Shaun Mahony

Combined analysis reveals a core set of cycling genes (2007)

Lu, Yong, Mahony, Shaun, Benos, Panayiotis V, Rosenfeld, Roni, Simon, Itamar, Breeden, Linda L, ...

Abstract Background Global transcript levels throughout the cell cycle have been characterized using microarrays in several species. Early analysis of these experiments focused on individual species....

Regulatory conservation of protein coding and microRNA genes in vertebrates: lessons from the opossum genome (2007)

Mahony, Shaun, Corcoran, David L, Feingold, Eleanor, Benos, Panayiotis V

Abstract Background Being the first noneutherian mammal sequenced, Monodelphis domestica (opossum) offers great potential for enhancing our understanding of the evolutionary processes that take place...

DNA Familial Binding Profiles Made Easy: Comparison of Various Motif Alignment and Clustering Strategies (2007)

Shaun Mahony, Philip E. Auron, Panayiotis V. Benos

Transcription factor (TF) proteins recognize a small number of DNA sequences with high specificity and control the expression of neighbouring genes. The evolution of TF binding preference has been...

DNA Familial Binding Profiles Made Easy: Comparison of Various Motif Alignment and Clustering Strategies (2007)

Shaun Mahony, Philip Auron, Panayiotis (Takis) V. Benos

Transcription factor (TF) proteins recognize a small number of DNA sequences with high specificity and control the expression of neighbouring genes. The evolution of TF binding preference has been...

Reconstructing an Ancestral Mammalian Immune Supercomplex from a Marsupial Major Histocompatibility Complex (2006)

Katherine Belov, Janine E. Deakin, Anthony T. Papenfuss, Michelle L. Baker, Sandra D. Melman, Hannah V. Siddle, ...

Opossum genomic sequence data permit researchers to fill gaps in our knowledge of how the Major Histocompatibility Complex evolved within the mammalian lineage.

Reconstructing an Ancestral Mammalian Immune Supercomplex from a Marsupial Major Histocompatibility Complex (2006)

Katherine Belov, Janine E. Deakin, Anthony T. Papenfuss, Michelle L. Baker, Sandra D. Melman, Hannah V. Siddle, ...

The first sequenced marsupial genome promises to reveal unparalleled insights into mammalian evolution. We have used the Monodelphis domestica (gray short-tailed opossum) sequence to construct the...

Gene prediction using the Self-Organizing Map: automatic generation of multiple gene models (2004)

Mahony, Shaun, McInerney, James O, Smith, Terry J, Golden, Aaron

Abstract Background Many current gene prediction methods use only one model to represent protein-coding regions in a genome, and so are less likely to predict the location of genes that have an...

Gene prediction using the Self-Organizing Map: automatic generation of multiple gene models (2004)

Mahony, Shaun, McInerney, James O, Smith, Terry J, Golden, Aaron

Background: Many current gene prediction methods use only one model to represent proteincoding regions in a genome, and so are less likely to predict the location of genes that have an atypical...

Reconstructing an Ancestral Mammalian Immune Supercomplex from a Marsupial Major Histocompatibility Complex

Belov, Katherine, Deakin, Janine E, Papenfuss, Anthony T, Baker, Michelle L, Melman, Sandra D, Siddle, Hannah V, ...

The first sequenced marsupial genome promises to reveal unparalleled insights into mammalian evolution. We have used theMonodelphis domestica (gray short-tailed opossum) sequence to construct the...

Reconstructing an Ancestral Mammalian Immune Supercomplex from a Marsupial Major Histocompatibility Complex

Belov, Katherine, Deakin, Janine E, Papenfuss, Anthony T, Baker, Michelle L, Melman, Sandra D, Siddle, Hannah V, ...

The first sequenced marsupial genome promises to reveal unparalleled insights into mammalian evolution. We have used theMonodelphis domestica (gray short-tailed opossum) sequence to construct the...

DNA Familial Binding Profiles Made Easy: Comparison of Various Motif Alignment and Clustering Strategies

Mahony, Shaun, Auron, Philip E, Benos, Panayiotis V

Transcription factor (TF) proteins recognize a small number of DNA sequences with high specificity and control the expression of neighbouring genes. The evolution of TF binding preference has been...

Regulatory conservation of protein coding and microRNA genes in vertebrates: lessons from the opossum genome

Mahony, Shaun, Corcoran, David L, Feingold, Eleanor, Benos, Panayiotis V

A study of conservation of non-coding sequences, cis-regulatory elements and biological functions of regulated genes in opossum and other vertebrates enables better estimation of promoter...

STAMP: a web tool for exploring DNA-binding motif similarities

Mahony, Shaun, Benos, Panayiotis V.

STAMP is a newly developed web server that is designed to support the study of DNA-binding motifs. STAMP may be used to query motifs against databases of known motifs; the software aligns input...

ORegAnno: an open-access community-driven resource for regulatory annotation

Griffith, Obi L., Montgomery, Stephen B., Bernier, Bridget, Chu, Bryan, Kasaian, Katayoon, Aerts, Stein, ...

ORegAnno is an open-source, open-access database and literature curation system for community-based annotation of experimentally identified DNA regulatory regions, transcription factor binding sites...

Combined analysis reveals a core set of cycling genes

Lu, Yong, Mahony, Shaun, Benos, Panayiotis V, Rosenfeld, Roni, Simon, Itamar, Breeden, Linda L, ...

The simultaneous analysis of expression data from multiple species reveals a core set of conserved cycling genes that is much larger than previously thought.