Sarah R. Oikemus

Epigenetic Telomere Protection by Drosophila DNA Damage Response Pathways: A Dissertation (2006)

Oikemus, Sarah R.

Several aspects of Drosophila telomere biology indicate that telomere protection can be regulated by an epigenetic mechanism. First, terminally deleted chromosomes can be stably inherited and do not...

Epigenetic telomere protection by Drosophila DNA damage response pathways (2006)

Oikemus, Sarah R., Queiroz-Machado, Joana, Lai, KuanJu, McGinnis-Schultz, Nadine, Sunkel, Claudio E., Brodsky, Michael H.

Analysis of terminal deletion chromosomes indicates that a sequence-independent mechanism regulates protection of Drosophila telomeres. Mutations in Drosophila DNA damage response genes such as...

Epigenetic Telomere Protection by Drosophila DNA Damage Response Pathways (2006)

Sarah R. Oikemus, Joana Queiroz-Machado, KuanJu Lai, Nadine McGinnis, Claudio Sunkel, Michael H. Brodsky

Analysis of terminal deletion chromosomes indicates that a sequence-independent mechanism regulates protection of Drosophila telomeres. Mutations in Drosophila DNA damage response genes such as...

Epigenetic telomere protection by Drosophila DNA damage response pathways (2006)

Sarah R Oikemus, Joana Queiroz-Machado, KuanJu Lai, Nadine M McGinnis, Claudio E. Sunkel, Michael H Brodsky

Analysis of terminal deletion chromosomes indicates that a sequence-independent mechanism regulates protection of Drosophila telomeres. Mutations in Drosophila DNA damage response genes such as...

Epigenetic telomere protection by Drosophila DNA damage response pathways : a dissertation / (2006)

Oikemus, Sarah R.

Thesis (Ph.D.)--University of Massachusetts Graduate School of Biomedical Sciences, 2006.

Drosophila atm/telomere fusion is required for telomeric localization of HP1 and telomere position effect (2004)

Oikemus, Sarah R., McGinnis-Schultz, Nadine, Queiroz-Machado, Joana, Tukachinsky, Hanna, Takada, Saeko, Sunkel, Claudio E., ...

Terminal deletions of Drosophila chromosomes can be stably protected from end-to-end fusion despite the absence of all telomere-associated sequences. The sequence-independent protection of these...

Identification of genes that synergize with Cbfb-MYH11 in the pathogenesis of acute myeloid leukemia (2004)

Castilla, Lucio H., Perrat, Paola N., Martinez, Natalia J., Landrette, Sean F., Keys, R., Oikemus, Sarah R., ...

Acute myeloid leukemia subtype M4 with eosinophilia is associated with a chromosome 16 inversion that creates a fusion gene CBFB-MYH11. We have previously shown that CBFB-MYH11 is necessary but not...

Drosophila atm/telomere fusion is required for telomeric localization of HP1 and telomere position effect (2004)

Oikemus, Sarah R., McGinnis, Nadine, Queiroz-Machado, Joana, Tukachinsky, Hanna, Takada, Saeko, Sunkel, Claudio E., ...

Terminal deletions of Drosophila chromosomes can be stably protected from end-to-end fusion despite the absence of all telomere-associated sequences. The sequence-independent protection of these...

Drosophila atm/telomere fusion is required for telomeric localization of HP1 and telomere position effect (2004)

Oikemus, Sarah R., McGinnis, Nadine, Queiroz-Machado, Joana, Tukachinsky, Hanna, Takada, Saeko, Sunkel, Claudio E., ...

Terminal deletions of Drosophila chromosomes can be stably protected from end-to-end fusion despite the absence of all telomere-associated sequences. The sequence-independent protection of these...

Drosophila atm/telomere fusion is required for telomeric localization of HP1 and telomere position effect (2004)

Oikemus, Sarah R., McGinnis, Nadine, Queiroz-Machado, Joana, Tukachinsky, Hanna, Takada, Saeko, Sunkel, Claudio E., ...

Terminal deletions of Drosophila chromosomes can be stably protected from end-to-end fusion despite the absence of all telomere-associated sequences. The sequence-independent protection of these...

The death domain kinase RIP1 is essential for tumor necrosis factor alpha signaling to p38 mitogen-activated protein kinase (2003)

Lee, Thomas H., Huang, Qiaojia, Oikemus, Sarah R., Shank, Jennifer, Ventura, Juan-Jose, Cusson, Nicole, ...

The cytokine tumor necrosis factor alpha (TNF-alpha) stimulates the NF-kappaB, SAPK/JNK, and p38 mitogen-activated protein (MAP) kinase pathways by recruiting RIP1 and TRAF2 proteins to the tumor...

The death domain kinase RIP protects thymocytes from tumor necrosis factor receptor type 2-induced cell death (2002)

Hermance, Nicole M., Oikemus, Sarah R., Kilpatrick, Elizabeth D., Cunningham, Leslie A., Kelliher, Michelle

Fas and the tumor necrosis factor receptor (TNFR)1 regulate the programmed cell death of lymphocytes. The death domain kinase, receptor interacting protein (rip), is recruited to the TNFR1 upon...

The DNA binding activity of TAL-1 is not required to induce leukemia/lymphoma in mice (2001)

O'Neil, Jennifer Elinor, Billa, Marilisa, Oikemus, Sarah R., Kelliher, Michelle

Activation of the basic helix-loop-helix (bHLH) gene TAL-1 (or SCL) is the most frequent gain-of-function mutation in pediatric T cell acute lymphoblastic leukemia (T-ALL). Similarly, mis-expression...

Drosophila atm/telomere fusion is required for telomeric localization of HP1 and telomere position effect

Oikemus, Sarah R., McGinnis, Nadine, Queiroz-Machado, Joana, Tukachinsky, Hanna, Takada, Saeko, Sunkel, Claudio E., ...

Terminal deletions of Drosophila chromosomes can be stably protected from end-to-end fusion despite the absence of all telomere-associated sequences. The sequence-independent protection of these...

Epigenetic Telomere Protection by Drosophila DNA Damage Response Pathways

Oikemus, Sarah R, Queiroz-Machado, Joana, Lai, KuanJu, McGinnis, Nadine, Sunkel, Claudio, Brodsky, Michael H

Analysis of terminal deletion chromosomes indicates that a sequence-independent mechanism regulates protection of Drosophila telomeres. Mutations in Drosophila DNA damage response genes such as...

Drosophila atm/telomere fusion is required for telomeric localization of HP1 and telomere position effect

Oikemus, Sarah R., McGinnis, Nadine, Queiroz-Machado, Joana, Tukachinsky, Hanna, Takada, Saeko, Sunkel, Claudio E., ...

Terminal deletions of Drosophila chromosomes can be stably protected from end-to-end fusion despite the absence of all telomere-associated sequences. The sequence-independent protection of these...

Epigenetic Telomere Protection by Drosophila DNA Damage Response Pathways

Oikemus, Sarah R, Queiroz-Machado, Joana, Lai, KuanJu, McGinnis, Nadine, Sunkel, Claudio, Brodsky, Michael H

Analysis of terminal deletion chromosomes indicates that a sequence-independent mechanism regulates protection of Drosophila telomeres. Mutations in Drosophila DNA damage response genes such as...