Sara E. Melville

The DNA sequence of chromosome I of an African trypanosome: gene content, chromosome organisation, recombination and polymorphism (2003)

Hall, Neil, Berriman, Matthew, Lennard, Nicola J., Harris, Barbara R., Hertz-Fowler, Christiane, Bart-Delabesse, Emmanuelle N., ...

The African trypanosome, Trypanosoma brucei, causes sleeping sickness in humans in sub-Saharan Africa. Here we report the sequence and analysis of the 1.1 Mb chromosome I, which encodes approximately...

Predominance of Duplicative VSG Gene Conversion in Antigenic Variation in African Trypanosomes

Robinson, Nicholas P., Burman, Nils, Melville, Sara E., Barry, J. David

A number of mechanisms have been described by which African trypanosomes undergo the genetic switches that differentially activate their variant surface glycoprotein genes (VSGs) and bring about...

A New, Expressed Multigene Family Containing a Hot Spot for Insertion of Retroelements Is Associated with Polymorphic Subtelomeric Regions of Trypanosoma brucei

Bringaud, Frédéric, Biteau, Nicolas, Melville, Sara E., Hez, Stéphanie, El-Sayed, Najib M., Leech, Vanessa, ...

We describe a novel gene family that forms clusters in subtelomeric regions of Trypanosoma brucei chromosomes and partially accounts for the observed clustering of retrotransposons. The ingi and...

The DNA sequence of chromosome I of an African trypanosome: gene content, chromosome organisation, recombination and polymorphism

Hall, Neil, Berriman, Matthew, Lennard, Nicola J., Harris, Barbara R., Hertz-Fowler, Christiane, Bart-Delabesse, Emmanuelle N., ...

The African trypanosome, Trypanosoma brucei, causes sleeping sickness in humans in sub-Saharan Africa. Here we report the sequence and analysis of the 1.1 Mb chromosome I, which encodes approximately...

Predominance of Duplicative VSG Gene Conversion in Antigenic Variation in African Trypanosomes

Robinson, Nicholas P., Burman, Nils, Melville, Sara E., Barry, J. David

A number of mechanisms have been described by which African trypanosomes undergo the genetic switches that differentially activate their variant surface glycoprotein genes (VSGs) and bring about...

A New, Expressed Multigene Family Containing a Hot Spot for Insertion of Retroelements Is Associated with Polymorphic Subtelomeric Regions of Trypanosoma brucei

Bringaud, Frédéric, Biteau, Nicolas, Melville, Sara E., Hez, Stéphanie, El-Sayed, Najib M., Leech, Vanessa, ...

We describe a novel gene family that forms clusters in subtelomeric regions of Trypanosoma brucei chromosomes and partially accounts for the observed clustering of retrotransposons. The ingi and...

The DNA sequence of chromosome I of an African trypanosome: gene content, chromosome organisation, recombination and polymorphism

Hall, Neil, Berriman, Matthew, Lennard, Nicola J., Harris, Barbara R., Hertz-Fowler, Christiane, Bart-Delabesse, Emmanuelle N., ...

The African trypanosome, Trypanosoma brucei, causes sleeping sickness in humans in sub-Saharan Africa. Here we report the sequence and analysis of the 1.1 Mb chromosome I, which encodes approximately...