Shannon McKinney-Freeman

Derivation of Hematopoietic Stem Cells from Murine Embryonic Stem Cells

McKinney-Freeman, Shannon, Daley, George

A stem cell is defined as a cell with the capacity to both self-renew and generate multiple differentiated progeny. Embryonic stem cells (ESC) are derived from the blastocyst of the early embryo and...

Cdx gene deficiency compromises embryonic hematopoiesis in the mouse

Wang, Yuan, Yabuuchi, Akiko, McKinney-Freeman, Shannon, Ducharme, Danica M. K., Ray, Manas K., Chawengsaksophak, Kallayanee, ...

Cdx genes (Cdx1, Cdx2, and Cdx4) encode a family of caudal-related transcription factors that mediate anterior–posterior patterning during embryogenesis through Hox gene regulation. Homologues in...