LTD Induction in Adult Visual Cortex: Role of Stimulus Timing and Inhibition (2007)
Stephen P. Perrett, Serena M. Dudek, David Eagleman, P. Read Montague, Michael J. Friedl
One Hertz stimulation of afferents for 15 min with constant interstimulus intervals (regular stimulation) can induce longterm depression (LTD) of synaptic strength in the neocortex. However, it is...
Dudek, Serena M., Bowen, Wayne D., Bear, Mark F.
Glutamate was found to stimulate the accumulation of 3H - inositol phosphate in synaptoneurosomes prepared from rat neocortex during a narrowly defined period of postnatal development. No glutamate...
Somatic action potentials are sufficient for late-phase LTP-related cell signaling
Dudek, Serena M., Fields, R. Douglas
A question of critical importance confronting neuroscientists today is how biochemical signals initiated at a synapse are conveyed to the nucleus. This problem is particularly relevant to the...
Zhao, Meilan, Adams, J. Paige, Dudek, Serena M.
Synaptic long-term potentiation is maintained through gene transcription, but how the nucleus is recruited remains controversial. Activation of extracellular-signal regulated kinases 1 and 2 (ERKs)...
Somatic action potentials are sufficient for late-phase LTP-related cell signaling
Dudek, Serena M., Fields, R. Douglas
A question of critical importance confronting neuroscientists today is how biochemical signals initiated at a synapse are conveyed to the nucleus. This problem is particularly relevant to the...
Synapse elimination accompanies functional plasticity in hippocampal neurons
Bastrikova, Natalia, Gardner, Gregory A., Reece, Jeff M., Jeromin, Andreas, Dudek, Serena M.
A critical component of nervous system development is synapse elimination during early postnatal life, a process known to depend on neuronal activity. Changes in synaptic strength in the form of...