Shigenori Nonaka

De Novo Formation of Left–Right Asymmetry by Posterior Tilt of Nodal Cilia (2005)

Shigenori Nonaka, Satoko Yoshiba, Daisuke Watanabe, Shingo Ikeuchi, Tomonobu Goto, Wallace F. Marshall, ...

Left-right asymmetry in the developing mouse embryo is established by leftward fluid flow. Here the authors demonstrate how a posterior tilt of beating cilia creates this unidirectional fluid flow.

De Novo Formation of Left–Right Asymmetry by Posterior Tilt of Nodal Cilia (2005)

Shigenori Nonaka, Satoko Yoshiba, Daisuke Watanabe, Shingo Ikeuchi, Tomonobu Goto, Wallace F. Marshall, ...

In the developing mouse embryo, leftward fluid flow on the ventral side of the node determines left–right (L-R) asymmetry. However, the mechanism by which the rotational movement of node cilia can...

Notch signaling regulates left–right asymmetry determination by inducing Nodal expression

Krebs, Luke T., Iwai, Naomi, Nonaka, Shigenori, Welsh, Ian C., Lan, Yu, Jiang, Rulang, ...

Generation of left–right asymmetry is an integral part of the establishment of the vertebrate body plan. Here we show that the Notch signaling pathway plays a primary role in the establishment of...

De Novo Formation of Left–Right Asymmetry by Posterior Tilt of Nodal Cilia

Nonaka, Shigenori, Yoshiba, Satoko, Watanabe, Daisuke, Ikeuchi, Shingo, Goto, Tomonobu, Marshall, Wallace F, ...

In the developing mouse embryo, leftward fluid flow on the ventral side of the node determines left–right (L-R) asymmetry. However, the mechanism by which the rotational movement of node cilia can...

Notch signaling regulates left–right asymmetry determination by inducing Nodal expression

Krebs, Luke T., Iwai, Naomi, Nonaka, Shigenori, Welsh, Ian C., Lan, Yu, Jiang, Rulang, ...

Generation of left–right asymmetry is an integral part of the establishment of the vertebrate body plan. Here we show that the Notch signaling pathway plays a primary role in the establishment of...

De Novo Formation of Left–Right Asymmetry by Posterior Tilt of Nodal Cilia

Nonaka, Shigenori, Yoshiba, Satoko, Watanabe, Daisuke, Ikeuchi, Shingo, Goto, Tomonobu, Marshall, Wallace F, ...

In the developing mouse embryo, leftward fluid flow on the ventral side of the node determines left–right (L-R) asymmetry. However, the mechanism by which the rotational movement of node cilia can...

Left-Right Asymmetry and Kinesin Superfamily Protein KIF3A: New Insights in Determination of Laterality and Mesoderm Induction by kif3A−/− Mice Analysis

Takeda, Sen, Yonekawa, Yoshiaki, Tanaka, Yosuke, Okada, Yasushi, Nonaka, Shigenori, Hirokawa, Nobutaka

KIF3A is a classical member of the kinesin superfamily proteins (KIFs), ubiquitously expressed although predominantly in neural tissues, and which forms a heterotrimeric KIF3 complex with KIF3B or...