Sheshagiri Gaonkar

Pharmacokinetics-Pharmacodynamics of Rifampin in an Aerosol Infection Model of Tuberculosis

Jayaram, Ramesh, Gaonkar, Sheshagiri, Kaur, Parvinder, Suresh, B. L., Mahesh, B. N., Jayashree, R., ...

Limited information exists on the pharmacokinetic (PK)-pharmacodynamic (PD) relationships of drugs against Mycobacterium tuberculosis. Our aim was to identify the PK-PD parameter that best describes...

Isoniazid Pharmacokinetics-Pharmacodynamics in an Aerosol Infection Model of Tuberculosis

Jayaram, Ramesh, Shandil, Radha. K., Gaonkar, Sheshagiri, Kaur, Parvinder, Suresh, B. L., Mahesh, B. N., ...

Limited data exist on the pharmacokinetic-pharmacodynamic (PK-PD) parameters of the bactericidal activities of the available antimycobacterial drugs. We report on the PK-PD relationships for...

Pharmacokinetics-Pharmacodynamics of Rifampin in an Aerosol Infection Model of Tuberculosis

Jayaram, Ramesh, Gaonkar, Sheshagiri, Kaur, Parvinder, Suresh, B. L., Mahesh, B. N., Jayashree, R., ...

Limited information exists on the pharmacokinetic (PK)-pharmacodynamic (PD) relationships of drugs against Mycobacterium tuberculosis. Our aim was to identify the PK-PD parameter that best describes...

Isoniazid Pharmacokinetics-Pharmacodynamics in an Aerosol Infection Model of Tuberculosis

Jayaram, Ramesh, Shandil, Radha. K., Gaonkar, Sheshagiri, Kaur, Parvinder, Suresh, B. L., Mahesh, B. N., ...

Limited data exist on the pharmacokinetic-pharmacodynamic (PK-PD) parameters of the bactericidal activities of the available antimycobacterial drugs. We report on the PK-PD relationships for...

Moxifloxacin, Ofloxacin, Sparfloxacin, and Ciprofloxacin against Mycobacterium tuberculosis: Evaluation of In Vitro and Pharmacodynamic Indices That Best Predict In Vivo Efficacyâ–¿

Shandil, Radha K., Jayaram, Ramesh, Kaur, Parvinder, Gaonkar, Sheshagiri, Suresh, B. L., Mahesh, B. N., ...

Members of the fluoroquinolone class are being actively evaluated for inclusion in tuberculosis chemotherapy regimens, and we sought to determine the best in vitro and pharmacodynamic predictors of...