Hori, Osamu, Yan, Shi Du, Ogawa, Satoshi, Kuwabara, Keisuke, Matsumoto, Masayasu, Stern, David, ...
Proteins or lipids exposed to aldose sugars undergo initial and ultimately irreversible modification resulting in the formation of so-called advanced glycation end-products (AGEs). AGEs are...
Central role of RAGE-dependent neointimal expansion in arterial restenosis
Sakaguchi, Taichi, Yan, Shi Fang, Yan, Shi Du, Belov, Dmitri, Rong, Ling Ling, Sousa, Monica, ...
Cellular proliferation, migration, and expression of extracellular matrix proteins and MMPs contribute to neointimal formation upon vascular injury. Wild-type mice undergoing arterial endothelial...
The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses
Schmidt, Ann Marie, Yan, Shi Du, Yan, Shi Fang, Stern, David M.
Liliensiek, Birgit, Weigand, Markus A., Bierhaus, Angelika, Nicklas, Werner, Kasper, Michael, Hofer, Stefan, ...
While the initiation of the adaptive and innate immune response is well understood, less is known about cellular mechanisms propagating inflammation. The receptor for advanced glycation end products...
RAGE and amyloid beta interactions: Atomic force microscopy and molecular modeling
Chaney, Michael O., Stine, W. Blaine, Kokjohn, Tyler A., Kuo, Yu-Min, Esh, Chera, Rahman, Afroza, ...
In the AD brain, there are elevated amounts of soluble and insoluble Aβ peptides which enhance the expression of membrane bound and soluble receptor for advanced glycation end products (RAGE). The...
Central role of RAGE-dependent neointimal expansion in arterial restenosis
Sakaguchi, Taichi, Yan, Shi Fang, Yan, Shi Du, Belov, Dmitri, Rong, Ling Ling, Sousa, Monica, ...
Cellular proliferation, migration, and expression of extracellular matrix proteins and MMPs contribute to neointimal formation upon vascular injury. Wild-type mice undergoing arterial endothelial...
The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses
Schmidt, Ann Marie, Yan, Shi Du, Yan, Shi Fang, Stern, David M.
Liliensiek, Birgit, Weigand, Markus A., Bierhaus, Angelika, Nicklas, Werner, Kasper, Michael, Hofer, Stefan, ...
While the initiation of the adaptive and innate immune response is well understood, less is known about cellular mechanisms propagating inflammation. The receptor for advanced glycation end products...
Cellular Cofactors for Amyloid β-Peptide-Induced Cell Stress : Moving from Cell Culture to in Vivo
Yan, Shi Du, Roher, Alex, Schmidt, Ann Marie, Stern, David M.
Expression of Egr-1 in Late Stage Emphysema
Zhang, Weisu, Yan, Shi Du, Zhu, Aiping, Zou, Yu Shan, Williams, Matthew, Godman, Gabriel C., ...
The transcription factor early growth response (Egr)-1 is an immediate-early gene product rapidly and transiently expressed after acute tissue injury. In contrast, in this report we demonstrate that...
Brett, Jerold, Schmidt, Ann Marie, Yan, Shi Du, Zou, Yu Shan, Weidman, Elliott, Pinsky, David, ...
Advanced glycation end products (AGEs), the final products of nonenzymatic glycation and oxidation of proteins, are found in the plasma and accumulate in the tissues during aging and at an...