion studies with purified proteins...

RESEARCH ARTICLE Reconstructing biochemical pathways from time course data (2008)

Jeyaraman Srividhya, Edmund J. Crampin, Patrick E. Mcsharry, Santiago Schnell

Time series data on biochemical reactions reveal transient behavior, away from chemical equilibrium, and contain information on the dynamic interactions among reacting components. However, this...

A multiscale mathematical model of cancer, and its use in analyzing irradiation therapies (2006)

Ribba, Benjamin, Colin, Thierry, Schnell, Santiago

Background: Radiotherapy outcomes are usually predicted using the Linear Quadratic model. However, this model does not integrate complex features of tumor growth, in particular cell cycle regulation....

Is the intrinsic disorder of proteins the cause of the scale-free architecture of protein-protein interaction networks? (2006)

Schnell, Santiago, Fortunato, Santo, Roy, Sourav

In protein-protein interaction networks certain topological properties appear to be recurrent: networks maps are considered scale-free. It is possible that this topology is reflected in the protein...

A multiscale mathematical model of cancer, and its use in analyzing irradiation therapies (2006)

Ribba, Benjamin, Colin, Thierry, Schnell, Santiago

Abstract Background Radiotherapy outcomes are usually predicted using the Linear Quadratic model. However, this model does not integrate complex features of tumor growth, in particular cell cycle...

� NWB Tool Overview and Demo – Weixia (Bonnie) Huang (2005)

Investigators Katy Börner, Albert-laszlo Barabasi, Santiago Schnell, Ro Vespignani, Stanley Wasserman, Eric Wernert, ...

Goal: Develop a large-scale network analysis, modeling and visualization toolkit for physics, biomedical, and social science research. Amount: $1,120,926, NSF IIS-0513650 award

Outline (2005)

Weixia (bonnie Huang, Investigators Katy Börner, Albert-laszlo Barabasi, Santiago Schnell, Ro Vespignani, Stanley Wasserman, ...

Goal: Develop a large-scale network analysis, modeling and visualization toolkit for physics, biomedical, and social science research. Amount: $1,120,926, NSF IIS-0513650 award

� Symmetric vs. Asymmetric matrix (2005)

Weixia (bonnie Huang, Katy Börner, Albert-laszlo Barabasi, Santiago Schnell, Ro Vespignani, Stanley Wasserman, ...

Goal: Develop a large-scale network analysis, modeling and visualization toolkit for physics, biomedical, and social science research. Amount: $1,120,926, NSF IIS-0513650 award

Extracting biochemical reaction kinetics from time series data (2004)

Edmund J. Crampin, Patrick E. Mcsharry, Santiago Schnell

Abstract. We consider the problem of inferring kinetic mechanisms for biochemical reactions from time series data. Using a priori knowledge about the structure of chemical reaction kinetics we...

Extracting biochemical reaction kinetics from time series data (2004)

Edmund J. Crampin, Patrick E. Mcsharry, Santiago Schnell

Abstract. We consider the problem of inferring kinetic mechanisms for biochemical reactions from time series data. Using a priori knowledge about the structure of chemical reaction kinetics we...

Should digestion assays be used to estimate persistence of potential allergens in tests for safety of novel food proteins?

Schnell, Santiago, Herman, Rod A

Food allergies affect an estimated 3 to 4% of adults and up to 8% of children in developed western countries. Results from in vitro simulated gastric digestion studies with purified proteins are...

How can mathematics help us explore vertebrate segmentation?

Baker, Ruth E., Schnell, Santiago

Since the discovery of gene products oscillating during the formation of vertebral segments, much attention has been directed toward eluciating the molecular basis of the so-called segmentation...