Inhibition of ebselen on aflatoxin B1-induced hepatocarcinogenesis in Fischer 344 rats (2000)
Yang, Cheng-Feng, Liu, Jin, Wasser, Shanthi, Shen, Han-Ming, Tan, Carolyn Eng-Looi, Ong, Choon-Nam
Aflatoxin B1 (AFB1), a potent hepatocarcinogen, enhances ROS formation and causes oxidative DNA damage, which may play a role in its carcinogenicity. We have demonstrated recently that ebselen, an...
The Level of Viral Antigen Presented by Hepatocytes Influences CD8 T-Cell Functionâ–ż
Gehring, Adam J., Sun, Dianxing, Kennedy, Patrick T. F., Lim, Seng Gee, Wasser, Shanthi, ...
CD8 T cells exert their antiviral function through cytokines and lysis of infected cells. Because hepatocytes are susceptible to noncytolytic mechanisms of viral clearance, CD8 T-cell antiviral...