Shernaz X. Bamji

Semaphorin 5B mediates synapse elimination in hippocampal neurons (2009)

O'Connor, Timothy P, Cockburn, Katie, Wang, Wenyan, Tapia, Lucia, Currie, Erin, Bamji, Shernaz X

Abstract Background Semaphorins are known to play an important role in axon guidance and growth by triggering dynamic rearrangements of the actin cytoskeleton in the neuronal growth cone....

BDNF mobilizes synaptic vesicles and enhances synapse formation by disrupting cadherin–β-catenin interactions

Bamji, Shernaz X., Rico, Beatriz, Kimes, Nikole, Reichardt, Louis F.

Neurons of the vertebrate central nervous system have the capacity to modify synapse number, morphology, and efficacy in response to activity. Some of these functions can be attributed to...

P53 Is Essential for Developmental Neuron Death as Regulated by the TrkA and p75 Neurotrophin Receptors

Aloyz, Raquel S., Bamji, Shernaz X., Pozniak, Christine D., Toma, Jean G., Atwal, Jasvinder, Kaplan, David R., ...

Naturally occurring sympathetic neuron death is the result of two apoptotic signaling events: one normally suppressed by NGF/TrkA survival signals, and a second activated by the p75 neurotrophin...

The p75 Neurotrophin Receptor Mediates Neuronal Apoptosis and Is Essential for Naturally Occurring Sympathetic Neuron Death

Bamji, Shernaz X., Majdan, Marta, Pozniak, Christine D., Belliveau, Daniel J., Aloyz, Raquel, Kohn, Judi, ...

Abstract. To determine whether the p75 neurotrophin receptor (p75NTR) plays a role in naturally occurring neuronal death, we examined neonatal sympathetic neurons that express both the TrkA tyrosine...

Synapses are regulated by the cytoplasmic tyrosine kinase Fer in a pathway mediated by p120catenin, Fer, SHP-2, and β-catenin

Lee, Seung-Hye, Peng, I.-Feng, Ng, Yu Gie, Yanagisawa, Masahiro, Bamji, Shernaz X., Elia, Lisa P., ...

Localization of presynaptic components to synaptic sites is critical for hippocampal synapse formation. Cell adhesion–regulated signaling is important for synaptic development and function, but...

Semaphorin 5B mediates synapse elimination in hippocampal neurons

O'Connor, Timothy P, Cockburn, Katie, Wang, Wenyan, Tapia, Lucia, Currie, Erin, Bamji, Shernaz X

Scribble Interacts with β-Catenin to Localize Synaptic Vesicles to Synapses

Sun, Yu, Aiga, Mytyl, Yoshida, Eileen, Humbert, Patrick O., Bamji, Shernaz X.

An understanding of how synaptic vesicles are recruited to and maintained at presynaptic compartments is required to discern the molecular mechanisms underlying presynaptic assembly and plasticity....