Seong-seng Tan

Molecular networks involved in mouse cerebral corticogenesis and spatio-temporal regulation of Sox4and Sox11novel antisense transcripts revealed by transcriptome profiling (2009)

Ling, King-Hwa, Hewitt, Chelsee A, Beissbarth, Tim, Hyde, Lavinia, Banerjee, Kakoli, Cheah, Pike-See, ...

Abstract Background Development of the cerebral cortex requires highly specific spatio-temporal regulation of gene expression. It is proposed that transcriptome profiling of the cerebral cortex at...

Extrinsic Modulation of Retinal Ganglion Cell Projections: Analysis of the Albino Mutation in Pigmentation Mosaic Mice (2007)

Dennis S. Rice, Dan Goldowitz, Robert W. Williams, Kristin Hamre, Patrick T. Johnson, Seong-seng Tan, ...

Tyrosinase is a key enzyme involved in the synthesis of melanin in the retinal pigment epithelium (RPE). Mice that are homozygous for the albino allele at the tyrosinase locus have fewer retinal...

Decreased phosphatidylethanolamine binding protein expression correlates with Aβ accumulation in the Tg2576 mouse model of Alzheimer's disease (2006)

Amee George, Damian Holsinger, R.M., McLean, Catriona A., Tan, Seong-Seng, Scott, Hamish S., Cardamone, Tina, ...

Phosphatidylethanolamine binding protein (PEBP) is a multifunctional protein, with proposed roles as the precursor protein of hippocampal cholinergic neurostimulating peptide (HCNP), and as the Raf...

Decreased phosphatidylethanolamine binding protein expression correlates with Aβ accumulation in the Tg2576 mouse model of Alzheimer's disease (2006)

Amee George, Damian Holsinger, R.M., McLean, Catriona A., Tan, Seong-Seng, Scott, Hamish S., Cardamone, Tina, ...

Phosphatidylethanolamine binding protein (PEBP) is a multifunctional protein, with proposed roles as the precursor protein of hippocampal cholinergic neurostimulating peptide (HCNP), and as the Raf...

Decreased phosphatidylethanolamine binding protein expression correlates with Aβ accumulation in the Tg2576 mouse model of Alzheimer's disease (2006)

George, Amee J., Holsinger, R.M. Damian, McLean, Catriona A., Tan, Seong-Seng, Scott, Hamish S., Cardamone, Tina, ...

Phosphatidylethanolamine binding protein (PEBP) is a multifunctional protein, with proposed roles as the precursor protein of hippocampal cholinergic neurostimulating peptide (HCNP), and as the Raf...

Migratory Response of Interneurons to Different Regions of the Developing Neocortex (2006)

Britto, Joanne M., Obata, Kunihiko, Yanagawa, Yuchio, Tan, Seong-Seng

The interactions between migrating interneurons and their environment that lead to stereotypic migration pathways remain largely undefined. We have used time-lapse imaging to record the migratory...

Statistical modeling of sequencing errors in SAGE libraries (2004)

Beißbarth, Tim, Hyde, Lavinia, Smyth, Gordon K., Job, Chris, Boon, Wee-Ming, Tan, Seong-Seng, ...

Motivation: Sequencing errors may bias the gene expression measurements made by Serial Analysis of Gene Expression (SAGE). They may introduce non-existent tags at low abundance and decrease the real...

MicroSAGE is highly representative and reproducible but reveals major differences in gene expression among samples obtained from similar tissues (2003)

Blackshaw, Seth, Kuo, Winston P, Park, Peter J, Tsujikawa, Motokazu, Gunnersen, Jenny M, Scott, Hamish S, ...

Abstract Background Serial analysis of gene expression using small amounts of starting material (microSAGE) has not yet been conclusively shown to be representative, reproducible or accurate. Results...

Contact-associated Neurite Outgrowth and Branching of Immature Cortical Interneurons (2003)

Sang, Qian, Tan, Seong-Seng

When juvenile interneurons arrive at the cortical environment following tangential migration, they are faced with the task of positioning themselves in cortical space in preparation for local circuit...

Cellular Diversity in Mouse Neocortex Revealed by Multispectral Analysis of Amino Acid Immunoreactivity (2001)

Hill, Elisa, Kalloniatis, Michael, Tan, Seong-Seng

Cortical cells were classified using an unsupervised cluster analysis based upon their quantitative and combinatorial immunoreactivity for glutamate, γ-aminobutyric acid (GABA), aspartate, glutamine...

Glutamate, GABA and Precursor Amino Acids in Adult Mouse Neocortex: Cellular Diversity Revealed by Quantitative Immunocytochemistry (2000)

Hill, Elisa, Kalloniatis, Michael, Tan, Seong-Seng

Glutamate is an important amino acid in the neocortex for metabolic and neurotransmitter functions. The objective of this study was to detect variations in cellular glutamate content using...

MicroSAGE is highly representative and reproducible but reveals major differences in gene expression among samples obtained from similar tissues

Blackshaw, Seth, Kuo, Winston P, Park, Peter J, Tsujikawa, Motokazu, Gunnersen, Jenny M, Scott, Hamish S, ...

Serial analysis of gene expression using small amounts of starting material (microSAGE) is shown to be highly representative, reproducible and accurate, but pronounced differences in gene expression...

A comparative analysis of transcribed genes in the mouse hypothalamus and neocortex reveals chromosomal clustering

Boon, Wee-Ming, Beissbarth, Tim, Hyde, Lavinia, Smyth, Gordon, Gunnersen, Jenny, Denton, Derek A., ...

The hypothalamus and neocortex are subdivisions of the mammalian forebrain, and yet, they have vastly different evolutionary histories, cytoarchitecture, and biological functions. In an attempt to...

MicroSAGE is highly representative and reproducible but reveals major differences in gene expression among samples obtained from similar tissues

Blackshaw, Seth, Kuo, Winston P, Park, Peter J, Tsujikawa, Motokazu, Gunnersen, Jenny M, Scott, Hamish S, ...

Serial analysis of gene expression using small amounts of starting material (microSAGE) is shown to be highly representative, reproducible and accurate, but pronounced differences in gene expression...

A comparative analysis of transcribed genes in the mouse hypothalamus and neocortex reveals chromosomal clustering

Boon, Wee-Ming, Beissbarth, Tim, Hyde, Lavinia, Smyth, Gordon, Gunnersen, Jenny, Denton, Derek A., ...

The hypothalamus and neocortex are subdivisions of the mammalian forebrain, and yet, they have vastly different evolutionary histories, cytoarchitecture, and biological functions. In an attempt to...

Molecular networks involved in mouse cerebral corticogenesis and spatio-temporal regulation of Sox4 and Sox11 novel antisense transcripts revealed by transcriptome profiling

Ling, King-Hwa, Hewitt, Chelsee A, Beissbarth, Tim, Hyde, Lavinia, Banerjee, Kakoli, Cheah, Pike-See, ...

SAGE analysis reveals spatiotemporally regulated transcripts and overlapping sense and antisense transcripts that are important for mouse cerebral cortex development