Depletion of BRCA1 impairs differentiation but enhances proliferation of mammary epithelial cells
Furuta, Saori, Jiang, Xianzhi, Gu, Bingnan, Cheng, Eric, Chen, Phang-Lang, Lee, Wen-Hwa
Cumulative evidence indicates that breast cancer-associated gene 1 (BRCA1) participates in DNA damage repair and cell-cycle checkpoint control, serving as a tumor susceptibility gene to maintain the...
Furuta, Saori, Ortiz, Fausto, Zhu Sun, Xiu, Wu, Hsiao-Huei, Mason, Andrew, Momand, Jamil
The p53 tumour-suppressor protein is a transcription factor that activates the expression of genes involved in cell cycle arrest, apoptosis and DNA repair. The p53 protein is vulnerable to oxidation...
Depletion of BRCA1 impairs differentiation but enhances proliferation of mammary epithelial cells
Furuta, Saori, Jiang, Xianzhi, Gu, Bingnan, Cheng, Eric, Chen, Phang-Lang, Lee, Wen-Hwa
Cumulative evidence indicates that breast cancer-associated gene 1 (BRCA1) participates in DNA damage repair and cell-cycle checkpoint control, serving as a tumor susceptibility gene to maintain the...
Furuta, Saori, Ortiz, Fausto, Zhu Sun, Xiu, Wu, Hsiao-Huei, Mason, Andrew, Momand, Jamil
The p53 tumour-suppressor protein is a transcription factor that activates the expression of genes involved in cell cycle arrest, apoptosis and DNA repair. The p53 protein is vulnerable to oxidation...