Hiroshi Watanabe, Seiryo Sugiura, Hidenobu Kafuku, Toshiaki Hisada
ABSTRACT To relate the subcellular molecular events to organ level physiology in heart, we have developed a threedimensional finite-element-based simulation program incorporating the cellular...
Nishimura, Satoshi, Kawai, Yasuo, Nakajima, Toshiaki, Hosoya, Yumiko, Fujita, Hideo, Katoh, Masayoshi, ...
Objective: To elucidate the interdependence between the mechanical state of the myocardium and its electrical activity, previous studies have been performed at the cellular level. However, the...
Yamashita, Hiroshi, Sugiura, Seiryo, Fujita, Hideo, Yasuda, So-ichiro, Nagai, Ryozo, Saeki, Yasutake, ...
Objective: To investigate the functional role of myosin light chain (MLC) isoforms in cardiac muscles, we examined the motor function of two different myosins the structure of which differed only in...
Actin--myosin interaction (1999)
Recent advances in the study of muscle physiology was made possible by the application of novel experimental techniques including in vitro motility assay, molecular biology, and X-ray...
Sugiura, Seiryo, Harada, Kazumasa, Yokoyama, Ikuo, Momomura, Shin-ichi, Naruse, Yosihiro, Maku-uchi, Haruo, ...
Objective: The clinical use of skeletal muscle cardiomyoplasty is limited because of its inadequate haemodynamic benefits. To facilitate experimental and clinical efforts to improve the efficacy of...
Watanabe, Hiroshi, Sugiura, Seiryo, Kafuku, Hidenobu, Hisada, Toshiaki
To relate the subcellular molecular events to organ level physiology in heart, we have developed a three-dimensional finite-element-based simulation program incorporating the cellular mechanisms of...
Watanabe, Hiroshi, Sugiura, Seiryo, Kafuku, Hidenobu, Hisada, Toshiaki
To relate the subcellular molecular events to organ level physiology in heart, we have developed a three-dimensional finite-element-based simulation program incorporating the cellular mechanisms of...
In vivo imaging in mice reveals local cell dynamics and inflammation in obese adipose tissue
Nishimura, Satoshi, Manabe, Ichiro, Nagasaki, Mika, Seo, Kinya, Yamashita, Hiroshi, Hosoya, Yumiko, ...
To assess physiological and pathophysiological events that involve dynamic interplay between multiple cell types, real-time, in vivo analysis is necessary. We developed a technique based on confocal...
Sugi, Haruo, Minoda, Hiroki, Inayoshi, Yuhri, Yumoto, Fumiaki, Miyakawa, Takuya, Miyauchi, Yumiko, ...
Despite >50 years of research work since the discovery of sliding filament mechanism in muscle contraction, structural details of the coupling of cyclic cross-bridge movement to ATP hydrolysis are...