Pannekoek, Yvonne, Morelli, Giovanna, Kusecek, Barica, Morré, Servaas A, Ossewaarde, Jacobus M, Langerak, Ankie A, ...
Abstract Background The obligate intracellular growing bacterium Chlamydia trachomatis causes diseases like trachoma, urogenital infection and lymphogranuloma venereum with severe morbidity. Several...
Den Hartog, Janneke E, Ouburg, Sander, Land, Jolande A, Lyons, Joseph M, Ito, James I, Peña, A Salvador, ...
Abstract Background In women, Chlamydia (C.) trachomatis upper genital tract infection can cause distal tubal damage and occlusion, increasing the risk of tubal factor subfertility and ectopic...
Joseph M. Lyons, James I. Ito, Servaas A. Morré
Objective. The aim of this study was to determine if vaginal application of the immune response modifier imiquimod (Aldara cream, 3M Pharmaceuticals, St Paul, Minn) would alter the course and/or...
Joseph M. Lyons, James I. Ito, Servaas A. Morré
Objective. The aim of this study was to determine if vaginal application of the immune response modifier imiquimod (Aldara cream, 3M Pharmaceuticals, St Paul, Minn) would alter the course and/or...
Ouburg, Sander, Spaargaren, Joke, Den Hartog, Janneke E, Land, Jolande A, Fennema, Johan SA, Pleijster, Jolein, ...
Abstract Background The functional polymorphism -260 C>T in the LPS sensing TLR4 co-receptor CD14 gene enhances the transcriptional activity and results in a higher CD14 receptor density. Individuals...
Lyons, Joseph M, Morré, Servaas A, Airo-Brown, Lucy P, Peña, A Salvador, Ito, James I
Abstract Background Chlamydia trachomatis is the most common sexually transmitted bacterial pathogen causing female genital tract infection throughout the world. Reinfection with the same serovar, as...
Hoang, Thi Q T, De Vos, Liselotte, Verminnen, Kristel, Harkinezhad, Taher, Chiers, Koen, ...
The purpose of the present study was to evaluate pigs as a large-animal model for female genital infection with two Chlamydia trachomatis human serovar E strains. Sixteen-week-old...
Van Valkengoed, Irene GM, Morré, Servaas A, Van Den Brule, Adriaan JC, Meijer, Chris JLM, Bouter, Lex M, Boeke, A Joan P
Background Cost-effectiveness analyses of screening programmes for asymptomatic Chlamydia trachomatis infection suggest that screening at low prevalences in the population is cost-effective. However,...
Murillo, Laura S., Land, Jolande A., Pleijster, Jolein, Bruggeman, Cathrien A., Peña, A. Salvador, Morré, Servaas A.
BACKGROUND: Chlamydia trachomatis infections have been associated with tubal pathology. However, not all C.trachomatis‐infected women actually develop tubal pathology. Recently, host genetic...
Morré, Servaas A., Moes, Robert M., Boeke, A. Joan P.
This study determined the performances of the LCx (Abbott) and COBAS Amplicor (Roche) tests with urine specimens for the detection of Chlamydia trachomatis in an asymptomatic screening population....
Morré, Servaas A., Munk, Christian, Krüger-Kjaer, Susanne, Winther, Jeanette F., Jørgensens, Hans O., ...
Pooling, in groups of five, of urine specimens from asymptomatically infected men in a population with 4% prevalence, as determined by case finding, is 100% sensitive and specific and results in a...
Morré, Servaas A., Ossewaarde, Jacobus M., Savelkoul, Paul H. M., Stoof, Jeroen
Amplified fragment length polymorphism (AFLP) fingerprinting of clinical isolates of Chlamydia trachomatis serovars D, E, and F showed a low percentage of genetic heterogeneity, but clear differences...
Morré, Servaas A., De Jong, Afke, Boeke, A. Joan P., ...
The use of mailed, home-obtained urine specimens could facilitate screening programs for the detection of asymptomatic Chlamydia trachomatis infections. Since transport time could have an adverse...
Pannekoek, Yvonne, Van Der Ende, Arie, Eijk, Paul P., Van Marle, Jan, De Witte, Moniek A., Ossewaarde, Jacobus M., ...
To investigate the correlation between the incA I47T mutation in Chlamydia trachomatis and the nonfusogenic phenotype, the incA genes of 25 isolates were sequenced. Four major sequence types were...
Meijer, Adam, Morré, Servaas A., Savelkoul, Paul H. M., Ossewaarde, Jacobus M.
The genomic relatedness of 19 Chlamydia pneumoniae isolates (17 from respiratory origin and 2 from atherosclerotic origin), 21 Chlamydia trachomatis isolates (all serovars from the human biovar, an...
Morré, Servaas A., Ossewaarde, Jacobus M., Lan, Jar, Walboomers, Jan M. M., MacLaren, David M., ...
Urogenital isolates (n = 93) of Chlamydia trachomatis were differentiated into serovars and variants by serotyping with monoclonal antibodies and genotyping by restriction fragment length...
Genotyping of Chlamydia trachomatis in Urine Specimens Will Facilitate Large Epidemiological Studies
Morré, Servaas A., Moes, Robert, Van Valkengoed, Irene, Boeke, Joan P., ...
The serovars of Chlamydia trachomatis-positive urine specimens (n = 81; as detected by PCR and ligase chain reaction) were successfully analyzed in 94% of cases by omp1 PCR-based RFLP analysis. The...
Morré, Servaas A., Munk, Christian, Persson, Kenneth, Krüger-Kjaer, Susanne, Van Dijk, Rogier, ...
Three commercially available, peptide-based enzyme-linked immunosorbent assay (ELISA) systems (Chlamydia trachomatis IgG and IgA EIA [CT-EIA; Labsystems OY, Helsinki, Finland], SeroCT IgG and IgA...
Molano, Monica, Morré, Servaas A., Pol, Rene
In this study we developed and evaluated a new PCR-based typing assay, directed to the VD2 region of the omp1 gene, for the detection and typing of urogenital Chlamydia trachomatis infections. A...
Pannekoek, Yvonne, Spaargaren, Joke, Langerak, Ankie A. J., Merks, Judith, Morré, Servaas A., Van Der Ende, Arie
IncA variation among Dutch Chlamydia trachomatis isolates was investigated. Of 98 strains, two carried an incA with a premature stop codon, lacked IncA, and were nonfusogenic, while 96 contained an...
Specific-Pathogen-Free Pigs as an Animal Model for Studying Chlamydia trachomatis Genital Infection
Vanrompay, Daisy, Hoang, Thi Q. T., De Vos, Liselotte, Verminnen, Kristel, Harkinezhad, Taher, Chiers, Koen, ...
The purpose of the present study was to evaluate pigs as a large-animal model for female genital infection with two Chlamydia trachomatis human serovar E strains. Sixteen-week-old...
Ouburg, Sander, Spaargaren, Joke, Den Hartog, Janneke E, Land, Jolande A, Fennema, Johan SA, Pleijster, Jolein, ...
Morré, Servaas A, Bouter, Lex M, ...
BACKGROUND: Adequate treatment and follow-up of patients is essential to the success of a screening programme for Chlamydia trachomatis. There has been a lack of data on follow-up, confirmation of...
Partner notification among asymptomatic Chlamydia trachomatis cases, by means of mailed specimens.
Morré, Servaas A, Bouter, Lex M, ...
The objective of the study was to evaluate the prevalence of Chlamydia trachomatis infection and the participation, among partners of asymptomatic cases in general practice. Index cases were...
Den Hartog, Janneke E, Ouburg, Sander, Land, Jolande A, Lyons, Joseph M, Ito, James I, Peña, A Salvador, ...
Lyons, Joseph M., Ito, James I., Morré, Servaas A.
Objective. The aim of this study was to determine if vaginal application of the immune response modifier imiquimod (Aldara cream, 3M Pharmaceuticals, St Paul, Minn) would alter the course and/or...
Morré, Servaas A., Moes, Robert M., Boeke, A. Joan P.
This study determined the performances of the LCx (Abbott) and COBAS Amplicor (Roche) tests with urine specimens for the detection of Chlamydia trachomatis in an asymptomatic screening population....
Morré, Servaas A., Munk, Christian, Krüger-Kjaer, Susanne, Winther, Jeanette F., Jørgensens, Hans O., ...
Pooling, in groups of five, of urine specimens from asymptomatically infected men in a population with 4% prevalence, as determined by case finding, is 100% sensitive and specific and results in a...
Morré, Servaas A., Ossewaarde, Jacobus M., Savelkoul, Paul H. M., Stoof, Jeroen
Amplified fragment length polymorphism (AFLP) fingerprinting of clinical isolates of Chlamydia trachomatis serovars D, E, and F showed a low percentage of genetic heterogeneity, but clear differences...
Morré, Servaas A., De Jong, Afke, Boeke, A. Joan P., ...
The use of mailed, home-obtained urine specimens could facilitate screening programs for the detection of asymptomatic Chlamydia trachomatis infections. Since transport time could have an adverse...
Pannekoek, Yvonne, Van Der Ende, Arie, Eijk, Paul P., Van Marle, Jan, De Witte, Moniek A., Ossewaarde, Jacobus M., ...
To investigate the correlation between the incA I47T mutation in Chlamydia trachomatis and the nonfusogenic phenotype, the incA genes of 25 isolates were sequenced. Four major sequence types were...
Meijer, Adam, Morré, Servaas A., Savelkoul, Paul H. M., Ossewaarde, Jacobus M.
The genomic relatedness of 19 Chlamydia pneumoniae isolates (17 from respiratory origin and 2 from atherosclerotic origin), 21 Chlamydia trachomatis isolates (all serovars from the human biovar, an...
Morré, Servaas A., Ossewaarde, Jacobus M., Lan, Jar, Walboomers, Jan M. M., MacLaren, David M., ...
Urogenital isolates (n = 93) of Chlamydia trachomatis were differentiated into serovars and variants by serotyping with monoclonal antibodies and genotyping by restriction fragment length...
Genotyping of Chlamydia trachomatis in Urine Specimens Will Facilitate Large Epidemiological Studies
Morré, Servaas A., Moes, Robert, Van Valkengoed, Irene, Boeke, Joan P., ...
The serovars of Chlamydia trachomatis-positive urine specimens (n = 81; as detected by PCR and ligase chain reaction) were successfully analyzed in 94% of cases by omp1 PCR-based RFLP analysis. The...
Morré, Servaas A., Munk, Christian, Persson, Kenneth, Krüger-Kjaer, Susanne, Van Dijk, Rogier, ...
Three commercially available, peptide-based enzyme-linked immunosorbent assay (ELISA) systems (Chlamydia trachomatis IgG and IgA EIA [CT-EIA; Labsystems OY, Helsinki, Finland], SeroCT IgG and IgA...
Molano, Monica, Morré, Servaas A., Pol, Rene
In this study we developed and evaluated a new PCR-based typing assay, directed to the VD2 region of the omp1 gene, for the detection and typing of urogenital Chlamydia trachomatis infections. A...
Pannekoek, Yvonne, Spaargaren, Joke, Langerak, Ankie A. J., Merks, Judith, Morré, Servaas A., Van Der Ende, Arie
IncA variation among Dutch Chlamydia trachomatis isolates was investigated. Of 98 strains, two carried an incA with a premature stop codon, lacked IncA, and were nonfusogenic, while 96 contained an...
Specific-Pathogen-Free Pigs as an Animal Model for Studying Chlamydia trachomatis Genital Infection
Vanrompay, Daisy, Hoang, Thi Q. T., De Vos, Liselotte, Verminnen, Kristel, Harkinezhad, Taher, Chiers, Koen, ...
The purpose of the present study was to evaluate pigs as a large-animal model for female genital infection with two Chlamydia trachomatis human serovar E strains. Sixteen-week-old...
Morré, Servaas A, Bouter, Lex M, ...
BACKGROUND: Adequate treatment and follow-up of patients is essential to the success of a screening programme for Chlamydia trachomatis. There has been a lack of data on follow-up, confirmation of...
Partner notification among asymptomatic Chlamydia trachomatis cases, by means of mailed specimens.
Morré, Servaas A, Bouter, Lex M, ...
The objective of the study was to evaluate the prevalence of Chlamydia trachomatis infection and the participation, among partners of asymptomatic cases in general practice. Index cases were...
Ouburg, Sander, Spaargaren, Joke, Den Hartog, Janneke E, Land, Jolande A, Fennema, Johan SA, Pleijster, Jolein, ...
Den Hartog, Janneke E, Ouburg, Sander, Land, Jolande A, Lyons, Joseph M, Ito, James I, Peña, A Salvador, ...
Lyons, Joseph M., Ito, James I., Morré, Servaas A.
Objective. The aim of this study was to determine if vaginal application of the immune response modifier imiquimod (Aldara cream, 3M Pharmaceuticals, St Paul, Minn) would alter the course and/or...