Sergei Kushnir

The NADPH:Quinone Oxidoreductase P1-{zeta}-crystallin in Arabidopsis Catalyzes the {alpha},{beta}-Hydrogenation of 2-Alkenals: Detoxication of the Lipid Peroxide-Derived Reactive Aldehydes (2002)

Mano, Jun’ichi, Torii, Yoshimitsu, Hayashi, Shun-ichiro, Takimoto, Koichi, Matsui, Kenji, Nakamura, Kaoru, ...

P1-&zgr;-crystallin (P1-ZCr) is an oxidative stress-induced NADPH:quinone oxidoreductase in Arabidopsis thaliana, but its physiological electron acceptors have not been identified. We found that...

Arabidopsis coactivator ALY-like proteins, DIP1 and DIP2, interact physically with the DNA-binding domain of the Zn-finger poly(ADP-ribose) polymerase (2001)

Storozhenko, Sergei, Inzé, Dirk, Van Montagu, Marc, Kushnir, Sergei

Two novel homologous Arabidopsis proteins, DIP1 and DIP2, interact with the DNA‐binding domain of plant poly(ADP‐ribose) polymerase (PARP) in the yeast...

CEF, a Sec24 homologue of Arabidopsis thaliana, enhances the survival of yeast under oxidative stress conditions (2000)

Belles-Boix, Enric, Babiychuk, Elena, Montagu, Marc Van, Inzé, Dirk, Kushnir, Sergei

Budding yeast strains that produced the Arabidopsis thaliana protein CEF or its amino‐terminal proline‐rich domain were more tolerant to hydroperoxides. CEF is homologous to animal and...

Efficient gene tagging in Arabidopsis thaliana using a gene trap approach

Babiychuk, Elena, Fuangthong, Mayuree, Van Montagu, Marc, Inzé, Dirk, Kushnir, Sergei

Large quantities of DNA sequence information about plant genes are rapidly accumulating in public databases, but to progress from DNA sequence to biological function a mutant allele for each of the...

The Heat-Shock Element Is a Functional Component of the Arabidopsis APX1 Gene Promoter1

Storozhenko, Sergei, De Pauw, Pascal, Van Montagu, Marc, Inzé, Dirk, Kushnir, Sergei

Ascorbate peroxidases are important enzymes that detoxify hydrogen peroxide within the cytosol and chloroplasts of plant cells. To better understand their role in oxidative stress tolerance, the...

A Mutation of the Mitochondrial ABC Transporter Sta1 Leads to Dwarfism and Chlorosis in the Arabidopsis Mutant starik

Kushnir, Sergei, Babiychuk, Elena, Storozhenko, Sergei, Davey, Mark W., Papenbrock, Jutta, De Rycke, Riet, ...

A mutation in the Arabidopsis gene STARIK leads to dwarfism and chlorosis of plants with an altered morphology of leaf and cell nuclei. We show that the STARIK gene encodes the mitochondrial ABC...

Cytokinin Growth Responses in Arabidopsis Involve the 26S Proteasome Subunit RPN12

Smalle, Jan, Kurepa, Jasmina, Yang, Peizhen, Babiychuk, Elena, Kushnir, Sergei, Durski, Adam, ...

The 26S proteasome is an ATP-dependent eukaryotic protease responsible for degrading many important cell regulators, especially those conjugated with multiple ubiquitins. Bound on both ends of the...

γ-Glutamyl Transpeptidase in Transgenic Tobacco Plants. Cellular Localization, Processing, and Biochemical Properties1

Storozhenko, Sergei, Belles-Boix, Enric, Babiychuk, Elena, Hérouart, Didier, Davey, Mark W., Slooten, Luit, ...

γ-Glutamyl transpeptidase (γ-GT) is a ubiquitous enzyme that catalyzes the first step of glutathione (GSH) degradation in the γ-glutamyl cycle in mammals. A cDNA encoding an Arabidopsis homolog...

The Pleiotropic Role of the 26S Proteasome Subunit RPN10 in Arabidopsis Growth and Development Supports a Substrate-Specific Function in Abscisic Acid Signaling

Smalle, Jan, Kurepa, Jasmina, Yang, Peizhen, Emborg, Thomas J., Babiychuk, Elena, Kushnir, Sergei, ...

The 26S proteasome is an essential protease complex responsible for removing most short-lived intracellular proteins, especially those modified with polyubiquitin chains. We show here that an...

Iron-Regulated Expression of a Cytosolic Ascorbate Peroxidase Encoded by the APX1 Gene in Arabidopsis Seedlings

Fourcroy, Pierre, Vansuyt, Gérard, Kushnir, Sergei, Inzé, Dirk, Briat, Jean-François

Iron (Fe) is an essential element for living organisms. However, under aerobic conditions, its use is complicated because of its high insolubility and its potential toxicity through reactivity with...

Pigment Deficiency in Nightshade/Tobacco Cybrids Is Caused by the Failure to Edit the Plastid ATPase α-Subunit mRNAW⃞

Schmitz-Linneweber, Christian, Kushnir, Sergei, Babiychuk, Elena, Poltnigg, Peter, Herrmann, Reinhold G., Maier, Rainer M.

The subgenomes of the plant cell, the nuclear genome, the plastome, and the chondriome are known to interact through various types of coevolving macromolecules. The combination of the organellar...

Protection against Photooxidative Injury of Tobacco Leaves by 2-Alkenal Reductase. Detoxication of Lipid Peroxide-Derived Reactive Carbonyls1

Mano, Jun'ichi, Belles-Boix, Enric, Babiychuk, Elena, Inzé, Dirk, Torii, Yoshimitsu, Hiraoka, Eiji, ...

Degradation of lipid peroxides leads to the formation of cytotoxic 2-alkenals and oxenes (collectively designated reactive carbonyls). The novel NADPH-dependent oxidoreductase 2-alkenal reductase...

Efficient gene tagging in Arabidopsis thaliana using a gene trap approach

Babiychuk, Elena, Fuangthong, Mayuree, Van Montagu, Marc, Inzé, Dirk, Kushnir, Sergei

Large quantities of DNA sequence information about plant genes are rapidly accumulating in public databases, but to progress from DNA sequence to biological function a mutant allele for each of the...

The Heat-Shock Element Is a Functional Component of the Arabidopsis APX1 Gene Promoter1

Storozhenko, Sergei, De Pauw, Pascal, Van Montagu, Marc, Inzé, Dirk, Kushnir, Sergei

Ascorbate peroxidases are important enzymes that detoxify hydrogen peroxide within the cytosol and chloroplasts of plant cells. To better understand their role in oxidative stress tolerance, the...

A Mutation of the Mitochondrial ABC Transporter Sta1 Leads to Dwarfism and Chlorosis in the Arabidopsis Mutant starik

Kushnir, Sergei, Babiychuk, Elena, Storozhenko, Sergei, Davey, Mark W., Papenbrock, Jutta, De Rycke, Riet, ...

A mutation in the Arabidopsis gene STARIK leads to dwarfism and chlorosis of plants with an altered morphology of leaf and cell nuclei. We show that the STARIK gene encodes the mitochondrial ABC...

Cytokinin Growth Responses in Arabidopsis Involve the 26S Proteasome Subunit RPN12

Smalle, Jan, Kurepa, Jasmina, Yang, Peizhen, Babiychuk, Elena, Kushnir, Sergei, Durski, Adam, ...

The 26S proteasome is an ATP-dependent eukaryotic protease responsible for degrading many important cell regulators, especially those conjugated with multiple ubiquitins. Bound on both ends of the...

γ-Glutamyl Transpeptidase in Transgenic Tobacco Plants. Cellular Localization, Processing, and Biochemical Properties1

Storozhenko, Sergei, Belles-Boix, Enric, Babiychuk, Elena, Hérouart, Didier, Davey, Mark W., Slooten, Luit, ...

γ-Glutamyl transpeptidase (γ-GT) is a ubiquitous enzyme that catalyzes the first step of glutathione (GSH) degradation in the γ-glutamyl cycle in mammals. A cDNA encoding an Arabidopsis homolog...

The Pleiotropic Role of the 26S Proteasome Subunit RPN10 in Arabidopsis Growth and Development Supports a Substrate-Specific Function in Abscisic Acid Signaling

Smalle, Jan, Kurepa, Jasmina, Yang, Peizhen, Emborg, Thomas J., Babiychuk, Elena, Kushnir, Sergei, ...

The 26S proteasome is an essential protease complex responsible for removing most short-lived intracellular proteins, especially those modified with polyubiquitin chains. We show here that an...

Iron-Regulated Expression of a Cytosolic Ascorbate Peroxidase Encoded by the APX1 Gene in Arabidopsis Seedlings

Fourcroy, Pierre, Vansuyt, Gérard, Kushnir, Sergei, Inzé, Dirk, Briat, Jean-François

Iron (Fe) is an essential element for living organisms. However, under aerobic conditions, its use is complicated because of its high insolubility and its potential toxicity through reactivity with...

Pigment Deficiency in Nightshade/Tobacco Cybrids Is Caused by the Failure to Edit the Plastid ATPase α-Subunit mRNAW⃞

Schmitz-Linneweber, Christian, Kushnir, Sergei, Babiychuk, Elena, Poltnigg, Peter, Herrmann, Reinhold G., Maier, Rainer M.

The subgenomes of the plant cell, the nuclear genome, the plastome, and the chondriome are known to interact through various types of coevolving macromolecules. The combination of the organellar...

Protection against Photooxidative Injury of Tobacco Leaves by 2-Alkenal Reductase. Detoxication of Lipid Peroxide-Derived Reactive Carbonyls1

Mano, Jun'ichi, Belles-Boix, Enric, Babiychuk, Elena, Inzé, Dirk, Torii, Yoshimitsu, Hiraoka, Eiji, ...

Degradation of lipid peroxides leads to the formation of cytotoxic 2-alkenals and oxenes (collectively designated reactive carbonyls). The novel NADPH-dependent oxidoreductase 2-alkenal reductase...

AtATM3 Is Involved in Heavy Metal Resistance in Arabidopsis1

Kim, Do-Young, Bovet, Lucien, Kushnir, Sergei, Noh, Eun Woon, Martinoia, Enrico, Lee, Youngsook

AtATM3, an ATP-binding cassette transporter of Arabidopsis (Arabidopsis thaliana), is a mitochondrial protein involved in the biogenesis of iron-sulfur clusters and iron homeostasis in plants. Our...

Maintenance of plastid RNA editing activities independently of their target sites

Tillich, Michael, Poltnigg, Peter, Kushnir, Sergei, Schmitz-Linneweber, Christian

RNA editing in plant organelles is mediated by site-specific, nuclear-encoded factors. Previous data suggested that the maintenance of these factors depends on the presence of their rapidly evolving...

Allelic mutant series reveal distinct functions for Arabidopsis cycloartenol synthase 1 in cell viability and plastid biogenesis

Babiychuk, Elena, Bouvier-Navé, Pierrette, Compagnon, Vincent, Suzuki, Masashi, Muranaka, Toshiya, Van Montagu, Marc, ...

Sterols have multiple functions in all eukaryotes. In plants, sterol biosynthesis is initiated by the enzymatic conversion of 2,3-oxidosqualene to cycloartenol. This reaction is catalyzed by...

Albinism and cell viability in cycloartenol synthase deficient Arabidopsis

Babiychuk, Elena, Bouvier-Navé, Pierrette, Compagnon, Vincent, Suzuki, Masashi, Muranaka, Toshiya, Van Montagu, Marc, ...

Phenotypes of Arabidopsis thaliana that carry mutations in CYCLOARTENOL SYNTHASE 1 (CAS1) which is required in sterol biosynthesis have been described. Knockout mutant alleles are responsible of a...