Seiji INOUE

Thrombocytopenia in Preterm Infants with Intrauterine Growth Restriction (2008)

Maruyama, Hidehiko, Shinozuka, Masako, Kondoh, Yo-ichi, Akahori, Yo-ichiro, Matsuda, Miwa, Inoue, Seiji, ...

Sick preterm infants often have thrombocytopenia at birth, and this is often associated with intrauterine growth restriction (IUGR), or birth weights less than the 10th percentile. The pathogenesis...

Basic Study of Susceptibility-Weighted Imaging at 1.5T (2008)

Matsushita, Toshi, Anami, Daigo, Arioka, Tadashi, Inoue, Seiji, Kariya, Yusuke, Fujimoto, Masako, ...

With the aim of sequence optimization in susceptibility-weighted imaging (SWI), 2 image acquisition parameters (slice thickness and matrix size) and 2 image processing conditions (number of slices...

Roles of Asp126 and Asp156 in the Enzyme Function of Sphingomyelinase from Bacillus cereus (1999)

Fujii, Shinobu, Ogata, Kenji, Inoue, Bunpei, Inoue, Seiji, Murakami, Masahiro, Iwama, Seiji, ...

To elucidate the roles of conserved Asp residues of Bacillus cereus sphingomyelinase (SMase) in the kinetic and binding properties of the enzyme toward various substrates and Mg2+, the kinetic...

Isolation and Amino Acid Sequence of a Phospholipase A2 Inhibitor from the Blood Plasma of the Sea Krait, Laticauda semifasciata (1999)

Ohkura, Naoki, Kitahara, Yoshiya, Inoue, Seiji, Ikeda, Kiyoshi, Hayashi, Kyozo

A phospholipase A2 (PLA2) inhibitor was purified from the blood plasma of a sea krait, Laticauda semifasciata, by sequential chromatography on Sephadex G–200, Mono Q, and Phenyl Sepharose columns....

Mg2+ Binding and Catalytic Function of Sphingomyelinase from Bacillus cereus (1998)

Fujii, Shinobu, Inoue, Bunpei, Yamamoto, Hiroki, Ogata, Kenji, Shinki, Tomohiro, Inoue, Seiji, ...

The modes of Mg2+ binding to SMase from Bacillus cereus were studied on the basis of the changes in the tryptophyl fluorescence intensity. This enzyme was shown to possess at least two binding...

Binding Mode of Phospholipase A2 with a New Type of Phospholipid Analog Having an Oxazolidinone Ring (1995)

Tani, Takeshi, Fujii, Shinobu, Inoue, Seiji, Ikeda, Kiyoshi, Iwama, Seiji, Matsuda, Takeshi, ...

Inhibition of phospholipases A2 (PLA2s) by a new type of monodispersed phospholipid analog, 3-dodecanoyl-4-phosphatidylcholinohydroxymethyl-2-oxazolidinone (oxazolidinone-PC), was investigated by the...

Role of Ca2+ in the Binding of Phospholipase A2 with a Monomeric Substrate and with Its Amide-Type Analog (1994)

Fujii, Shinobu, Tani, Takeshi, Hada, Shuji, Inoue, Seiji, Ikeda, Kiyoshi, Iwama, Seiji, ...

Effects of Ca2+ on the kinetic parameters for the hydrolysis of monodispersed 1, 2-dihex-anoyl-sn-glycero-3-phosphorylcholine (diC6PC), catalyzed by Group I phospholipases A2 (PLA2s) from Pseudechis...

Hydrolysis of Micellar Diheptanoylphosphatidylcholine Catalyzed by Bovine Pancreatic Phospholipase A2: Kinetic Characterization of Group I and II Enzymes (1993)

Hada, Shuji, Fujii, Shinobu, Inoue, Seiji, Ikeda, Kiyoshi, Teshima, Keizo

Initial velocity data for the hydrolysis of micellar l,2-diheptanoyl-sn-glycero-3-phosphorylcholine (diC7PC) catalyzed by bovine pancreatic PLA2 (Group I) were analyzed using the Michaelis-Menten...

Kinetics of the Hydrolysis of Micellar Substrates Catalyzed by Snake Venom Phospholipases A2 (1992)

Nishimura, Hiroko, Inoue, Seiji, Ikeda, Kiyoshi, Teshima, Keizo, Samejima, Yuji, Omori-Satoh, Tamotsu, ...

Effects of Ca2+ on the kinetic parameters for the hydrolysis of mixed micelles of 1,2-dipalmitoyl-sn-glycero-3-phosphorylcholine (diC16PC) with Triton X-100, catalyzed by a cobra (Naja naja...

Kinetics of the Hydrolysis of Monodispersed and Micellar Phosphatidylcholines Catalyzed by a Phospholipase C from Bacillus cereus (1991)

Ikeda, Kiyoshi, Inoue, Seiji, Amasaki, Chika, Teshima, Keizo, Ikezawa, Hiroh

The phosphatidylcholine-hydrolyzing phospholipase C, so-called “phospholipase C” (PLC), was isolated from the culture of Bacillus cereus strain IAM 1208. The amino-acid composition and partial...

Kinetics of the Hydrolysis of Monodispersed Dihexanoylphosphatidylcholine Catalyzed by Bovine Pancreatic Phospholipase A2: Roles of Ca2+ Binding and Ionizations of Amino Acid Residues in the Active Site (1991)

Fujii, Shinobu, Inoue, Toshihiko, Inoue, Seiji, Ikeda, Kiyoshi

Phospholipases A2 (PLA2s) are classified into two groups, I and II, according to differences in the polypeptide-chain length and intramolecular disulfide bondings. The hydrolysis of monodispersed...

pH Dependence of the Reaction Rate of His 48 with p-Bromophenacyl Bromide and of the Binding Constant to Ca2+ of the Monomeric Forms of Intact and {alpha}-NH2 Modified Phospholipases A2 from Trimeresurus flavoviridis (1989)

Miyake, Takehiro, Inoue, Seiji, Ikeda, Kiyoshi, Teshima, Keizo, Samejima, Yuji, Omori-Satoh, Tamotsu

The phospholipase A2 of Trimeresurus flavoviridis was found to show monomer-dimer equilibria. Under conditions where the enzyme exists predominantly in the monomeric form, the chemical reaction rate...

Isolation and Fundamental Properties of a Phospholipase A2 Inhibitor from the Blood Plasma of Trimeresurus flavoviridis (1989)

Kogaki, Hiroyuki, Inoue, Seiji, Ikeda, Kiyoshi, Samejima, Yuji, Omori-Satoh, Tamotsu, Hamaguchi, Kozo

Phospholipase A2 inhibitor was purified from the blood plasma of Habu, Trimeresurus flavoviridis, by Sephadex G-200 gel filtration, DEAE-cellulose chromatography, and Blue-Sepharose CL-6B column...

Interactions of Monodispersed and Micellar Substrates with a Phospholipase A2 from Trimeresurus flavoviridis (1989)

Teshima, Keizo, Ikeda, Kiyoshi, Miyake, Takehiro, Imamura, Mitsuo, Inoue, Seiji, Samejima, Yuji, ...

Bindings of the phospholipase A2 from Trimeresurus flavoviridis to the monodispersed and micellar n-alkylphosphorylcholines (n-CnPC) were studied at 25°C and ionic strength 0.2 by the aromatic CD...

Developmental Variation and Amino Acid Sequences of Cytochromes c of the Fruit Fly Drosophila melanogaster and the Flesh Fly Boettcherisca peregrina (1986)

INOUE, Seiji, INOUE, Hiroaki, HIROYOSHI, Toshiki, MATSUBARA, Hiroshi, YAMANAKA, Tateo

The amino acid sequences of cytochromes c purified from the fruit fly Drosophila melanogaster and the flesh fly Boettcherisca peregrina were determined. In contrast with the case of the housefly,...

Complete Amino Acid Sequence of Cytochrome c from the Honeybee, Apis mellifera, and Evolutionary Relationship of the Honeybee to Other Insects on the Basis of the Amino Acid Sequence (1985)

INOUE, Seiji, MATSUBARA, Hiroshi, YAMANAKA, Tateo

The complete amino acid sequence of cytochrome c purified from the honeybee, Apis mellifera was determined. Only one molecular species of cytochrome c was found in the honeybee throughout its...

Structural Difference between Larval and Adult Cytochromes c of the Housefly, Musca domestica (1980)

YAMANAKA, Tateo, INOUE, Seiji, HIROYOSHI, Toshiki

The structural difference between larval and adult cytochromes c of the housefly, Musca domestica was studied. The two cytochromes differed in electrophoretic behavior and amino acid composition from...