Sergio DJ Pena

Update of the gene discovery program in Schistosoma mansoni with the expressed sequence tag approach (1997)

Elida ML Rabelo, Gloria R Franco, Vasco AC Azevedo, Heloisa B Pena, Tulio M Santos, Wendell SF Meira, ...

Continuing the Schistosoma mansoni Genome Project 363 new templates were sequenced generating 205 more ESTs corresponding to 91 genes. Seventy four of these genes (81%) had not previously been...

Evidentiation of Paramyosin (Sm-97) as a modulating antigen on granulomatous hypersensitivity to Schistosoma mansoni eggs (1997)

Cristine Hirsch, Claudia Carvalho-Queiroz, Gloria R Franco, Sergio DJ Pena, Andrew JG Simpson, Alfredo M Goes

A Schistosoma mansoni adult worm anionic fraction (PIII) has previously been shown to protect mice against challenge infection and to reduce pulmonary and hepatic granulomatous hypersensitivity....

DNA Polymorphism of Schistosomes and their Snail Hosts (1995)

Andrew JG Simpson, Emmanuel Dias Neto, Teofania Hda Vidigal, Heloisa B Pena, Omar S Carvalho, Sergio DJ Pena

Analysis of the genomes of schistosomes and one of their intermediate hosts, Biomphalaria glabrata, using Random Amplified Polymorphic DNA (RAPD) demonstrated that intraspecific genetic polymorphism...

Sequencing and Identification of Expressed Schistosoma mansoni   Genes by Random Selection of cDNA Clones from a Directional Library (1995)

Gloria R Franco, Andrew JG Simpson, Sergio DJ Pena

We have initiated a gene discovery program in Schistosoma mansoni   based on the technique of Expressed Sequence Tags (ESTs), i.e. partial sequences of cDNAs obtained from single passes in automatic...