Sara Martínez-Martínez

Selective Inhibition of Vascular Endothelial Growth Factor–mediated Angiogenesis by Cyclosporin A: Roles of the Nuclear Factor of Activated T Cells and Cyclooxygenase 2 (2001)

Hernández, Gabriela L., Volpert, Olga V., Iñiguez, Miguel A., Lorenzo, Elisa, Martínez-Martínez, Sara, Grau, Raquel, ...

Cyclosporin A (CsA) is an immunosuppressive drug that inhibits the activity of transcription factors of the nuclear factor of activated T cells (NFAT) family, interfering with the induction of...

Vascular endothelial growth factor activates nuclear factor of activated T cells in human endothelial cells: a role for tissue factor gene expression. (1999)

Armesilla, Angel Luis, Lorenzo, Elisa, Gómez Del Arco, Pablo, Martínez-Martínez, Sara, Alfranca, Arantzazu, Redondo, Juan Miguel

Vascular endothelial growth factor (VEGF) is a potent angiogenic inducer that stimulates the expression of tissue factor (TF), the major cellular initiator of blood coagulation. Here we show that...

Antioxidants and AP-1 activation: a brief overview. (1997)

Gómez Del Arco, Pablo, Martínez-Martínez, Sara, Calvo, Victor, Armesilla, Angel Luis, Redondo, Juan Miguel

Metadata only

Blockade of T-cell activation by dithiocarbamates involves novel mechanisms of inhibition of nuclear factor of activated T cells. (1997)

Martínez-Martínez, Sara, Gómez Del Arco, Pablo, Armesilla, Angel Luis, Aramburu, Jose, Luo, Chun, Rao, Anjana, ...

Dithiocarbamates (DTCs) have recently been reported as powerful inhibitors of NF-kappaB activation in a number of cell types. Given the role of this transcription factor in the regulation of gene...

JNK (c-Jun NH2-terminal kinase) is a target for antioxidants in T lymphocytes. (1996)

Gómez Del Arco, Pablo, Martínez-Martínez, Sara, Calvo, Victor, Armesilla, Angel Luis, Redondo, Juan Miguel

AP-1 has been shown to behave as a redox-sensitive transcription factor that can be activated by both oxidant and antioxidant stimuli. However, the mechanisms involved in the activation of AP-1 by...

Vascular Endothelial Growth Factor Activates Nuclear Factor of Activated T Cells in Human Endothelial Cells: a Role for Tissue Factor Gene Expression

Armesilla, Angel Luis, Lorenzo, Elisa, Gómez Del Arco, Pablo, Martínez-Martínez, Sara, Alfranca, Arantzazu, Redondo, Juan Miguel

Vascular endothelial growth factor (VEGF) is a potent angiogenic inducer that stimulates the expression of tissue factor (TF), the major cellular initiator of blood coagulation. Here we show that...

Vascular Endothelial Growth Factor Activates Nuclear Factor of Activated T Cells in Human Endothelial Cells: a Role for Tissue Factor Gene Expression

Armesilla, Angel Luis, Lorenzo, Elisa, Gómez Del Arco, Pablo, Martínez-Martínez, Sara, Alfranca, Arantzazu, Redondo, Juan Miguel

Vascular endothelial growth factor (VEGF) is a potent angiogenic inducer that stimulates the expression of tissue factor (TF), the major cellular initiator of blood coagulation. Here we show that...

Selective Inhibition of Vascular Endothelial Growth Factor–Mediated Angiogenesis by Cyclosporin a: Roles of the Nuclear Factor of Activated T Cells and Cyclooxygenase 2

Hernández, Gabriela L., Volpert, Olga V., Íñiguez, Miguel A., Lorenzo, Elisa, Martínez-Martínez, Sara, Grau, Raquel, ...

Cyclosporin A (CsA) is an immunosuppressive drug that inhibits the activity of transcription factors of the nuclear factor of activated T cells (NFAT) family, interfering with the induction of...

The RCAN carboxyl end mediates calcineurin docking-dependent inhibition via a site that dictates binding to substrates and regulators

Martínez-Martínez, Sara, Genescà, Lali, Rodríguez, Antonio, Raya, Alicia, Salichs, Eulàlia, Were, Felipe, ...

Specificity of signaling kinases and phosphatases toward their targets is usually mediated by docking interactions with substrates and regulatory proteins. Here, we characterize the motifs involved...

Cooperative Synergy between NFAT and MyoD Regulates Myogenin Expression and Myogenesis*S⃞

Armand, Anne-Sophie, Bourajjaj, Meriem, Martínez-Martínez, Sara, Azzouzi, Hamid El, Da Costa Martins, Paula A., Hatzis, Pantelis, ...

Calcineurin/NFAT signaling is involved in multiple aspects of skeletal muscle development and disease. The myogenic basic helix-loop-helix transcription factors, MyoD, myogenin, Myf5, and MRF4...