The Pituitary Function of Androgen Receptor Constitutes a Glucocorticoid Production Circuit▿
Miyamoto, Junko, Matsumoto, Takahiro, Shiina, Hiroko, Inoue, Kazuki, Takada, Ichiro, Ito, Saya, ...
Androgen receptor (AR) mediates diverse androgen actions, particularly reproductive processes in males and females. AR-mediated androgen signaling is considered to also control metabolic processes;...
Zhao, Yue, Takeyama, Ken-ichi, Sawatsubashi, Shun, Ito, Saya, Suzuki, Eriko, Yamagata, Kaoru, ...
Ligand-bound nuclear receptors (NR) activate transcription of the target genes. This activation is coupled with histone modifications and chromatin remodeling through the function of various...
Aberrant E2F activation by polyglutamine expansion of androgen receptor in SBMA neurotoxicity
Suzuki, Eriko, Zhao, Yue, Ito, Saya, Sawatsubashi, Shun, Murata, Takuya, Furutani, Takashi, ...
Spinal and bulbar muscular atrophy (SBMA) is a neurodegenerative disorder caused by a polyglutamine repeat (polyQ) expansion within the human androgen receptor (AR). Unlike other neurodegenerative...