Noguchi, Eishi, Saitoh, Yoh-hei, Sazer, Shelley, Nishimoto, Takeharu
Disruption of the YRB2 gene encoding a nuclear Ran-binding protein homologous to Yrb1p/RanBP1 makes Saccharomyces cerevisiae cold sensitive for colony-formation, but not for growth in liquid...
Transcriptional control of the mouse dihydrofolate reductase gene / (1987)
Thesis (Ph. D.)--Stanford University, 1988.
He, Xiangwei, Patterson, Thomas E., Sazer, Shelley
The spindle checkpoint monitors mitotic spindle integrity and the attachment of kinetochores to the spindle. Upon sensing a defect the checkpoint blocks cell cycle progression and thereby prevents...
Patterson, Thomas E., Albrecht, Elizabeth B., Nurse, Paul, Sazer, Shelley, Stark, George R.
The Schizosaccharomyces pombe sod2 gene, located near the telomere on the long arm of chromosome I, encodes a Na+ (or Li+)/H+ antiporter. Amplification of sod2 has previously been shown to confer...
Redundant control of rereplication in fission yeast
Gopalakrishnan, Vidya, Simancek, Pamela, Houchens, Christopher, Snaith, Hilary A., Frattini, Mark G., Sazer, Shelley, ...
The initiation of DNA replication at replication origins in eukaryotic cells is tightly controlled to ensure that the genome is duplicated only once each cell cycle. We present evidence that in...
Dimitrov, Krassen, Sazer, Shelley
Most microorganisms live in conditions of nutrient limitation in their natural habitats. When exposed to these conditions they respond with physiological and morphological changes that enable them to...
Salus, Sandra S., Demeter, Janos, Sazer, Shelley
Misregulation of the evolutionarily conserved GTPase Ran in fission yeast results in defects in several cellular processes in cells that are competent for nucleocytoplasmic protein transport. These...
HIV-1 Vpr Induces Defects in Mitosis, Cytokinesis, Nuclear Structure, and Centrosomes
Chang, Fred, Re, Fabio, Sebastian, Sarah, Sazer, Shelley, Luban, Jeremy
Human immunodeficiency virus type 1 (HIV-1) Vpr is a 15-kDa accessory protein that contributes to several steps in the viral replication cycle and promotes virus-associated pathology. Previous...
Baï, Siau Wei, Rouquette, Jacques, Umeda, Makoto, Faigle, Wolfgang, Loew, Damarys, Sazer, Shelley, ...
We have characterized Schizosaccharomyces pombe open reading frames encoding potential orthologues of constituents of the evolutionarily conserved Saccharomyces cerevisiae Nup84 vertebrate Nup107-160...
Kadura, Sheila, He, Xiangwei, Vanoosthuyse, Vincent, Hardwick, Kevin G., Sazer, Shelley
During mitosis, the spindle assembly checkpoint (SAC) responds to faulty attachments between kinetochores and the mitotic spindle by imposing a metaphase arrest until the defect is corrected, thereby...
Umeda, Makoto, Izaddoost, Shahed, Cushman, Ian, Moore, Mary Shannon, Sazer, Shelley
The nuclear import of classical nuclear localization signal-containing proteins depends on importin-α transport receptors. In budding yeast there is a single importin-α gene and in higher...
He, Xiangwei, Patterson, Thomas E., Sazer, Shelley
The spindle checkpoint monitors mitotic spindle integrity and the attachment of kinetochores to the spindle. Upon sensing a defect the checkpoint blocks cell cycle progression and thereby prevents...
Patterson, Thomas E., Albrecht, Elizabeth B., Nurse, Paul, Sazer, Shelley, Stark, George R.
The Schizosaccharomyces pombe sod2 gene, located near the telomere on the long arm of chromosome I, encodes a Na+ (or Li+)/H+ antiporter. Amplification of sod2 has previously been shown to confer...
Redundant control of rereplication in fission yeast
Gopalakrishnan, Vidya, Simancek, Pamela, Houchens, Christopher, Snaith, Hilary A., Frattini, Mark G., Sazer, Shelley, ...
The initiation of DNA replication at replication origins in eukaryotic cells is tightly controlled to ensure that the genome is duplicated only once each cell cycle. We present evidence that in...
Dimitrov, Krassen, Sazer, Shelley
Most microorganisms live in conditions of nutrient limitation in their natural habitats. When exposed to these conditions they respond with physiological and morphological changes that enable them to...
Salus, Sandra S., Demeter, Janos, Sazer, Shelley
Misregulation of the evolutionarily conserved GTPase Ran in fission yeast results in defects in several cellular processes in cells that are competent for nucleocytoplasmic protein transport. These...
HIV-1 Vpr Induces Defects in Mitosis, Cytokinesis, Nuclear Structure, and Centrosomes
Chang, Fred, Re, Fabio, Sebastian, Sarah, Sazer, Shelley, Luban, Jeremy
Human immunodeficiency virus type 1 (HIV-1) Vpr is a 15-kDa accessory protein that contributes to several steps in the viral replication cycle and promotes virus-associated pathology. Previous...
Baï, Siau Wei, Rouquette, Jacques, Umeda, Makoto, Faigle, Wolfgang, Loew, Damarys, Sazer, Shelley, ...
We have characterized Schizosaccharomyces pombe open reading frames encoding potential orthologues of constituents of the evolutionarily conserved Saccharomyces cerevisiae Nup84 vertebrate Nup107-160...
Kadura, Sheila, He, Xiangwei, Vanoosthuyse, Vincent, Hardwick, Kevin G., Sazer, Shelley
During mitosis, the spindle assembly checkpoint (SAC) responds to faulty attachments between kinetochores and the mitotic spindle by imposing a metaphase arrest until the defect is corrected, thereby...
Umeda, Makoto, Izaddoost, Shahed, Cushman, Ian, Moore, Mary Shannon, Sazer, Shelley
The nuclear import of classical nuclear localization signal-containing proteins depends on importin-α transport receptors. In budding yeast there is a single importin-α gene and in higher...
Vesicle-Like Biomechanics Governs Important Aspects of Nuclear Geometry in Fission Yeast
Lim H. W., Gerald, Huber, Greg, Torii, Yoshihiro, Hirata, Aiko, Miller, Jonathan, Sazer, Shelley
It has long been known that during the closed mitosis of many unicellular eukaryotes, including the fission yeast (Schizosaccharomyces pombe), the nuclear envelope remains intact while the nucleus...
imp2, a New Component of the Actin Ring in the Fission Yeast Schizosaccharomyces pombe
Demeter, Janos, Sazer, Shelley
Cytokinesis is the part of the cell cycle in which the cell is cleaved to form two daughter cells. The unicellular yeast, Schizosaccharomyces pombe is an excellent model organism in which to study...
The Fission Yeast Ran Gtpase Is Required for Microtubule Integrity
Fleig, Ursula, Salus, Sandra S., Karig, Inga, Sazer, Shelley
The microtubule cytoskeleton plays a pivotal role in cytoplasmic organization, cell division, and the correct transmission of genetic information. In a screen designed to identify fission yeast genes...